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Protein Overview: SRY1

General Information:
Name(s) found: SRY1 / YKL218C [SGD]
Description(s) found:
Found 30 descriptions.
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  • 3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required in the presence of hydroxyaspartate; highly similar to mouse serine racemase (Srr) but has no serine racemase activity [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 326 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: cellular amino acid derivative catabolic process [IMPLink to PubMed article]
    Molecular Function: threo-3-hydroxyaspartate ammonia-lyase activity [IDALink to PubMed article]
    [NOT]serine racemase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIVPTYGDVL DASNRIKEYV NKTPVLTSRM LNDRLGAQIY FKGENFQRVG AFKFRGAMNA  60
   61 VSKLSDEKRS KGVIAFSSGN HAQAIALSAK LLNVPATIVM PEDAPALKVA ATAGYGAHII 120
  121 RYNRYTEDRE QIGRQLAAEH GFALIPPYDH PDVIAGQGTS AKELLEEVGQ LDALFVPLGG 180
  181 GGLLSGSALA ARSLSPGCKI FGVEPEAGND GQQSFRSGSI VHINTPKTIA DGAQTQHLGE 240
  241 YTFAIIRENV DDILTVSDQE LVKCMHFLAE RMKVVVEPTA CLGFAGALLK KEELVGKKVG 300
  301 IILSGGNVDM KRYATLISGK EDGPTI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ADR1 DOP1 ECM29 KAP122 MET18 RPA135 RPA190 RPC40 RPO31 SRY1 YER138C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #34 Asynchronous SPB prep Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..21]
    [47..156]    		 PSI-BLAST 506.67837 Allosteric threonine deaminase N-terminal domain; Allosteric threonine deaminase C-terminal domain
    2 View Details [22..46]
    [157..326]    		 PSI-BLAST 506.67837 Allosteric threonine deaminase N-terminal domain; Allosteric threonine deaminase C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • threonine racemase activity
    		•  4.44340924206787 bayes_pls_golite062009
  • threonine synthase activity
    		•  3.59927532963055 bayes_pls_golite062009
  • cysteine synthase activity
    		•  3.57860549303214 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  3.33109959091277 bayes_pls_golite062009
  • catalytic activity
    		•  2.38994231321972 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.99526226543975 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • binding
    		•  0.557628798477604 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009
  • protein binding
    		•  0.066947056585999 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle