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Protein Overview: SLC1

General Information:
Name(s) found: SLC1 / YDL052C [SGD]
Description(s) found:
Found 32 descriptions.
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  • 1-acyl-sn-glycerol-3-phosphate acyltransferase, catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; enzymatic activity detected in lipid particles and microsomes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 303 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDALink to PubMed article]
    Biological Process: sphingolipid biosynthetic process [IMPLink to PubMed article]
    Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVIGRFLYY LRSVLVVLAL AGCGFYGVIA SILCTLIGKQ HLAQWITARC FYHVMKLMLG  60
   61 LDVKVVGEEN LAKKPYIMIA NHQSTLDIFM LGRIFPPGCT VTAKKSLKYV PFLGWFMALS 120
  121 GTYFLDRSKR QEAIDTLNKG LENVKKNKRA LWVFPEGTRS YTSELTMLPF KKGAFHLAQQ 180
  181 GKIPIVPVVV SNTSTLVSPK YGVFNRGCMI VRILKPISTE NLTKDKIGEF AEKVRDQMVD 240
  241 TLKEIGYSPA INDTTLPPQA IEYAALQHDK KVNKKIKNEP VPSVSISNDV NTHNEGSSVK 300
  301 KMH

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2002) ADH1 CCT4 CSE1 DHH1 DUG1 ECM29 FKS1 GCN1 GCN20 GFA1 IDH2 KAP123 KTR3 MIR1 RGR1 SAM1 SEC7 SLC1 SRV2 YHR020W
    View Details Ho Y, et al. (2002) ACC1 ADR1 ATP3 BGL2 CBP6 CCT3 COP1 CPA2 DEF1 FAA1 FOL2 FRS2 GAL7 GCD11 GCN3 GUF1 HXT7 IDH1 KTR3 LSC1 LST8 LYS12 MCX1 MKT1 MNN9 NDE1 NPA3 PET10 PET9 PHO86 POR1 RPN12 RRP3 SIP1 SLC1 STI1 TRP3 TRP5 VAN1 VMA8 VPS8 WBP1 YBT1 YHM2 YKU80 YML020W
    View Details Qiu et al. (2008) ATF1 DGA1 EHT1 SLC1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SLC1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..217] PSI-BLAST 3.0 Glycerol-3-phosphate (1)-acyltransferase
    2 View Details [218..303] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle