Protein Overview: KRR1

General Information:
Name(s) found:	KRR1 / YCL059C [SGD]
Description(s) found: SHOW ONLY BEST	pir\|\|S19389 hypothetical protein YCL059c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|6319791\|ref\|NP_009872.1\| Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit; Krr1p [Saccharomyces cerevisiae] [NCBI NR] gi\|5300\|emb\|CAA42386.1\| KRR1 [Saccharomyces cerevisiae] [NCBI NR] gi\|51013297\|gb\|AAT92942.1\| YCL059C [Saccharomyces cerevisiae] [NCBI NR] gi\|140400\|sp\|P25586.1\|KRR1_YEAST RecName: Full=Ribosomal RNA assembly protein KRR1; AltName: Full=KRR-R motif-containing protein 1 [NCBI NR] Uncharacterized protein YCL059C - Saccharomyces cerevisiae (Baker's yeast) [Swiss-Prot] Ribosomal RNA assembly protein KRR1 OS=Saccharomyces cerevisiae GN=KRR1 PE=1 SV=1 [Swiss-Prot] KRR1 Protein required for 40S ribosome biogenesis [mips] Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit [SGD] KRR1, Chr III from 22429-23379, reverse complement [yeast_orfs2] Chr III from 22429-23379, reverse complement [yeastorf3.fasta] Chr III from 23379-22429, reverse complement [yeastorf5.fasta] (P25586) Hypothetical 37.2 kDa protein in CHA1-PRD1 intergenic region [4932.FASTACCERV.txt] KRR1 SGDID:S0000564, Chr III from 23379-22429, reverse complement, Verified ORF [yeastflysequest.fasta] Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit [Saccharomyces cerevisiae]gi\|51013297\|gb\|AAT92942.1\| YCL059C [Saccharomyces cerevisiae]gi\|5300\|emb\|CAA42386.1\| KRR1 [Saccharomyces cerevisia [nrdb_11152004_Chlamydomonas] KRR1 SGDID:S000000564, Chr III from 23379-22429, reverse complement, Verified ORF, "Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Uncharacterized protein YCL059C [nr-271106-contam.fasta] KRR1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit; Krr1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YCL059C [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] KRR1 small subunit processome component OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KRR1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] KRR1 SGDID:S000000564, Chr III from 23379-22429, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit" [yeast-030211-contam.fasta] KRR1 SGDID:S000000564, Chr III from 23379-22429, Genome Release 64-2-1, reverse complement, Verified ORF, "Nucleolar protein required for rRNA synthesis and ribosomal assembly; required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit; essential gene" [20141208_orf_trans.fasta] TR1822\|c0_g1_i1\|g.1312 ORF TR1822\|c0_g1_i1\|g.1312 TR1822\|c0_g1_i1\|m.1312 type:complete len:317 (+) TR1822\|c0_g1_i1:67-1017(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] YCL059C SGDID:S000000564, Chr III from 23379-22429, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] ID=asmbl_9177\|g.5648 ORF ID=asmbl_9177\|g.5648 ID=asmbl_9177\|m.5648 type:complete len:317 (+) ID=asmbl_9177:66-1016(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	316 amino acids
Gene Ontology:
Cellular Component:	nuclear outer membrane [IPI] nucleolus [IDA] small nucleolar ribonucleoprotein complex [IPI]
Biological Process:	ribosome biogenesis [IMP][RCA] rRNA processing [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSTHNRDKP WDTDDIDKWK IEEFKEEDNA SGQPFAEESS FMTLFPKYRE SYLKTIWNDV  60
   61 TRALDKHNIA CVLDLVEGSM TVKTTRKTYD PAIILKARDL IKLLARSVPF PQAVKILQDD 120
  121 MACDVIKIGN FVTNKERFVK RRQRLVGPNG NTLKALELLT KCYILVQGNT VSAMGPFKGL 180
  181 KEVRRVVEDC MKNIHPIYHI KELMIKRELA KRPELANEDW SRFLPMFKKR NVARKKPKKI 240
  241 RNVEKKVYTP FPPAQLPRKV DLEIESGEYF LSKREKQMKK LNEQKEKQME REIERQEERA 300
  301 KDFIAPEEEA YKPNQN

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		BMS1 CBF5 ECM16 EMG1 ENP1 ENP2 IMP3 IMP4 KRE33 KRI1 KRR1 MPP10 NOC4 NOP1 NOP14 NOP56 NOP58 NOP6 RCL1 RPS11A, RPS11B RPS4B, RPS4A SOF1 TSR1 UTP20 UTP6 UTP7
View Details	Krogan NJ, et al. (2006)		COQ10 DBP3 DSE4 GAR1 KRI1 KRR1 NHP2 NOP10 NOP6 YCR016W YDR381C-A
View Details	Gavin AC, et al. (2006)		DIP2 EMG1 ENP1 ENP2 ESF1 KRE33 KRR1 MVD1 NOC4 NOP14 NOP6 ROK1 RPL26B UTP22 UTP6 UTP7
View Details	Gavin AC, et al. (2002)		AAR2 ADE4 ADH1 ASC1 BEM2 BFR2 BMS1 BRX1 BUD21 CBF5 CFT2 CIC1 CKA1 CKA2 CKB1 CKB2 CMS1 DBP8 DBP9 DIA4 DIM1 DIP2 DIS3 DRS1 ECM16 ECM29 EMG1 ENP1 ENP2 ERB1 ERO1 ESF1 ESF2 FAP7 FIP1 FUN12 GAR1 GCN1 GLC7 HAS1 HCA4 HHF1, HHF2 HRR25 HSL1 HTA2 IMP3 IMP4 KRE33 KRR1 LCP5 LHP1 LTV1 MAK21 MDN1 MIS1 MPP10 MRD1 MRP7 MVD1 NAN1 NHP2 NIP1 NOB1 NOC2 NOC4 NOG1 NOP1 NOP12 NOP14 NOP2 NOP4 NOP56 NOP58 NOP6 NOP7 NUG1 PAP1 PFS2 PNO1 POL2 PRE6 PRE9 PRP4 PRP43 PTA1 PTI1 PUF6 PWP2 RCL1 REF2 RIO2 RLP7 RML2 RNA14 ROK1 RPP2B RRP12 RRP7 RRP9 RTG2 SAM1 SCL1 SEC21 SLX9 SMB1 SNF2 SNF5 SNU114 SNU66 SOF1 SRO9 SWI3 TIF1, TIF2 TIF4631 TIF4632 TSR1 URB1 UTP10 UTP11 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9 YGR054W YMR310C YOR059C YSH1 YTM1
View Details	Ho Y, et al. (2002)		APL2 APL4 APM1 BRX1 CBF5 CBP2 CIC1 DBP7 DRS1 ENP2 ERB1 HTB1 KAP95 KRE33 KRI1 KRR1 MNP1 MSS116 NMA1 NOG1 NOP2 NOP4 NOP58 NOP6 NOP7 NUG1 PAB1 PUF6 PWP1 RCL1 RPF2 TIF1, TIF2 TIF4631 TIF6 TSR1 TUF1 URB2
View Details	Qiu et al. (2008)		BFR2 BRX1 BUD21 DBP3 DBP7 DBP8 DRS1 EMG1 ENP1 ESF1 FCF2 FPR4 GAR1 HCA4 KRE33 KRR1 LOC1 MAK5 MRT4 NAN1 NOC3 NOP12 NOP13 NOP15 NOP16 NOP2 NOP7 NSR1 NUG1 PUF6 PXR1 RCL1 RPF2 RPL15B RPL19B, RPL19A RPL27A RPL38 RPL4B RPL7A RPL7B RPS10A RPS14B RPS22A RPS22B RRP1 RRP15 RRT14 SLX9 SOF1 SPB4 UTP15 UTP4 UTP8 UTP9 YBL028C

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	KRI1	KRR1	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	KRR1	Huh WK, et al. (2003)
View Data	KRR1 and NOP56	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..123]	ab initio	12.11	No description for 1j4wA was found.
2	View Details	[124..233]	ab initio	12.11	No description for 1j4wA was found.
3	View Details	[234..316]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2