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View Structure Prediction Details

Protein: UTP4
Organism: Saccharomyces cerevisiae
Length: 776 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UTP4.

Description E-value Query
Range		 Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
 0.0 [1..684] [855..1479]
gi|17225210 - gi|17225210|gb|AAL37301.1|AF323585_1 beta transducin-like protein HET-D2Y [Podospora anserina]
 0.0 [2..548] [823..1316]

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Predicted Domain #1
Region A:
Residues: [1-73] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSLLSVLK EKSRSLKIRN KPVKMTSQER MIVHRCRFVD FTPATITSLA FSHKSNINKL  60
   61 TPSDLRLAIG RSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
snoRNA binding 6.03079504484743 bayes_pls_golite062009
3.41022148055944 bayes_pls_golite062009
RNA binding 3.0829625416797 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
cytoskeletal protein binding 1.5283366007575 bayes_pls_golite062009
structural molecule activity 1.31060431370834 bayes_pls_golite062009
transcription activator activity 1.23969853550045 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
actin binding 0.794986868016276 bayes_pls_golite062009
transcription repressor activity 0.658573452658359 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
ligase activity 0.280267687917718 bayes_pls_golite062009
tubulin binding 0.194781260474147 bayes_pls_golite062009
transcription corepressor activity 0.182612389752591 bayes_pls_golite062009
microtubule binding 0.167936232702449 bayes_pls_golite062009
mRNA binding 0.0519838181830878 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [74-166] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNIEIWNPRN NWFQEMVIEG GKDRSIEGLC WSNVNGESLR LFSIGGSTVV TEWDLATGLP  60
   61 LRNYDCNSGV IWSISINDSQ DKLSVGCDNG TVV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.30103
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [167-504] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIDISGGPGV LEHDTILMRQ EARVLTLAWK KDDFVIGGCS DGRIRIWSAQ KNDENMGRLL  60
   61 HTMKVDKAKK ESTLVWSVIY LPRTDQIASG DSTGSIKFWD FQFATLNQSF KAHDADVLCL 120
  121 TTDTDNNYVF SAGVDRKIFQ FSQNTNKSQK NNRWVNSSNR LLHGNDIRAI CAYQSKGADF 180
  181 LVSGGVEKTL VINSLTSFSN GNYRKMPTVE PYSKNVLVNK EQRLVVSWSE STVKIWTMGT 240
  241 DSSTEQNYKL VCKLTLKDDQ NISTCSLSPD GQVLVVGRPS TTKVFHLQPV GNKLKVTKLD 300
  301 NDLLLRTSTK LVKFIDNSKI VICSCEDDVF IVDLESEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.24799
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [505-692] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEKPQEVELL EVTSTKSSIK VPYINRINHL EVDQNIAVIS RGCGVVDILD LKARISKPLA  60
   61 RLNNFITAVH INTSRKSVVV ITADNKIYEF NMNLNSEAEN EDSESVLTQW SKNNTDNLPK 120
  121 EWKTLKENCV GIFSDIENSS RLWFWGATWI SRIDFDVDFP INKRRKQKKR THEGLTITDE 180
  181 SNFMNDEE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [693-776] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDEDDDIDME ISENLNVLLN QGNKIKSTDV QRNEESSGHF FFTDKYKPLL FVDLISSNEL  60
   61 AIIERNPLTF HSKQKAFIQP KLVF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle