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Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion. The hydrolysis of an incorrectly aminoacylated tRNA. Catalysis of the reaction: acetylcholine + H2O = choline + acetate. Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a fatty acid anion. Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol. Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate. Catalysis of the reaction: 6-acetyl-D-glucose + H2O = D-glucose + acetate. Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone. Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate. Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate. Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate. Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate. Catalysis of the reaction: acetylsalicylate + H2O = salicylate + acetate. Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate. Catalysis of the reaction: 6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate. Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine. Catalysis of the reaction: 11-cis-retinyl palmitate + H2O = 11-cis-retinol + palmitate. Catalysis of the reaction: pectin + n H2O = n methanol + pectate. Catalysis of the reaction: digallate + H2O = 2 gallate. Catalysis of the reaction: cephalosporin C + H2O = deacetylcephalosporin C + acetate. Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate. Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate. Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol. Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide. Catalysis of the reaction: D-aminoacyl-tRNA = D-amino acid + tRNA. Hydrolysis of the removal of D-amino acids from residues in charged tRNA. Catalysis of the reaction: orsellinate depside + H2O = 2 orsellinate. Catalysis of the reaction: cetraxate benzyl ester + H2O = cetraxate + benzyl alcohol. Catalysis of the reaction: pheophytin + H2O = phytol + pheophorbide. Catalysis of the reaction: 2-pyrone-4,6-dicarboxylate + H2O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate. Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate. Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate. Catalysis of the reaction: L-arabinono-1,4-lactone + H2O = L-arabinonate. Catalysis of the reaction: atropine + H2O = tropine + tropate. Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+. Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid. Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H2O = 2-ethylhexyl phthalate + 2-ethylhexan-1-ol. Catalysis of the reaction: triacetate lactone + H2O = triacetate. Catalysis of the reaction: deoxylimonate + H2O = deoxylimononic acid D-ring-lactone. Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms. Catalysis of the reaction: cutin + H2O = cutin monomers. Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x = 1-5. Catalysis of the reaction: (R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H2O = 2 (R)-3-hydroxybutanoate. Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x = 1-5. Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate. Catalysis of the reaction: sinapoylcholine + H2O = sinapate + choline. Catalysis of the deacetylation of xylans and xylo-oligosaccharides. Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion. Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid. Catalysis of the reaction: H2O + polyneuridine aldehyde = methanol + CO2 + 16-epivellosimine. Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a. Catalysis of the hydrolysis of any ester bond. Catalysis of the reaction: 1-phosphatidyl-D-myo-inositol + H2O = 1-acylglycerophosphoinositol + a carboxylate. Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone. Catalysis of the reaction: 4-pyridoxolactone + H2O = 4-pyridoxate. Catalysis of the reaction: chlorogenate + H2O = caffeate + quinate. Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate. Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide. Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate. Catalysis of the reaction: L-rhamnono-1,4-lactone + H2O = L-rhamnonate. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. Catalysis of the reaction: oxaloacetate 4-methyl ester + H2O = oxaloacetate + methanol. Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol. Catalysis of the reaction: testololactone + H2O = testolate. Catalysis of the reaction: 4-methylumbelliferyl acetate + H2O = acetate + 4-methylumbelliferone. Catalysis of the reaction: H2O + 5-(4-acetoxybut-1-ynyl)-2-2'-bithiophene = acetate + 5-(4-hydroxybut-1-ynyl)-2,2'-bithiophene. Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. Catalysis of the reaction L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate. Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol. Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan. Catalysis of the reaction: H2O + 2-acetyl-1-alkyl-sn-glycerol = acetate + 1-alkyl-sn-glycerol. Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol. Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol. Catalysis of the reaction: H2O + 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene = acetate + 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene. Catalysis of the reaction: dihydrocoumarin + H2O = melilotate. Catalysis of the reaction: D-arabinono-1,4-lactone + H2O = D-arabinonate. Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro). Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates. Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr). Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate and 17-O-acetylnorajmaline + H2O = norajmaline + acetate. Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate. Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala). Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. Catalysis of the reaction: phorbol 12,13-dibutanoate + H2O = phorbol 13-butanoate + butanoate. Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate. Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate. Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group. Catalysis of the reaction methyl indole-3-acetate (MeIAA) + H2O = indole-3-acetate (IAA)+ methanol. Catalysis of the reaction methyl salicylate (MeSA) + H2O = salicylic acid (SA)+ methanol. Catalysis of the reaction methyl jasmonate (MeJA) + H2O = jasmonate (JA)+ methanol. Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate, triacylglycerol + H2O = diacylglycerol + a carboxylate, and monoacylglycerol + H2O = glycerol + a carboxylate. Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: carboxylesterase activity
Acc: GO:0004091
Aspect: Molecular Function
Desc: Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion.
Synonyms:
  • GO:0016789
  • nonspecific carboxylesterase activity
  • alpha-carboxylesterase activity
  • carboxyesterase activity
  • cocaine esterase activity
  • B-esterase activity
  • vitamin A esterase
  • esterase B
  • carboxylate esterase activity
  • carboxylic acid esterase activity
  • esterase A
  • carboxylic-ester hydrolase activity
  • procaine esterase activity
  • GO:0004302
  • carboxylic ester hydrolase activity
  • triacetin esterase
  • serine esterase activity
  • Ali-esterase activity
  • GO:0004759
  • carboxyl ester hydrolase activity
  • carboxylic esterase activity
Proteins in PDR annotated with:
   This term: 264 [Search]
   Term or descendants: 894 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004091 - carboxylesterase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle