Protein Overview: UTP4

General Information:
Name(s) found:	UTP4 / YDR324C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|915001\|gb\|AAB64760.1\| Ydr324cp [Saccharomyces cerevisiae] [NCBI NR] gi\|6320531\|ref\|NP_010611.1\| Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA; Utp4p [Saccharomyces cerevisiae] [NCBI NR] gi\|59800441\|sp\|Q06679.1\|UTP4_YEAST RecName: Full=U3 small nucleolar RNA-associated protein 4; Short=U3 snoRNA-associated protein 4; AltName: Full=U three protein 4; AltName: Full=t-UTP4; AltName: Full=U3 protein 4 required for transcription [NCBI NR] pir\|\|S59790 hypothetical protein YDR324c - yeast (Saccharomyces cerevisiae) [NCBI NR] U3 small nucleolar RNA-associated protein 4 OS=Saccharomyces cerevisiae GN=UTP4 PE=1 SV=1 [Swiss-Prot] UTP4 U3 snoRNP protein [mips] Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; member of t-Utp subcomplex involved with transcription of 35S rRNA transcript [SGD] YDR324C, Chr IV from 1114425-1116755, reverse complement [yeast_orfs2] Chr IV from 1114425-1116755, reverse complement [yeastorf3.fasta] Chr IV from 1116755-1114425, reverse complement [yeastorf5.fasta] >Q06679 (Q06679) Similar to G-protein beta subunits [4932.FASTACCERV.txt] UTP4 SGDID:S0002732, Chr IV from 1116756-1114426, reverse complement, Verified ORF [yeastflysequest.fasta] UTP4 SGDID:S0002732, Chr IV from 1116758-1114428, reverse complement, Verified ORF [10112005cervSGD.fasta] Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA [Saccharomyces cerevisiae]gi\|915001\|gb\|AAB64760.1\| Ydr324cp [Saccharomyces cerevisiae]gi\|2131430\|pir\|\|S59790 hypot [nrdb_11152004_Chlamydomonas] (Q06679) Ydr324cp [cerv4932.FASTAC] UTP4 SGDID:S000002732, Chr IV from 1116758-1114428, reverse complement, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] UTP4 SGDID:S000002732, Chr IV from 1116760-1114430, reverse complement, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" [yeast-contam.fasta] UTP4 SGDID:S000002732, Chr IV from 1116761-1114431, reverse complement, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] UTP4 SGDID:S000002732, Chr IV from 1116761-1114431, reverse complement, Verified ORF, "Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; member [yeast-200209-contam.fasta] Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA; Utp4p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Ydr324cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] U3 small nucleolar RNA-associated protein 4 (U3 snoRNA-associated protein 4) [nr-271106-contam.fasta] UTP4 SGDID:S000002732, Chr IV from 1116761-1114431, reverse complement, Verified ORF, "Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; member of t-Utp subcomplex involved with transcription of 35S rRNA transcript" [yeast-bovrabprots.fasta] [chemostatdb.fasta] U3 small nucleolar RNA-associated protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UTP4 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] UTP4 SGDID:S000002732, Chr IV from 1116763-1114433, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; member of t-Utp subcomplex involved with transcription of 35S rRNA transcript" [yeast-030211-contam.fasta] UTP4 SGDID:S000002732, Chr IV from 1116763-1114433, Genome Release 64-2-1, reverse complement, Verified ORF, "Subunit of U3-containing 90S preribosome and SSU processome complexes; involved in production of 18S rRNA and assembly of small ribosomal subunit; member of t-Utp subcomplex involved with transcription of 35S rRNA transcript; Small Subunit processome is also known as SSU processome" [20141208_orf_trans.fasta] YDR324C SGDID:S000002732, Chr IV from 1116763-1114433, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; member of t-Utp subcomplex involved with transcription of 35S rRNA transcript" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	776 amino acids
Gene Ontology:
Cellular Component:	small nucleolar ribonucleoprotein complex [IPI]
Biological Process:	maturation of SSU-rRNA [IMP][IPI] ribosome biogenesis [RCA]
Molecular Function:	snoRNA binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSLLSVLK EKSRSLKIRN KPVKMTSQER MIVHRCRFVD FTPATITSLA FSHKSNINKL  60
   61 TPSDLRLAIG RSNGNIEIWN PRNNWFQEMV IEGGKDRSIE GLCWSNVNGE SLRLFSIGGS 120
  121 TVVTEWDLAT GLPLRNYDCN SGVIWSISIN DSQDKLSVGC DNGTVVLIDI SGGPGVLEHD 180
  181 TILMRQEARV LTLAWKKDDF VIGGCSDGRI RIWSAQKNDE NMGRLLHTMK VDKAKKESTL 240
  241 VWSVIYLPRT DQIASGDSTG SIKFWDFQFA TLNQSFKAHD ADVLCLTTDT DNNYVFSAGV 300
  301 DRKIFQFSQN TNKSQKNNRW VNSSNRLLHG NDIRAICAYQ SKGADFLVSG GVEKTLVINS 360
  361 LTSFSNGNYR KMPTVEPYSK NVLVNKEQRL VVSWSESTVK IWTMGTDSST EQNYKLVCKL 420
  421 TLKDDQNIST CSLSPDGQVL VVGRPSTTKV FHLQPVGNKL KVTKLDNDLL LRTSTKLVKF 480
  481 IDNSKIVICS CEDDVFIVDL ESEEDEKPQE VELLEVTSTK SSIKVPYINR INHLEVDQNI 540
  541 AVISRGCGVV DILDLKARIS KPLARLNNFI TAVHINTSRK SVVVITADNK IYEFNMNLNS 600
  601 EAENEDSESV LTQWSKNNTD NLPKEWKTLK ENCVGIFSDI ENSSRLWFWG ATWISRIDFD 660
  661 VDFPINKRRK QKKRTHEGLT ITDESNFMND EEDDEDDDID MEISENLNVL LNQGNKIKST 720
  721 DVQRNEESSG HFFFTDKYKP LLFVDLISSN ELAIIERNPL TFHSKQKAFI QPKLVF

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		BMS1 DIM1 DIP2 ECM16 EMG1 ENP1 ENP2 IMP3 KRE33 MPP10 NAN1 NOC4 NOP1 NOP14 NOP56 PNO1 POL5 PWP2 RPS13 RRP9 SOF1 UTP10 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP5 UTP6 UTP7 UTP8 UTP9
View Details	(MIPS) Mewes HW, et al. (2004)		DRS1 GAR1 IFH1 NOP1 NPL3 NSR1 POP1 POP2 RAT1 RNT1 RRP3 SBP1 SNM1 SRD1 UTP10 UTP11 UTP13 UTP4 UTP5 UTP6 UTP7 UTP8 UTP9 YME2
View Details	Krogan NJ, et al. (2006)		GFD2 NAN1 POL5 UTP10 UTP15 UTP4 UTP5 UTP8 UTP9
View Details	Gavin AC, et al. (2006)		CDC60 CMS1 DIP2 MRD1 NAN1 NOP58 PNO1 PWP2 ROK1 RRP9 UTP10 UTP13 UTP15 UTP18 UTP21 UTP22 UTP4 UTP6 UTP7 UTP8 UTP9
View Details	Gavin AC, et al. (2002)		ADE4 ASC1 BFR2 BMS1 BRX1 BUD21 CBF5 CFT2 CKA1 CKA2 CKB1 CKB2 CMS1 DBP8 DIA4 DIM1 DIP2 DIS3 ECM16 ECM29 EMG1 ENP1 ENP2 ERO1 ESF1 ESF2 FAP7 FIP1 GCN1 GLC7 HAS1 HCA4 HHF1, HHF2 HSL1 HTA2 IMP3 IMP4 KRE33 KRR1 LCP5 LTV1 MPP10 MRD1 MVD1 NAN1 NOB1 NOC2 NOC4 NOP1 NOP12 NOP14 NOP56 NOP58 NOP6 PAP1 PFS2 PNO1 PRE6 PRE9 PRP43 PTA1 PTI1 PWP2 RCL1 REF2 RML2 RNA14 ROK1 RPP2B RRP12 RRP7 RRP9 RTG2 SAM1 SCL1 SEC21 SLX9 SOF1 SRO9 TIF1, TIF2 TSR1 UTP10 UTP11 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9 YOR059C YSH1
View Details	Ho Y, et al. (2002)		CDC10 HHF1, HHF2 HTB1 HTB2 INO4 MAM33 MSI1 NIP7 PSE1 RAD1 UTP4
View Details	Qiu et al. (2008)		BFR2 BRX1 BUD21 DBP3 DBP6 DBP7 DBP8 DHR2 DIP2 DRS1 ECM16 ENP1 ERB1 GAR1 HCA4 IMP3 JIP5 KRI1 KRR1 MAK11 MAK5 MRD1 MRT4 MTR4 NAN1 NOP1 NOP12 NOP13 NOP15 NOP2 NOP4 NOP7 NSR1 PWP2 PXR1 RNT1 RRB1 RRP5 RRP9 SAS10 SGD1 SNU13 SOF1 SPB4 UTP10 UTP11 UTP13 UTP14 UTP15 UTP18 UTP20 UTP22 UTP4 UTP5 UTP6 UTP7 UTP8 UTP9

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ESF1	No Comments	Hazbun TR, et al. (2003)
View Run	ZDS1	Sample 3 - cpn + atp, from june 2005	McCusker D, et al (2007)
View Run	MLP2	#29 Asynchronous Prep5-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	UTP4 and SPC42	Unpublished Data
View Data	UTP4	Huh WK, et al. (2003)
View Data	UTP4 and NOP56	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..73]	deduced	N/A	No confident structure predictions are available.
2	View Details	[74..166]	PSI-BLAST	79.30103	beta1-subunit of the signal-transducing G protein heterotrimer
3	View Details	[167..504]	PSI-BLAST	96.24799	Tup1, C-terminal domain
4	View Details	[505..692]	MSA	3.485995	View MSA. No confident structure predictions are available.
5	View Details	[693..776]	deduced	N/A	No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: UTP4

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: