Protein Overview: ATG9

General Information:
Name(s) found:	ATG9 / YDL149W [SGD]
Description(s) found: Found 26 descriptions. SHOW ALL	Transmembrane protein involved in forming Cvt and autophagic vesicles; cycles between the phagophore assembly site (PAS) and other cytosolic punctate structures, not found in autophagosomes; may be involved in membrane delivery to the PAS [SGD]
Organism:	Saccharomyces cerevisiae
Length:	997 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] cytoplasm [IDA] mitochondrion [IDA] integral to membrane [IDA][ISS]
Biological Process:	autophagic vacuole assembly [IMP] autophagy [IMP] protein targeting to vacuole [IMP]
Molecular Function:	identical protein binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERDEYQLPN SHGKNTFLSR IFGLQSDEVN PSLNSQEMSN FPLPDIERGS SLLHSTNDSR  60
   61 EDVDENDLRV PESDQGTSTE EEDEVDEEQV QAYAPQISDG LDGDHQLNSV TSKENVLETE 120
  121 KSNLERLVEG STDDSVPKVG QLSSEEEEDN EFINNDGFDD DTPLFQKSKI HEFSSKKSNT 180
  181 IEDGKRPLFF RHILQNNRPQ RDTQKLFTSS NAIHHDKDKS ANNGPRNING NQKHGTKYFG 240
  241 SATQPRFTGS PLNNTNRFTK LFPLRKPNLL SNISVLNNTP EDRINTLSVK ERALWKWANV 300
  301 ENLDIFLQDV YNYYLGNGFY CIILEKILNI CTLLFVVFVS TYMGHCVDYS KLPTSHRVSD 360
  361 IIIDKCYSNS ITGFTKFFLW MFYFFVILKI VQLYFDVQKL SELQNFYKYL LNISDDELQT 420
  421 LPWQNVIQQL MYLKDQNAMT ANVVEVKAKN RIDAHDVANR IMRRENYLIA LYNSDILNLS 480
  481 LPIPLFRTNV LTKTLEWNIN LCVMGFVFNE SGFIKQSILK PSQREFTREE LQKRFMLAGF 540
  541 LNIILAPFLV TYFVLLYFFR YFNEYKTSPG SIGARQYTPI AEWKFREYNE LYHIFKKRIS 600
  601 LSTTLANKYV DQFPKEKTNL FLKFVSFICG SFVAILAFLT VFDPENFLNF EITSDRSVIF 660
  661 YITILGAIWS VSRNTITQEY HVFDPEETLK ELYEYTHYLP KEWEGRYHKE EIKLEFCKLY 720
  721 NLRIVILLRE LTSLMITPFV LWFSLPSSAG RIVDFFRENS EYVDGLGYVC KYAMFNMKNI 780
  781 DGEDTHSMDE DSLTKKIAVN GSHTLNSKRR SKFTAEDHSD KDLANNKMLQ SYVYFMDDYS 840
  841 NSENLTGKYQ LPAKKGYPNN EGDSFLNNKY SWRKQFQPGQ KPELFRIGKH ALGPGHNISP 900
  901 AIYSTRNPGK NWDNNNNGDD IKNGTNNATA KNDDNNGNND HEYVLTESFL DSGAFPNHDV 960
  961 IDHNKMLNSN YNGNGILNKG GVLGLVKEYY KKSDVGR

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Gavin AC, et al. (2006)		ATG9 RPL18A, RPL18B RPL7A RPS6A, RPS6B
View Details	Gavin AC, et al. (2002)		ASC1 ATG9 CLU1 FUN12 GLT1 HCR1 IST2 KTR5 LSG1 NIP1 NOG1 NOP7 PRT1 RIC1 RLI1 RPG1 SPT5 SUA7 SUI1 SUI2 SUI3 SUP45 TIF34 TIF35 TIF5 UTP6 YGL036W

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
transporter activity	3.99092542545224	bayes_pls_golite062009
transmembrane transporter activity	3.89508301603205	bayes_pls_golite062009
substrate-specific transporter activity	3.77774486920164	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.70710659510165	bayes_pls_golite062009
ion transmembrane transporter activity	3.65362773419219	bayes_pls_golite062009
cation transmembrane transporter activity	3.59612536885223	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	3.31974782515049	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	3.16866260434323	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	3.08808327455436	bayes_pls_golite062009
oxidoreductase activity	2.89313236894612	bayes_pls_golite062009
catalytic activity	1.80540532625606	bayes_pls_golite062009
heme-copper terminal oxidase activity	1.34300351711479	bayes_pls_golite062009
binding	1.20404808556033	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	0.99305432969981	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	0.99305432969981	bayes_pls_golite062009
cytochrome-c oxidase activity	0.99305432969981	bayes_pls_golite062009
protein binding	0.557139661667467	bayes_pls_golite062009
active transmembrane transporter activity	0.347545631980102	bayes_pls_golite062009
primary active transmembrane transporter activity	0.333038681822689	bayes_pls_golite062009

No functions predicted.

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..229]	deduced	N/A	No confident structure predictions are available.
2	View Details	[230..856]	MSA	3.011	View MSA. No confident structure predictions are available.
3	View Details	[857..997]	deduced	N/A	No confident structure predictions are available.

Protein Overview: ATG9

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: