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Protein Overview: ADR1

General Information:
Name(s) found: ADR1 / YDR216W [SGD]
Description(s) found:
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  • pir||A24534 regulatory protein ADR1 - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|6320422|ref|NP_010502.1| Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization; Ad [NCBI NR]
  • gi|56757368|sp|P07248.2|ADR1_YEAST RecName: Full=Regulatory protein ADR1 [NCBI NR]
  • gi|224966|prf||1204267A ADR1 gene [NCBI NR]
  • Regulatory protein ADR1 OS=Saccharomyces cerevisiae GN=ADR1 PE=1 SV=2 [Swiss-Prot]
  • ADR1 Zinc-finger transcription factor [mips]
  • Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization [SGD]
  • ADR1, Chr IV from 895026-898997 [yeast_orfs2]
  • Chr IV from 895026-898997 [yeastorf3.fasta]
  • ADR1 SGDID:S0002624, Chr IV from 895027-898998, Verified ORF [yeastflysequest.fasta]
  • ADR1 SGDID:S0002624, Chr IV from 895029-899000, Verified ORF [10112005cervSGD.fasta]
  • Adr1p [Saccharomyces cerevisiae]gi|83042|pir||A24534 regulatory protein ADR1 - yeast (Saccharomyces cerevisiae)gi|224966|prf||1204267A ADR1 gene [nrdb_11152004_Chlamydomonas]
  • ADR1 SGDID:S000002624, Chr IV from 895029-899000, Verified ORF, "Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, gly [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • ADR1 SGDID:S000002624, Chr IV from 895031-899002, Verified ORF, "Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, gly [yeast-contam.fasta]
  • ADR1 SGDID:S000002624, Chr IV from 895032-899003, Verified ORF, "Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, gly [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization; Adr1p [Saccharomyces cerevisia [nr-271106-contam.fasta]
  • Regulatory protein ADR1 [nr-271106-contam.fasta]
  • ADR1 gene [nr-271106-contam.fasta]
  • ADR1 SGDID:S000002624, Chr IV from 895032-899003, Verified ORF, "Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization" [yeast-bovrabprots.fasta]
  • ADR1 SGDID:S000002624, Chr IV from 895031-899002, Verified ORF, "Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization" [yeast-contam_custom.fasta]
  • [chemostatdb.fasta]
  • Regulatory protein ADR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADR1 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • ADR1 SGDID:S000002624, Chr IV from 895035-899006, Genome Release 64-1-1, Verified ORF, "Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization" [yeast-030211-contam.fasta]
  • ADR1 SGDID:S000002624, Chr IV from 895035-899006, Genome Release 64-2-1, Verified ORF, "Carbon source-responsive zinc-finger transcription factor; required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization" [20141208_orf_trans.fasta]
  • YDR216W SGDID:S000002624, Chr IV from 895035-899006, Genome Release 64-1-1, Verified ORF, "Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 1323 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IPILink to PubMed article][ISSLink to PubMed article]
    Biological Process: regulation of carbohydrate metabolic process [IGILink to PubMed article][IPILink to PubMed article]
    transcription [IGILink to PubMed article][IPILink to PubMed article]
    peroxisome organization [IMPLink to PubMed article]
    negative regulation of transcription from RNA polymerase II promoter by glucose [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANVEKPNDC SGFPVVDLNS CFSNGFNNEK QEIEMETDDS PILLMSSSAS RENSNTFSVI  60
   61 QRTPDGKIIT TNNNMNSKIN KQLDKLPENL RLNGRTPSGK LRSFVCEVCT RAFARQEHLK 120
  121 RHYRSHTNEK PYPCGLCNRC FTRRDLLIRH AQKIHSGNLG ETISHTKKVS RTITKARKNS 180
  181 ASSVKFQTPT YGTPDNGNFL NRTTANTRRK ASPEANVKRK YLKKLTRRAS FSAQSASSYA 240
  241 LPDQSSLEQH PKDRVKFSTP ELVPLDLKNP ELDSSFDLNM NLDLNLNLDS NFNIALNRSD 300
  301 SSGSTMNLDY KLPESANNYT YSSGSPTRAY VGANTNSKNA SFNDADLLSS SYWIKAYNDH 360
  361 LFSVSESDET SPMNSELNDT KLIVPDFKST IHHLKDSRSS SWTVAIDNNS NNNKVSDNQP 420
  421 DFVDFQELLD NDTLGNDLLE TTAVLKEFEL LHDDSVSATA TSNEIDLSHL NLSNSPISPH 480
  481 KLIYKNKEGT NDDMLISFGL DHPSNREDDL DKLCNMTRDV QAIFSQYLKG EESKRSLEDF 540
  541 LSTSNRKEKP DSGNYTFYGL DCLTLSKISR ALPASTVNNN QPSHSIESKL FNEPMRNMCI 600
  601 KVLRYYEKFS HDSSESVMDS NPNLLSKELL MPAVSELNEY LDLFKNNFLP HFPIIHPSLL 660
  661 DLDLDSLQRY TNEDGYDDAE NAQLFDRLSQ GTDKEYDYEH YQILSISKIV CLPLFMATFG 720
  721 SLHKFGYKSQ TIELYEMSRR ILHSFLETKR RCRSTTVNDS YQNIWLMQSL ILSFMFALVA 780
  781 DYLEKIDSSL MKRQLSALCS TIRSNCLPTI SANSEKSINN NNEPLTFGSP LQYIIFESKI 840
  841 RCTLMAYDFC QFLKCFFHIK FDLSIKEKDV ETIYIPDNES KWASESIICN GHVVQKQNFY 900
  901 DFRNFYYSFT YGHLHSIPEF LGSSMIYYEY DLRKGTKSHV FLDRIDTKRL ERSLDTSSYG 960
  961 NDNMAATNKN IAILIDDTII LKNNLMSMRF IKQIDRSFTE KVRKGQIAKI YDSFLNSVRL1020
 1021 NFLKNYSVEV LCEFLVALNF SIRNISSLYV EEESDCSQRM NSPELPRIHL NNQALSVFNL1080
 1081 QGYYYCFILI IKFLLDFEAT PNFKLLRIFI ELRSLANSIL LPTLSRLYPQ EFSGFPDVVF1140
 1141 TQQFINKDNG MLVPGLSANE HHNGASAAVK TKLAKKINVE GLAMFINEIL VNSFNDTSFL1200
 1201 NMEDPIRNEF SFDNGDRAVT DLPRSAHFLS DTGLEGINFS GLNDSHQTVS TLNLLRYGEN1260
 1261 HSSKHKNGGK GQGFAEKYQL SLKYVTIAKL FFTNVKENYI HCHMLDKMAS DFHTLENHLK1320
 1321 GNS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ACC1 ACH1 ADH2 ADR1 ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3 ATP3 AYR1 BBC1 BGL2 BMH1 BNI1 BNR1 BOI2 CBP6 CCT3 CDC39 CDC53 COP1 CPA2 CRM1 CSR2 CYK3 DEF1 DOP1 DUR1,2 ECM29 ECM33 ENP1 FAA1 FAA4 FOL2 GAL3 GAL7 GAR1 GCD11 GCN1 GFA1 GND1 GSP1 GSY2 GUS1 HEM15 HRP1 HRT1 HYP2 IDH1 IDH2 IMH1 ISA2 KAP104 KAP122 KCS1 KTR3 LSC1 LST8 LYS12 MCM4 MCM7 MDH1 MDN1 MET18 MKT1 MMS1 MRT4 MYO2 NAB2 NDE1 NGL2 NTH1 OAC1 PET10 PET9 PFK1 PHO86 PMA2 POR1 PRB1 PSD1 PYC1 PYC2 REG1 RET1 RET2 RPA135 RPA190 RPA49 RPB5 RPC19 RPC25 RPC34 RPC40 RPC82 RPN1 RPN12 RPN3 RPO26 RPO31 RPT4 RRP3 RVS167 SEC21 SEC26 SEC27 SEC28 SIP1 SLC1 SOK1 SRY1 STI1 STU1 SVL3 TBS1 TFG2 TFP1 TPS1 TRP3 TSA2 UBI4 VMA8 VPS13 YAR009C YBT1 YDL063C YER138C YFL042C YFR017C YGP1 YHM2 YHR112C YIL028W YJR029W YKU80 YLR035C-A YML020W YNL035C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PPT1 ADR1 2 Uetz P, et al. (2000)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ADR1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..100] PSI-BLAST 112.440336 ZIF268
    2 View Details [101..159] PSI-BLAST 328.741366 ADR1
    3 View Details [160..265] PSI-BLAST 58.29073 Ying-yang 1 (yy1, zinc finger domain)
    4 View Details [266..419] MSA 7.692996 View MSA. No confident structure predictions are available.
    5 View Details [420..822] deduced N/A No confident structure predictions are available.
    6 View Details [823..1323] MSA 1.077 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle