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Protein Overview: IMP4

General Information:
Name(s) found: IMP4 / YNL075W [SGD]
Description(s) found:
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  • gi|791110|emb|CAA60184.1| unknown [Saccharomyces cerevisiae] [NCBI NR]
  • gi|6324254|ref|NP_014324.1| Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs; Imp4p [Saccharomyces cerevi [NCBI NR]
  • gi|1730744|sp|P53941.1|IMP4_YEAST RecName: Full=U3 small nucleolar ribonucleoprotein protein IMP4; Short=U3 snoRNP protein IMP4; AltName: Full=Interacting with MPP10 protein 4 [NCBI NR]
  • gi|1301963|emb|CAA95949.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S53904 hypothetical protein YNL075w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • U3 small nucleolar ribonucleoprotein protein IMP4 OS=Saccharomyces cerevisiae GN=IMP4 PE=1 SV=1 [Swiss-Prot]
  • IMP4 Component of the U3 small nucleolar ribonucleoprotein [mips]
  • Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs [SGD]
  • IMP4, Chr XIV from 485604-486476 [yeast_orfs2]
  • Chr XIV from 485604-486476 [yeastorf3.fasta]
  • (P53941) U3 small nucleolar ribonucleoprotein protein IMP4 [4932.FASTACCERV.txt]
  • IMP4 SGDID:S0005019, Chr XIV from 485606-486478, Verified ORF [yeastflysequest.fasta]
  • Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs [Saccharomyces cerevisiae]gi|791110|emb|CAA60184.1| unk [nrdb_11152004_Chlamydomonas]
  • IMP4 SGDID:S000005019, Chr XIV from 485608-486480, Verified ORF, "Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4) [nr-271106-contam.fasta]
  • Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs; Imp4p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • IMP4 SGDID:S000005019, Chr XIV from 485609-486481, Verified ORF, "Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta]
  • IMP4 SGDID:S000005019, Chr XIV from 485608-486480, Verified ORF, "Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • IMP4 SGDID:S000005019, Chr XIV from 485609-486481, Verified ORF, "Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs" [SGDyeast.20101221.fasta]
  • U3 small nucleolar ribonucleoprotein protein IMP4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IMP4 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • IMP4 SGDID:S000005019, Chr XIV from 485607-486479, Genome Release 64-1-1, Verified ORF, "Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs" [yeast-030211-contam.fasta]
  • IMP4 SGDID:S000005019, Chr XIV from 485607-486479, Genome Release 64-2-1, Verified ORF, "Component of the SSU processome; SSU processome is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs" [20141208_orf_trans.fasta]
  • YNL075W SGDID:S000005019, Chr XIV from 485607-486479, Genome Release 64-1-1, Verified ORF, "Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 290 amino acids

    Gene Ontology:
    Cellular Component: small-subunit processome [IDALink to PubMed article]
    nuclear outer membrane [TASLink to PubMed article]
    small nucleolar ribonucleoprotein complex [IPILink to PubMed article]
    Biological Process: rRNA modification [TASLink to PubMed article]
    maturation of SSU-rRNA [IPILink to PubMed article]
    ribosome biogenesis [RCALink to PubMed article]
    Molecular Function: rRNA primary transcript binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRRQARERR EYLYRKAQEL QDSQLQQKRQ IIKQALAQGK PLPKELAEDE SLQKDFRYDQ  60
   61 SLKESEEADD LQVDDEYAAT SGIMDPRIIV TTSRDPSTRL SQFAKEIKLL FPNAVRLNRG 120
  121 NYVMPNLVDA CKKSGTTDLV VLHEHRGVPT SLTISHFPHG PTAQFSLHNV VMRHDIINAG 180
  181 NQSEVNPHLI FDNFTTALGK RVVCILKHLF NAGPKKDSER VITFANRGDF ISVRQHVYVR 240
  241 TREGVEIAEV GPRFEMRLFE LRLGTLENKD ADVEWQLRRF IRTANKKDYL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) CBF5 DIP2 ECM16 EMG1 IMP3 IMP4 KRR1 MPP10 NOC4 NOP1 NOP14 RRP9 SOF1 UTP15 UTP18 UTP20 UTP22 UTP6 UTP7
    View Details Gavin AC, et al. (2006) IMP4 RPN2
    View Details Gavin AC, et al. (2002) ADE4 ADH1 ASC1 BEM2 BFR2 BMS1 BRX1 BUD21 CBF5 CFT2 CKA1 CKA2 CKB1 CKB2 CMS1 DBP8 DIA4 DIM1 DIP2 DIS3 ECM16 ECM29 EMG1 ENP1 ENP2 ERO1 ESF1 ESF2 FAP7 FIP1 GCN1 GLC7 HAS1 HCA4 HHF1, HHF2 HRR25 HSL1 HTA2 IMP3 IMP4 KRE33 KRR1 LCP5 LTV1 MPP10 MRD1 MVD1 NAN1 NOB1 NOC2 NOC4 NOP1 NOP12 NOP14 NOP56 NOP58 NOP6 PAP1 PFS2 PNO1 PRE6 PRE9 PRP43 PTA1 PTI1 PWP2 RCL1 REF2 RIO2 RML2 RNA14 ROK1 RPP2B RRP12 RRP7 RRP9 RTG2 SAM1 SCL1 SEC21 SLX9 SNF2 SNF5 SOF1 SRO9 SWI3 TIF1, TIF2 TSR1 UTP10 UTP11 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9 YGR054W YOR059C YSH1
    View Details Qiu et al. (2008) ENP1 FCF1 IMP3 IMP4 MPP10 PWP2 RRP5 UTP23 UTP8 UTP9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen IMP4 SPC72 2 Unpublished Fields Lab Data
    View Screen IMP4 ISC10 2 Unpublished Fields Lab Data
    View Screen IMP4 NBP1 2 Unpublished Fields Lab Data
    View Screen IMP4 KIN3 2 Unpublished Fields Lab Data
    View Screen IMP4 MCM6 2 Unpublished Fields Lab Data
    View Screen IMP4 ARG81 2 Unpublished Fields Lab Data
    View Screen IMP4 GIP1 2 Unpublished Fields Lab Data
    View Screen IMP4 POX1 2 Unpublished Fields Lab Data
    View Screen IMP4 ZDS2 2 Unpublished Fields Lab Data
    View Screen IMP4 YBR137W 2 Unpublished Fields Lab Data
    View Screen IMP4 RSC1 2 Unpublished Fields Lab Data
    View Screen IMP4 TMA23 2 Unpublished Fields Lab Data
    View Screen IMP4 YBR138C 2 Unpublished Fields Lab Data
    View Screen IMP4 ATG7 2 Unpublished Fields Lab Data
    View Screen IMP4 APP1 2 Unpublished Fields Lab Data
    View Screen IMP4 BIT2 2 Unpublished Fields Lab Data
    View Screen IMP4 AIR1 2 Unpublished Fields Lab Data
    View Screen IMP4 LAP3 2 Unpublished Fields Lab Data
    View Screen IMP4 BDF2 2 Unpublished Fields Lab Data
    View Screen IMP4 DPH1 2 Unpublished Fields Lab Data
    View Screen IMP4 TLG2 2 Unpublished Fields Lab Data
    View Screen IMP4 GYP7 2 Unpublished Fields Lab Data
    View Screen IMP4 MAD2 2 Unpublished Fields Lab Data
    View Screen IMP4 SKI7 2 Unpublished Fields Lab Data
    View Screen IMP4 YDR026C 2 Unpublished Fields Lab Data
    View Screen IMP4 LOH1 2 Unpublished Fields Lab Data
    View Screen IMP4 MCA1 2 Unpublished Fields Lab Data
    View Screen IMP4 HMO1 2 Unpublished Fields Lab Data
    View Screen IMP4 UBX6 2 Unpublished Fields Lab Data
    View Screen IMP4 FRT1 2 Unpublished Fields Lab Data
    View Screen IMP4 CBS2 2 Unpublished Fields Lab Data
    View Screen IMP4 BIT61 2 Unpublished Fields Lab Data
    View Screen IMP4 LEE1 2 Unpublished Fields Lab Data
    View Screen IMP4 BFR2 2 Unpublished Fields Lab Data
    View Screen IMP4 GSM1 2 Unpublished Fields Lab Data
    View Screen IMP4 UME1 2 Unpublished Fields Lab Data
    View Screen IMP4 ADA2 2 Unpublished Fields Lab Data
    View Screen IMP4 YJR003C 2 Unpublished Fields Lab Data
    View Screen IMP4 YPR197C 2 Unpublished Fields Lab Data
    View Screen IMP4 MZM1 2 Unpublished Fields Lab Data
    View Screen IMP4 YJR008W 2 Unpublished Fields Lab Data
    View Screen IMP4 ARB1 2 Unpublished Fields Lab Data
    View Screen IMP4 MNS1 2 Unpublished Fields Lab Data
    View Screen IMP4 LSM5 2 Unpublished Fields Lab Data
    View Screen IMP4 IES3 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] deduced N/A No confident structure predictions are available.
    2 View Details [88..290] Pfam 87.017729 No description for PF01945 was found. No confident structure predictions are available.
    3 View Details [177..290] FFAS03 1.84 Crystal Structure of Mil (Mth680), an archaeal Imp4-like protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • aminoacyl-tRNA ligase activity
    		•  3.58650371779212 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  3.58624422951947 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  3.58624422951947 bayes_pls_golite062009
  • ligase activity
    		•  2.71574082295198 bayes_pls_golite062009
  • proline-tRNA ligase activity
    		•  2.35871952544841 bayes_pls_golite062009
  • binding
    		•  1.73857064375258 bayes_pls_golite062009
  • catalytic activity
    		•  0.902495165806215 bayes_pls_golite062009
  • protein binding
    		•  0.358563180490135 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle