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Protein Overview: SUI3

General Information:
Name(s) found: SUI3 / YPL237W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 285 amino acids

    Gene Ontology:
    Cellular Component: multi-eIF complex [IDALink to PubMed article]
    ribosome [TASLink to PubMed article]
    eukaryotic translation initiation factor 2 complex [IMPLink to PubMed article][ISSLink to PubMed article]
    Biological Process: translational initiation [TASLink to PubMed article]
    Molecular Function: translation initiation factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDLAAELG FDPALKKKKK TKKVIPDDFD AAVNGKENGS GDDLFAGLKK KKKKSKSVSA  60
   61 DAEAEKEPTD DIAEALGELS LKKKKKKTKD SSVDAFEKEL AKAGLDNVDA ESKEGTPSAN 120
  121 SSIQQEVGLP YSELLSRFFN ILRTNNPELA GDRSGPKFRI PPPVCLRDGK KTIFSNIQDI 180
  181 AEKLHRSPEH LIQYLFAELG TSGSVDGQKR LVIKGKFQSK QMENVLRRYI LEYVTCKTCK 240
  241 SINTELKREQ SNRLFFMVCK SCGSTRSVSS IKTGFQATVG KRRRM

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) GCD1 GCD11 GCD2 GCD6 GCD7 GCN3 NIP1 PRT1 SUI2 SUI3
    View Details (MIPS) Mewes HW, et al. (2004) GCD11 SUI2 SUI3
    View Details Gavin AC, et al. (2002) ASC1 ATG9 CBF5 CCT4 CDC33 CHC1 CLU1 COG8 CRN1 DBP2 ECM29 FUN12 GCD1 GCD11 GCD2 GCD6 GCD7 GCN3 GLT1 GUT1 HCR1 HEK2 HHF1, HHF2 IST1 IST2 KAP123 KTR5 LHP1 LSG1 MEC1 MIP6 MIS1 MRP7 MRPL23 NAB3 NAB6 NIP1 NOG1 NOP7 NRD1 PDC1 POL2 PRO1 PRT1 PUS7 RBG1 RIC1 RLI1 ROM2 RPA135 RPG1 RRP40 RRP46 SBP1 SEN54 SNP1 SPT5 SRO9 STM1 STO1 SUA7 SUI1 SUI2 SUI3 SUP35 SUP45 TAO3 TIF1, TIF2 TIF34 TIF35 TIF4631 TIF4632 TIF5 USO1 UTP20 UTP6 VAC14 VPS5 XKS1 YGL036W YJL017W YMR310C
    View Details Ho Y, et al. (2002) CDC28 CDC33 CEG1 CFT1 CIC1 CKA1 CKA2 CKB1 CKB2 CLU1 ERB1 FAA4 FAL1 FET3 FIN1 FIP1 FKH1 FPR3 FPR4 FYV8 GCD1 GCD11 GCD2 GCD6 GCD7 GCN3 GLC7 GLC8 GPH1 HER1 HHF1, HHF2 HTB1 KEL1 LOS1 MBP1 MET18 MGM101 MHP1 MPH1 NET1 NMD5 NOP1 NSA1 PRO3 REG1 RRP1 RRP17 SCD5 SCW4 SDS22 SEC2 SEN1 SIN3 SPB1 SUI2 SUI3 THR4 TIF1, TIF2 TIF4631 TIF4632 UBP12 URE2 VAC8 VMA8 YGR017W YMR144W YTM1
    View Details Qiu et al. (2008) ANB1 FUN12 GCD11 NIP1 PRT1 RPG1 SUI1 SUI2 SUI3 TIF11 TIF3 TIF34 TIF35 TIF5 YGR054W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run BOI1 Sample bob1 (2nd set) from october 2005 McCusker D, et al (2007)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..124] MSA 1.037996 View MSA. No confident structure predictions are available.
    2 View Details [125..217] PSI-BLAST 11.0 Zinc-binding domain of translation initiation factor 2 beta
    3 View Details [218..285] PSI-BLAST 7.69897 Zinc-binding domain of translation initiation factor 2 beta


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle