YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: DBP10

General Information:
Name(s) found: DBP10 / YDL031W [SGD]
Description(s) found:
Found 20 descriptions.
SHOW ALL
  • Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal particles; essential protein involved in ribosome biogenesis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 995 amino acids

    Gene Ontology:
    Cellular Component: nuclear outer membrane [TASLink to PubMed article]
    nucleolus [IDALink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    ribosomal large subunit assembly [IMPLink to PubMed article]
    Molecular Function: ATP-dependent RNA helicase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGVQKRKRD LEDQDDNGSE EDDIAFDIAN EIALNDSESD ANDSDSEVEA DYGPNDVQDV  60
   61 IEYSSDEEEG VNNKKKAENK DIKKKKNSKK EIAAFPMLEM SDDENNASGK TQTGDDEDDV 120
  121 NEYFSTNNLE KTKHKKGSFP SFGLSKIVLN NIKRKGFRQP TPIQRKTIPL ILQSRDIVGM 180
  181 ARTGSGKTAA FILPMVEKLK SHSGKIGARA VILSPSRELA MQTFNVFKDF ARGTELRSVL 240
  241 LTGGDSLEEQ FGMMMTNPDV IIATPGRFLH LKVEMNLDLK SVEYVVFDEA DRLFEMGFQE 300
  301 QLNELLASLP TTRQTLLFSA TLPNSLVDFV KAGLVNPVLV RLDAETKVSE NLEMLFLSSK 360
  361 NADREANLLY ILQEIIKIPL ATSEQLQKLQ NSNNEADSDS DDENDRQKKR RNFKKEKFRK 420
  421 QKMPAANELP SEKATILFVP TRHHVEYISQ LLRDCGYLIS YIYGTLDQHA RKRQLYNFRA 480
  481 GLTSILVVTD VAARGVDIPM LANVINYTLP GSSKIFVHRV GRTARAGNKG WAYSIVAENE 540
  541 LPYLLDLELF LGKKILLTPM YDSLVDVMKK RWIDEGKPEY QFQPPKLSYT KRLVLGSCPR 600
  601 LDVEGLGDLY KNLMSSNFDL QLAKKTAMKA EKLYYRTRTS ASPESLKRSK EIISSGWDAQ 660
  661 NAFFGKNEEK EKLDFLAKLQ NRRNKETVFE FTRNPDDEMA VFMKRRRKQL APIQRKATER 720
  721 RELLEKERMA GLHILSKMKF WKGDDVETGY TVSEDALKEF EDAHQLLEAQ ENENKKKKKP 780
  781 KSFKDPTFFL SHYAPAGDIQ DKQLQITNGF ANDAAQAAYD LNSDDKVQVH KQTATVKWDK 840
  841 KRKKYVNTQG IDNKKYIIGE SGQKIAASFR SGRFDDWSKA RNLKPLKVGS RETSIPSNLL 900
  901 EDPSQGPAAN GRTVRGKFKH KQMKAPKMPD KHRDNYYSQK KKVEKALQSG ISVKGYNNAP 960
  961 GLRSELKSTE QIRKDRIIAE KKRAKNARPS KKRKF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARX1 BRX1 CIC1 DBP10 DBP9 DRS1 EBP2 ERB1 FPR4 HAS1 IPI3 LOC1 MAK21 MRT4 NIP7 NOC2 NOC3 NOG1 NOG2 NOP15 NOP2 NOP4 NOP7 NSA1 NSA2 NUG1 PUF6 RIX1 RIX7 RLP7 RPF1 RPF2 RPL25 RRP1 SDA1 SPB1 SPB4 SSF1 TIF6 URB1 YTM1
    View Details Krogan NJ, et al. (2006) DBP10 RTT107
    View Details Gavin AC, et al. (2006) DBP10 DBP9 NOP13 NOP4 PUF6
    View Details Gavin AC, et al. (2002) ARX1 BEM2 BMS1 BRX1 BUD20 CIC1 CLU1 CYR1 CYS4 DBP10 DBP9 DCP2 DRS1 EBP2 ERB1 FPR4 GCN1 HAS1 HDA1 HER1 HIS3 INP2 IPI1 IPI3 KRE33 LHP1 LOC1 LSG1 MAK21 MAK5 MDN1 MIS1 MRT4 NAP1 NIP1 NIP7 NMD3 NOC2 NOC3 NOG1 NOG2 NOP1 NOP12 NOP15 NOP16 NOP2 NOP4 NOP56 NOP7 NSA1 NSA2 NUG1 PRT1 PUF6 REI1 RIX1 RIX7 RLP24 RLP7 RPA135 RPA190 RPF1 RPF2 RPG1 RPP2B RPT6 RRP1 RRP12 RSA3 RSA4 RTR1 SDA1 SEC7 SKI2 SNU13 SPB1 SPB4 SSF1 TIF6 TUB3 URB1 UTP10 UTP20 UTP22 YGL036W YTM1
    View Details Ho Y, et al. (2002) BMS1 CDC53 CIC1 CKA1 CKA2 CKB1 CKB2 COF1 CTF4 DBP10 DED81 DIA2 ENP1 ENP2 FPR3 GDE1 HAS1 HHF1, HHF2 HOT1 ILS1 KRE33 KRI1 LST4 MAM33 MCM2 MCM3 MCM5 MRPL1 NIP7 NMD3 NOC3 NOP1 NOP12 NOP2 NOP7 NUG1 PDI1 POB3 POL2 PUF6 PWP1 RPF2 RRP1 RRP12 RRP14 RRP15 RRP5 SEH1 SFP1 SKP1 SLT2 SPB1 SPT16 SRP1 SSF1 SSF2 SSZ1 TIF4631 TIF6 TRL1 URB1 UTP10 UTP22 VMR1 VPS73 WTM2 YAK1 YBL104C YRA1 YTM1
    View Details Qiu et al. (2008) DBP10 DBP3 DBP6 DBP7 DBP8 DHR2 DRS1 HAS1 HCA4 MAK5 MTR4 ROK1 RRP3 SPB4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run DAD1 No Comments Cheeseman IM, et al. (2002)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..99] deduced N/A No confident structure predictions are available.
    2 View Details [100..347] PSI-BLAST 419.9794 Putative DEAD box RNA helicase
    3 View Details [348..480] PSI-BLAST 419.9794 Putative DEAD box RNA helicase
    4 View Details [481..577] ab initio 13.84 No description for 1gkuB was found.
    5 View Details [578..665] deduced N/A Confident ab initio structure predictions are available.
    6 View Details [666..899] MSA 1.014962 View MSA. No confident structure predictions are available.
    7 View Details [900..995] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle