YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: CKB1

General Information:
Name(s) found: CKB1 / YGL019W [SGD]
Description(s) found:
Found 29 descriptions.
SHOW ALL
  • Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB2, the many substrates include transcription factors and all RNA polymerases [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 278 amino acids

    Gene Ontology:
    Cellular Component: protein kinase CK2 complex [IDALink to PubMed article]
    Biological Process: G2/M transition of mitotic cell cycle [IPILink to PubMed article]
    G1/S transition of mitotic cell cycle [IPILink to PubMed article]
    flocculation via cell wall protein-carbohydrate interaction [IMPLink to PubMed article]
    protein amino acid phosphorylation [IDALink to PubMed article]
    response to DNA damage stimulus [IDALink to PubMed article]
    regulation of transcription from RNA polymerase III promoter [IDALink to PubMed article]
    regulation of transcription from RNA polymerase I promoter [IDALink to PubMed article]
    cellular ion homeostasis [IMPLink to PubMed article]
    Molecular Function: protein kinase CK2 regulator activity [IMPLink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQEFVEDYS RTGSSDDEDS GAYDEWIPSF CSRFGHEYFC QVPTEFIEDD FNMTSLSQEV  60
   61 PHYRKALDLI LDLEAMSDEE EDEDDVVEED EVDQEMQSND GHDEGKRRNK SPVVNKSIIE 120
  121 HAAEQLYGLI HARFILTKPG LQAMAEKFDH KEFGTCPRYY CNGMQLLPCG LSDTVGKHTV 180
  181 RLYCPSCQDL YLPQSSRFLC LEGAFWGTSF PGVFLKHFKE LEEYVERKSK ESYELKVFGF 240
  241 RINDEAVSGP RMKWLRQYPS TEEDWEEFAK CEFETPAV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) CDC73 CHD1 CKA1 CKA2 CKB1 CKB2 CTR9 HOT1 LEO1 PAF1 POB3 RRP7 RTF1 SPT16 UTP22
    View Details (MIPS) Mewes HW, et al. (2004) CKA1 CKA2 CKB1 CKB2
    View Details Krogan NJ, et al. (2006) CAB3 CHD1 CKA1 CKA2 CKB1 CKB2 ELF1 HOT1 MSC3 NRG1 PGA2 REH1 RIM13 VHS3 YLR407W
    View Details Gavin AC, et al. (2006) CKA1 CKA2 CKB1 CKB2
    View Details Gavin AC, et al. (2002) ABF2 ADE4 APL1 APL3 APL5 APL6 APM3 APM4 APS2 APS3 ASC1 BDF2 BFR2 BMH1 BMS1 BRX1 BUD21 CAB3 CBF5 CDC55 CDC73 CHD1 CKA1 CKA2 CKB1 CKB2 CMS1 CTI6 CTR9 DBP2 DBP8 DEP1 DIA4 DIM1 DIP2 DIS3 DOT6 DYN1 EAF3 ECM16 ECM29 ECM5 EMG1 ENO2 ENP1 ENP2 ERO1 ESF1 ESF2 FAP7 GAL83 GCN1 GLY1 HAT1 HAT2 HCA4 HHF1, HHF2 HIF1 HOT1 HSL1 HSM3 HTA2 ICL1 IML1 IMP3 IMP4 IOC3 ISW1 ISW2 KAP123 KRE33 KRR1 LCP5 LEO1 LIP2 LTV1 LYS12 MAC1 MDN1 MED4 MIS1 MPP10 MRD1 MRPS28 MSB1 MVD1 NAN1 NHP10 NIP1 NMD5 NOB1 NOC2 NOC4 NOP1 NOP14 NOP56 NOP58 NOP6 NRD1 NUP120 NUP145 NUP84 NUP85 PAF1 PFK1 PHO23 PNO1 POB3 PRE6 PRE9 PRO1 PRP43 PRT1 PSD2 PSE1 PSH1 PWP2 RCL1 RCO1 REG1 RET1 RML2 ROK1 RPA135 RPC40 RPD3 RPG1 RPN12 RPN3 RPN6 RPN8 RPN9 RPP2B RPT2 RPT3 RPT5 RPT6 RRP12 RRP7 RRP9 RSC3 RSC8 RTF1 RTG2 RVB2 RXT2 RXT3 SAK1 SAM1 SAP30 SCL1 SDS3 SEC13 SEC16 SEC21 SEC23 SEC31 SEH1 SIN3 SIP1 SIP2 SLX9 SNF1 SNF4 SOF1 SPN1 SPT16 SPT6 SSA4 STM1 STO1 TEL1 TIF1, TIF2 TIF35 TOP1 TSC11 TSR1 TUP1 UME1 UME6 USO1 UTP10 UTP11 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9 VPS1 VTH2 YFR006W YOR059C YPR077C YTA7
    View Details Ho Y, et al. (2002) BRX1 CDC28 CDC33 CEG1 CIC1 CKA1 CKA2 CKB1 CKB2 COX6 DBP10 DBP2 DIP2 DUN1 EGD1 ENP2 ERB1 ESF1 ESF2 ESL2 FET4 FKH1 FPR3 FYV8 GAR1 GCD2 GCD7 GCN3 GDE1 HAS1 HHF1, HHF2 HHT1, HHT2 HOT1 HTA1 HTB1 HTB2 IMD2 IMD3 KRE33 KRI1 LAA1 LCP5 LHP1 MBP1 MGM101 MPH1 MRPL1 MSS116 NAN1 NET1 NIP7 NMD3 NOC2 NOC3 NOG1 NOP1 NOP12 NOP2 NOP4 NOP56 NOP7 NSA1 NSA2 NUG1 PDI1 PHO84 PMA1 PNO1 POB3 POL2 PRP40 PTC5 PUF6 PWP1 PWP2 RNH203 RPF2 RRP1 RRP14 RRP5 SAH1 SEC2 SFP1 SIN3 SPT16 SPT2 SSF1 SUI2 SUI3 TFP1 TIF4631 TIF6 TOP2 TRL1 UBP12 URE2 UTP10 UTP11 UTP13 UTP14 UTP18 UTP21 UTP22 UTP30 UTP6 VMR1 VPS73 WTM2 YCR087W YDR102C YER084W YGR017W YMR144W YPL009C YRA1
    View Details Qiu et al. (2008) CKA1 CKA2 CKB1 CKB2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run ASF1 3906: TAP-tagged Green EM, et al (2005)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CKB1 TCB2 2 Unpublished Fields Lab Data
    View Screen CKB1 YNL234W 2 Unpublished Fields Lab Data
    View Screen CKB1 CKB2 2 Unpublished Fields Lab Data
    View Screen CKB1 CKA2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data CKB1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..29]
    [43..127]    		 PSI-BLAST 530.70927 Casein kinase II beta subunit
    2 View Details [30..42]
    [128..278]    		 PSI-BLAST 530.70927 Casein kinase II beta subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein kinase regulator activity
    		•  4.14878012076359 bayes_pls_golite062009
  • kinase regulator activity
    		•  4.09603095102334 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.91779610785511 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.79245883940915 bayes_pls_golite062009
  • protein kinase activity
    		•  2.75473427458132 bayes_pls_golite062009
  • kinase activity
    		•  2.66515798949431 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.39333807060713 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  1.99491617326192 bayes_pls_golite062009
  • binding
    		•  1.85951177140712 bayes_pls_golite062009
  • transferase activity
    		•  1.77218599619559 bayes_pls_golite062009
  • protein binding
    		•  1.4657010373022 bayes_pls_golite062009
  • catalytic activity
    		•  0.2012862421225 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle