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Protein Overview: EHT1

General Information:
Name(s) found: EHT1 / YBR177C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Acyl-coenzymeA:ethanol O-acyltransferase that plays a minor role in medium-chain fatty acid ethyl ester biosynthesis; possesses short-chain esterase activity; localizes to lipid particles and the mitochondrial outer membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 451 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed article]
    Biological Process: lipid metabolic process [IMPLink to PubMed article]
    medium-chain fatty acid metabolic process [IMPLink to PubMed article]
    Molecular Function: hydrolase activity, acting on ester bonds [IDALink to PubMed article]
    serine hydrolase activity [IDALink to PubMed article][RCALink to PubMed article]
    alcohol O-acetyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEVSKWPAI NPFHWGYNGT VSHIVGENGS IKLHLKDNKE QVDFDEFANK YVPTLKNGAQ  60
   61 FKLSPYLFTG ILQTLYLGAA DFSKKFPVFY GREIVKFSDG GVCTADWLID SWKKDYEFDQ 120
  121 STTSFDKKKF DKDEKATHPE GWPRLQPRTR YLKDNELEEL REVDLPLVVI LHGLAGGSHE 180
  181 PIIRSLAENL SRSGRFQVVV LNTRGCARSK ITTRNLFTAY HTMDIREFLQ REKQRHPDRK 240
  241 LYAVGCSFGA TMLANYLGEE GDKSPLSAAA TLCNPWDLLL SAIRMSQDWW SRTLFSKNIA 300
  301 QFLTRTVQVN MGELGVPNGS LPDHPPTVKN PSFYMFTPEN LIKAKSFKST REFDEVYTAP 360
  361 ALGFPNAMEY YKAASSINRV DTIRVPTLVI NSRDDPVVGP DQPYSIVEKN PRILYCRTDL 420
  421 GGHLAYLDKD NNSWATKAIA EFFTKFDELV V

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ATF1 AYR1 DGA1 EHT1 ERG9 SLC1 YJU3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data EHT1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] deduced N/A No confident structure predictions are available.
    2 View Details [110..451] PSI-BLAST 47.522879 Epoxide hydrolase, N-terminal domain; Mammalian epoxide hydrolase, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • lipase activity
    		•  0.849473630399459 bayes_pls_golite062009
  • carboxylesterase activity
    		•  0.424330502936163 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.264183693934251 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle