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Protein Overview: MRT4

General Information:
Name(s) found: MRT4 / YKL009W [SGD]
Description(s) found:
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  • gi|6322843|ref|NP_012916.1| Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus; Mrt4p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|485985|emb|CAA81844.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|465665|sp|P33201.1|MRT4_YEAST RecName: Full=mRNA turnover protein 4 [NCBI NR]
  • pir||S30013 hypothetical protein YKL009w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|263500|gb|AAB24904.1| ribosomal protein L10 homolog [Saccharomyces cerevisiae] [NCBI NR]
  • mRNA turnover protein 4 OS=Saccharomyces cerevisiae GN=MRT4 PE=1 SV=1 [Swiss-Prot]
  • MRT4 mRNA turnover 4 [mips]
  • Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus [SGD]
  • MRT4, Chr XI from 425880-426590 [yeast_orfs2]
  • Chr XI from 425880-426590 [yeastorf3.fasta]
  • (P33201) Hypothetical 27.1 kDa protein UFD4-CAP1 intergenic region [4932.FASTACCERV.txt]
  • MRT4 SGDID:S0001492, Chr XI from 425885-426595, Verified ORF [yeastflysequest.fasta]
  • Mrt4p [Saccharomyces cerevisiae]gi|485985|emb|CAA81844.1| unnamed protein product [Saccharomyces cerevisiae]gi|320758|pir||S30013 hypothetical protein YKL009w - yeast (Saccharomyces cerevisiae)gi|263500|gb|AAB24904.1| ribosomal protein L10 homolog [Sac [nrdb_11152004_Chlamydomonas]
  • (P33201) mRNA turnover protein 4 [cerv4932.FASTAC]
  • MRT4 SGDID:S000001492, Chr XI from 425885-426595, Verified ORF, "Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • ribosomal protein L10 homolog [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • mRNA turnover protein 4 [nr-271106-contam.fasta]
  • Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus; Mrt4p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • mRNA turnover protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MRT4 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • MRT4 SGDID:S000001492, Chr XI from 426242-426952, Genome Release 64-1-1, Verified ORF, "Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus" [yeast-030211-contam.fasta]
  • MRT4 SGDID:S000001492, Chr XI from 426242-426952, Genome Release 64-2-1, Verified ORF, "Protein involved in mRNA turnover and ribosome assembly; required at post-transcriptional step for efficient retrotransposition; localizes to the nucleolus" [20141208_orf_trans.fasta]
  • TR1108|c0_g1_i1|g.868 ORF TR1108|c0_g1_i1|g.868 TR1108|c0_g1_i1|m.868 type:complete len:237 (+) TR1108|c0_g1_i1:115-825(+) [Y12_S_cerevisiae-Sep2015-contam.fasta]
  • YKL009W SGDID:S000001492, Chr XI from 426242-426952, Genome Release 64-1-1, Verified ORF, "Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
  • asmbl_6682|g.4953 ORF asmbl_6682|g.4953 asmbl_6682|m.4953 type:complete len:237 (+) asmbl_6682:70-780(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta]
  • Ribosome assembly factor MRT4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MRT4 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
  • ID=asmbl_6701|g.4022 ORF ID=asmbl_6701|g.4022 ID=asmbl_6701|m.4022 type:complete len:237 (+) ID=asmbl_6701:70-780(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 236 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nucleolus [IDALink to PubMed article]
    Biological Process: ribosomal large subunit biogenesis [IMPLink to PubMed article][IPILink to PubMed article]
    telomere maintenance [IMPLink to PubMed article]
    ribosome biogenesis [RCALink to PubMed article]
    rRNA processing [IMPLink to PubMed article]
    mRNA catabolic process [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRSKRSKLV TLAQTDKKGR ENKERIFDEV REALDTYRYV WVLHLDDVRT PVLQEIRTSW  60
   61 AGSKLIMGKR KVLQKALGEK REEEYKENLY QLSKLCSGVT GLLFTDEDVN TVKEYFKSYV 120
  121 RSDYSRPNTK APLTFTIPEG IVYSRGGQIP AEEDVPMIHS LEPTMRNKFE IPTKIKAGKI 180
  181 TIDSPYLVCT EGEKLDVRQA LILKQFGIAA SEFKVKVSAY YDNDSSTVES TNINME

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARX1 BRX1 CIC1 DBP10 DRS1 ERB1 HAS1 IPI1 IPI3 LOC1 MRT4 NAB2 NIP7 NOC2 NOC3 NOG1 NOG2 NOP15 NOP2 NOP7 NSA1 NSA2 NUG1 PUF6 RIX1 RLP7 RPF1 RPF2 RPL31B RPL36B RSA4 SDA1 SPB4 TIF6 YTM1
    View Details Krogan NJ, et al. (2006) AHP1 MRT4 SSB2
    View Details Gavin AC, et al. (2006) ARX1 FPR4 MRT4 NIP7 NOG1 NOG2 NOP2 NSA2 NUG1 RPF2 SDA1 TIF6
    View Details Gavin AC, et al. (2002) ARX1 BEM2 BMS1 BRX1 BUD20 CIC1 CLU1 CYR1 CYS4 DBP10 DBP9 DCP2 DRS1 EBP2 ERB1 FPR4 GCN1 HAS1 HDA1 HER1 HIS3 INP2 IPI1 IPI3 KRE33 LHP1 LOC1 LSG1 MAK21 MAK5 MDN1 MIS1 MRT4 NAP1 NIP1 NIP7 NMD3 NOC2 NOC3 NOG1 NOG2 NOP1 NOP12 NOP15 NOP16 NOP2 NOP4 NOP56 NOP7 NSA1 NSA2 NUG1 PRT1 PUF6 REI1 RIX1 RIX7 RLP24 RLP7 RPA135 RPA190 RPF1 RPF2 RPG1 RPP2B RPT6 RRP1 RRP12 RSA3 RSA4 RTR1 SDA1 SEC7 SKI2 SNU13 SPB1 SPB4 SSF1 TIF6 TUB3 URB1 UTP10 UTP20 UTP22 YGL036W YTM1
    View Details Ho Y, et al. (2002) ACO1 ADR1 AYR1 BGL2 BRX1 CBP6 CCT6 CDC14 CIC1 DIM1 DPS1 EBP2 EGD2 ENP1 ERB1 EXG1 FAA1 FPR4 GAR1 GND1 GSP1 GSP2 GUS1 HAS1 HEM15 HRP1 HXT7 KAP104 KTR3 MET6 MRT4 MUB1 NAB2 NDE1 NOC2 NOC3 NOG1 NOP15 NOP16 NOP2 NOP7 NSA1 NUG1 OAC1 PET10 PET9 PGM2 PIB2 PRP43 PSD1 RLP7 RPT4 RRP17 SAH1 SCS2 SEC53 SPB4 SSQ1 TFG2 THI21 TIF6 UBR2 VMA8 YDL063C YHM2 YNL035C YRB1 YTM1
    View Details Qiu et al. (2008) BRX1 DBP7 GAR1 KRR1 MRT4 NIP7 NOP12 NOP13 NOP15 NOP2 NOP4 NUG1 PXR1 RPF2 RPL15B RPL18A, RPL18B RPL19B, RPL19A RPL27A RPL7B RPS22A SOF1 UTP15 UTP4 UTP9 YBL028C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run BOI1 Sample boi 1 with ha tag from october 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data MRT4 and NOP56 Huh WK, et al. (2003)
    View Data MRT4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..236] PSI-BLAST 71.626727 Ribosomal protein L10


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle