Protein Overview: PHO86

General Information:
Name(s) found:	PHO86 / YJL117W [SGD]
Description(s) found: Found 31 descriptions. SHOW ALL	Endoplasmic reticulum (ER) resident protein required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles [SGD]
Organism:	Saccharomyces cerevisiae
Length:	311 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IDA]
Biological Process:	phosphate transport [IMP] secretory pathway [IMP] protein folding [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVQQRKKKE GRKSDKNAPS VPQVDASLDK PLDIDAPPTI YSVNLKPEYG TAALNLSADF  60
   61 IRQEQALANK YLFFHPVILV VLTIGLLIYL TPRIVFPIRN TGSVAGWFYQ LARINKKVVL 120
  121 SGLVFTAIGA SFLFTLLSRV SDSYFKSKIN QLVGSKGEKV FGINLNDLVA RHETKDPVVN 180
  181 NTHIIVYRET PIALISLAPN MTLSTDENLV MSVTTVGCRR VYVKSGIIED LIDWAMLHSK 240
  241 NIRSSGKYGE TMKLLIDVYS FDSTLKEILK KKGFTYIQSI RVSENRLLGG LFGVKKELWG 300
  301 LQFHFKAEHK D

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		GPD1 PDR5 PHO86 PMA1 PMT1 SSH1 WBP1 YGR266W
View Details	Ho Y, et al. (2002)		ACC1 ADR1 ATP3 CCT3 COP1 CPA2 DEF1 FOL2 GAL7 IDH1 LSC1 LST8 LYS12 NUP120 NUP84 PHO86 POR1 PRB1 RET2 RPN12 RRP3 SEC21 SEC26 SEC27 SEC28 SIP1 SLC1 STI1 TRP3 YBT1 YKU80 YML020W

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	INP54	PHO86	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	PHO86	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..311]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2