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Protein Overview: MEC1

Protein Complex Data

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run PAN1 No Comments Toshima J, et al (2006)
View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
View Run RPA135 No Comments Schneider, DA, et al. (2006)
View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..555] deduced N/A No confident structure predictions are available.
2 View Details [556..974] MSA 1.018981 View MSA. No confident structure predictions are available.
3 View Details [975..1241] deduced N/A No confident structure predictions are available.
4 View Details [1242..1376] MSA 1.040997 View MSA. Confident ab initio structure predictions are available.
5 View Details [1377..1817] Pfam 68.026872 FAT domain No confident structure predictions are available.
6 View Details [1818..1972] PSI-BLAST 166.9897 Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain
7 View Details [1973..2133]
[2294..2322]
PSI-BLAST 166.9897 Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain
8 View Details [2134..2293]
[2323..2368]
PSI-BLAST 166.9897 Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain
9 View Details [1644..1820] PSI-BLAST 5.69897 Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form)
10 View Details [1821..2368] PSI-BLAST 105.0 Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain

Functions predicted (by domain):

# Gene Ontology predictions
1 No functions predicted.
2 No functions predicted.
3 No functions predicted.
4
Term Confidence Notes
  • binding
  • 2.96084803796407 bayes_pls_golite062009
  • protein binding
  • 2.66176697577398 bayes_pls_golite062009
  • nucleic acid binding
  • 2.39117996950187 bayes_pls_golite062009
  • transcription regulator activity
  • 1.93307188158984 bayes_pls_golite062009
  • DNA binding
  • 1.77969838181048 bayes_pls_golite062009
  • protein transporter activity
  • 1.51072955431931 bayes_pls_golite062009
  • protein kinase activity
  • 1.40981221970766 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
  • 1.19667256014399 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
  • 1.18159704569055 bayes_pls_golite062009
  • kinase activity
  • 1.155617721412 bayes_pls_golite062009
  • transcription factor activity
  • 1.02508422532466 bayes_pls_golite062009
  • substrate-specific transporter activity
  • 0.68280791022469 bayes_pls_golite062009
  • protein serine/threonine kinase activity
  • 0.647706371567682 bayes_pls_golite062009
  • transferase activity
  • 0.567560860286018 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
  • 0.19278880370842 bayes_pls_golite062009
  • hydrolase activity
  • 0.0962597719675237 bayes_pls_golite062009
  • clathrin binding
  • 0.0923079381755934 bayes_pls_golite062009
  • transcription activator activity
  • 0.061709024440191 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.
    10 No functions predicted.




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle