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View Structure Prediction Details

Protein: CKB1
Organism: Saccharomyces cerevisiae
Length: 278 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CKB1.

Description E-value Query
Range		 Subject
Range
gi|190406988 - gi|190406988|gb|EDV10255.1| protein kinase CK2 beta subunit [Saccharomyces cerevisiae RM11-1a]
CKB1 - Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and p...
CSK2B_YEAST - Casein kinase II subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CKB1 PE=1 ...
ORFP:8446 - YGL019W, Contig c17 3110-3946 reverse complement
gi|151943269 - gi|151943269|gb|EDN61582.1| protein kinase CK2 beta subunit [Saccharomyces cerevisiae YJM789]
 0.0 [1..278] [1..278]
tr|G3HZG2|G3HZG2... - Casein kinase II subunit beta OS=Cricetulus griseus GN=H671_1g2786 PE=3 SV=1
gi|53734598 - gb|AAH83993.1| Unknown (protein for MGC:98116) [Xenopus laevis]
CSK2B_RAT - Casein kinase II subunit beta OS=Rattus norvegicus GN=Csnk2b PE=1 SV=1
CSNK2B - casein kinase 2, beta polypeptide
CSK2B_PIG - Casein kinase II subunit beta OS=Sus scrofa GN=CSNK2B PE=2 SV=1
CSK2B_RABIT - Casein kinase II subunit beta OS=Oryctolagus cuniculus GN=CSNK2B PE=2 SV=1
gi|213688918, gi... - gi|215983072|ref|NP_001135983.1| casein kinase 2, beta polypeptide [Ovis aries], gi|213688918|gb|ACJ...
CSK2B_MOUSE - Casein kinase II subunit beta OS=Mus musculus GN=Csnk2b PE=1 SV=1
gi|109070472 - gi|109070472|ref|XP_001112478.1| PREDICTED: similar to casein kinase 2, beta subunit isoform 1 [Maca...
CSK2B_CHICK - Casein kinase II subunit beta OS=Gallus gallus GN=CSNK2B PE=2 SV=1
ENSPTRT00000057498 - null
tr|M3W831|M3W831... - Casein kinase II subunit beta OS=Felis catus GN=CSNK2B PE=3 SV=1
CSK2B_BOVIN - Casein kinase II subunit beta OS=Bos taurus GN=CSNK2B PE=1 SV=1
gi|194223340 - gi|194223340|ref|XP_001917725.1| PREDICTED: similar to casein kinase 2, beta polypeptide isoform 1 [...
 5.0E-97 [19..247] [2..197]
CSK2B_DANRE - Casein kinase II subunit beta OS=Danio rerio GN=csnk2b PE=2 SV=1
gi|11280586, gi|... - gi|7672353|gb|AAF66446.1|AF133088_1 CK2 beta subunit [Cyprinus carpio], gi|11280586|pir||JC7269 prot...
gi|223649430, gi... - gi|223649430|gb|ACN11473.1| Casein kinase II subunit beta [Salmo salar], gi|223648390|gb|ACN10953.1|...
 5.0E-97 [19..247] [2..197]
CSK2B_XENLA - Casein kinase II subunit beta OS=Xenopus laevis GN=csnk2b PE=1 SV=1
gi|49899997, gi|... - gi|89271289|emb|CAJ82633.1| casein kinase 2, beta subunit [Xenopus tropicalis], gi|52346076|ref|NP_0...
 7.0E-97 [19..247] [2..197]
gi|181155 - gi|181155|gb|AAA52123.1| casein kinase II beta subunit [Homo sapiens]
 9.0E-97 [19..247] [2..197]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 9.0E-96 [22..247] [1..193]
gi|218185028 - gi|218185028|gb|EEC67455.1| hypothetical protein OsI_34680 [Oryza sativa Indica Group]
gi|12597893, gi|... - gi|37536920|ref|NP_922762.1| putative casein kinase II beta subunit [Oryza sativa (japonica cultivar...
 7.0E-95 [8..246] [75..280]
CSK2E_ARATH - Putative casein kinase II subunit beta-4 OS=Arabidopsis thaliana GN=At2g44680 PE=2 SV=1
 1.0E-94 [2..245] [72..282]

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Predicted Domain #1
Region A:
Residues: [1-29] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQEFVEDYS RTGSSDDEDS GAYDEWIPS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [43-127] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTEFIEDDFN MTSLSQEVPH YRKALDLILD LEAMSDEEED EDDVVEEDEV DQEMQSNDGH  60
   61 DEGKRRNKSP VVNKSIIEHA AEQLY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 530.70927
Match: 1jwhC_
Description: Casein kinase II beta subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein kinase regulator activity 4.14878012076359 bayes_pls_golite062009
kinase regulator activity 4.09603095102334 bayes_pls_golite062009
enzyme regulator activity 2.91779610785511 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.79245883940915 bayes_pls_golite062009
protein kinase activity 2.75473427458132 bayes_pls_golite062009
kinase activity 2.66515798949431 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.39333807060713 bayes_pls_golite062009
protein serine/threonine kinase activity 1.99491617326192 bayes_pls_golite062009
binding 1.85951177140712 bayes_pls_golite062009
transferase activity 1.77218599619559 bayes_pls_golite062009
protein binding 1.4657010373022 bayes_pls_golite062009
catalytic activity 0.2012862421225 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [30-42] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FCSRFGHEYF CQV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [128-278] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLIHARFILT KPGLQAMAEK FDHKEFGTCP RYYCNGMQLL PCGLSDTVGK HTVRLYCPSC  60
   61 QDLYLPQSSR FLCLEGAFWG TSFPGVFLKH FKELEEYVER KSKESYELKV FGFRINDEAV 120
  121 SGPRMKWLRQ YPSTEEDWEE FAKCEFETPA V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 530.70927
Match: 1jwhC_
Description: Casein kinase II beta subunit
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle