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Protein Overview: RSA3

General Information:
Name(s) found: RSA3 / YLR221C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Protein with a likely role in ribosomal maturation, required for accumulation of wild-type levels of large (60S) ribosomal subunits; binds to the helicase Dbp6p in pre-60S ribosomal particles in the nucleolus [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 220 amino acids

    Gene Ontology:
    Cellular Component: nucleolus [IDALink to PubMed article]
    preribosome, large subunit precursor [IDALink to PubMed article]
    Biological Process: ribosomal large subunit assembly [IGILink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAGDISAIN IKSVKKNRRR KKRRTADVSS SDSSSSDPSS ESEKEEIQNG AIEEHVGENG  60
   61 KSDHVFSKGN DEDKQEDIAI EVSDVELTDE ESKDLKLNSK EVIDDLTKIS LSKIPEPTKS 120
  121 QNKEGFMNAS KIAENIKLAR EEYNELAENF VPKGKDKTKL REEYLNLLFE NYGDDINRLR 180
  181 AAPDFTNKSL SILADALQEG IGMFDIGELE LVLKNKEMEN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BUD22 CIC1 DBP6 EFG1 FRE3 GIS2 HAS1 MAK21 NIP7 NOB1 NOC2 NOC3 NOP1 NOP2 NOP8 PUS7 RRP5 RSA3 SBP1 SFA1 SSQ1 YGR272C YMR034C YRF1-8, YRF1-5, ...
    View Details Gavin AC, et al. (2006) DBP9 MAK21 MAK5 NOP4 RLP7 RPL26B RPL33B RPP2B RPS16B, RPS16A RSA3 YOR1 YTM1
    View Details Gavin AC, et al. (2002) ACT1 AIM31 ARX1 BEM2 BMS1 BRX1 BUD20 CFT1 CFT2 CIC1 CKA1 CLP1 CLU1 CYR1 CYS4 DBP10 DBP9 DCP2 DRS1 EBP2 ENO2 ERB1 FIP1 FPR4 GCN1 GLC7 HAS1 HDA1 HER1 HHF1, HHF2 HIS3 HTA1 INP2 IPI1 IPI3 KRE33 LHP1 LOC1 LSG1 MAK21 MAK5 MDN1 MIS1 MPE1 MRT4 NAP1 NIP1 NIP7 NMD3 NOC2 NOC3 NOG1 NOG2 NOP1 NOP12 NOP15 NOP16 NOP2 NOP4 NOP56 NOP7 NSA1 NSA2 NUG1 PAP1 PCF11 PFK1 PFS2 PRT1 PTA1 PTI1 PUF6 REF2 REI1 RIX1 RIX7 RLP24 RLP7 RNA14 RNA15 RPA135 RPA190 RPF1 RPF2 RPG1 RPP2B RPT6 RRP1 RRP12 RSA3 RSA4 RTR1 SDA1 SEC13 SEC31 SEC7 SKI2 SNU13 SPB1 SPB4 SSA3 SSF1 SSU72 SYC1 TAF6 TIF4632 TIF6 TUB3 TYE7 URB1 UTP10 UTP20 UTP22 VID24 VMR1 VPS53 YCL046W YGL036W YSH1 YTH1 YTM1
    View Details Qiu et al. (2008) DBP6 LTV1 MAK21 NOC2 PWP2 RSA3

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RSA3 and NOP56 Huh WK, et al. (2003)
    View Data RSA3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..220] MSA 1.002997 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle