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Protein Overview: ATG9

General Information:
Name(s) found: ATG9 / YDL149W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Transmembrane protein involved in forming Cvt and autophagic vesicles; cycles between the phagophore assembly site (PAS) and other cytosolic punctate structures, not found in autophagosomes; may be involved in membrane delivery to the PAS [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 997 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    integral to membrane [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: autophagic vacuole assembly [IMPLink to PubMed article]
    autophagy [IMPLink to PubMed article]
    protein targeting to vacuole [IMPLink to PubMed article]
    Molecular Function: identical protein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERDEYQLPN SHGKNTFLSR IFGLQSDEVN PSLNSQEMSN FPLPDIERGS SLLHSTNDSR  60
   61 EDVDENDLRV PESDQGTSTE EEDEVDEEQV QAYAPQISDG LDGDHQLNSV TSKENVLETE 120
  121 KSNLERLVEG STDDSVPKVG QLSSEEEEDN EFINNDGFDD DTPLFQKSKI HEFSSKKSNT 180
  181 IEDGKRPLFF RHILQNNRPQ RDTQKLFTSS NAIHHDKDKS ANNGPRNING NQKHGTKYFG 240
  241 SATQPRFTGS PLNNTNRFTK LFPLRKPNLL SNISVLNNTP EDRINTLSVK ERALWKWANV 300
  301 ENLDIFLQDV YNYYLGNGFY CIILEKILNI CTLLFVVFVS TYMGHCVDYS KLPTSHRVSD 360
  361 IIIDKCYSNS ITGFTKFFLW MFYFFVILKI VQLYFDVQKL SELQNFYKYL LNISDDELQT 420
  421 LPWQNVIQQL MYLKDQNAMT ANVVEVKAKN RIDAHDVANR IMRRENYLIA LYNSDILNLS 480
  481 LPIPLFRTNV LTKTLEWNIN LCVMGFVFNE SGFIKQSILK PSQREFTREE LQKRFMLAGF 540
  541 LNIILAPFLV TYFVLLYFFR YFNEYKTSPG SIGARQYTPI AEWKFREYNE LYHIFKKRIS 600
  601 LSTTLANKYV DQFPKEKTNL FLKFVSFICG SFVAILAFLT VFDPENFLNF EITSDRSVIF 660
  661 YITILGAIWS VSRNTITQEY HVFDPEETLK ELYEYTHYLP KEWEGRYHKE EIKLEFCKLY 720
  721 NLRIVILLRE LTSLMITPFV LWFSLPSSAG RIVDFFRENS EYVDGLGYVC KYAMFNMKNI 780
  781 DGEDTHSMDE DSLTKKIAVN GSHTLNSKRR SKFTAEDHSD KDLANNKMLQ SYVYFMDDYS 840
  841 NSENLTGKYQ LPAKKGYPNN EGDSFLNNKY SWRKQFQPGQ KPELFRIGKH ALGPGHNISP 900
  901 AIYSTRNPGK NWDNNNNGDD IKNGTNNATA KNDDNNGNND HEYVLTESFL DSGAFPNHDV 960
  961 IDHNKMLNSN YNGNGILNKG GVLGLVKEYY KKSDVGR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2006) ATG9 RPL18A, RPL18B RPL7A RPS6A, RPS6B
    View Details Gavin AC, et al. (2002) ASC1 ATG9 CLU1 FUN12 GLT1 HCR1 IST2 KTR5 LSG1 NIP1 NOG1 NOP7 PRT1 RIC1 RLI1 RPG1 SPT5 SUA7 SUI1 SUI2 SUI3 SUP45 TIF34 TIF35 TIF5 UTP6 YGL036W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SEC17 ATG9 1 Unpublished Fields Lab Data
    View Screen UBC7 ATG9 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..229] deduced N/A No confident structure predictions are available.
    2 View Details [230..856] MSA 3.011 View MSA. No confident structure predictions are available.
    3 View Details [857..997] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transporter activity
    		•  3.99092542545224 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.89508301603205 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.77774486920164 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.70710659510165 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.65362773419219 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.59612536885223 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  3.31974782515049 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.16866260434323 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  3.08808327455436 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.89313236894612 bayes_pls_golite062009
  • catalytic activity
    		•  1.80540532625606 bayes_pls_golite062009
  • heme-copper terminal oxidase activity
    		•  1.34300351711479 bayes_pls_golite062009
  • binding
    		•  1.20404808556033 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors
    		•  0.99305432969981 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors, oxygen as acceptor
    		•  0.99305432969981 bayes_pls_golite062009
  • cytochrome-c oxidase activity
    		•  0.99305432969981 bayes_pls_golite062009
  • protein binding
    		•  0.557139661667467 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.347545631980102 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.333038681822689 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle