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Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). Interacting selectively and non-covalently with dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms. Interacting selectively and non-covalently with an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. Interacting selectively and non-covalently with any component on the surface of a cell. Interacting selectively and non-covalently with ions, charged atoms or groups of atoms. Interacting selectively and non-covalently with a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters. Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose moiety. Interacting selectively and non-covalently with hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentine. The binding activity of a molecule that brings together two or more molecules, permitting those molecules to function in a coordinated way. Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. Interacting selectively and non-covalently with nitric oxide (NO). Interacting selectively and non-covalently with carbon monoxide (CO). Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. Interacting selectively and non-covalently with an organic acid, any acidic compound containing carbon in covalent linkage. Interacting selectively and non-covalently with an alcohol, any of a class of alkyl compounds containing a hydroxyl group. Interacting selectively and non-covalently with a component of the extracellular matrix. Interacting selectively and non-covalently with a virion, either by binding to components of the capsid or the viral envelope. Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell. Interacting selectively and non-covalently with suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms. Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). Interacting selectively and non-covalently with boron, the group 13 element with properties which are borderline between metals and non-metals. Interacting selectively and non-covalently with a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups. Interacting selectively and non-covalently with an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid. Interacting selectively and non-covalently with lipoteichoic acid. Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone. Interacting selectively and non-covalently with a pigment, any general or particular coloring matter in living organisms, e.g. melanin. Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. Interacting selectively and non-covalently with poly(3-hydroxyalkanoate)s, polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria. Interacting selectively and non-covalently with a lipid. Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. Interacting selectively and non-covalently with selenium (Se). Interacting selectively and non-covalently with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose. Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease. null Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds. Interacting selectively and non-covalently with a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases. Interacting selectively and non-covalently with any nucleic acid. Interacting selectively and non-covalently with a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position. Interacting selectively and non-covalently with a microfibril, any small fibril occurring in biological material. Interacting selectively and non-covalently with calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi. Interacting selectively and non-covalently with water (H2O). Interacting selectively and non-covalently with lipopolysaccharide. Interacting selectively and non-covalently with oxygen (O2). The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. Interacting selectively and non-covalently with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. Interacting selectively and non-covalently with a toxin, a poisonous substance that causes damage to biological systems. Toxins are differentiated from simple chemical poisons and vegetable alkaloids by their high molecular weight and antigenicity (they elicit an antibody response). Interacting selectively and non-covalently with a repeating or polymeric structure, such as a polysaccharide or peptidoglycan. Interacting selectively and non-covalently with any complex of RNA and protein. Interacting selectively and non-covalently with any carbohydrate, any of a group of organic compounds based of the general formula Cx(H2O)y. Interacting selectively and non-covalently with a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached. Interacting selectively and non-covalently with the surface of a host cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: binding
Acc: GO:0005488
Aspect: Molecular Function
Desc: The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
Synonyms:
  • ligand
Proteins in PDR annotated with:
   This term: 3617 [Search]
   Term or descendants: 62862 [Refine Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005488 - binding (interactive image map)
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Created and Maintained by: Michael Riffle