Protein Overview: NSA2

General Information:
Name(s) found:	NSA2 / YER126C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|731511\|sp\|P40078.1\|NSA2_YEAST RecName: Full=Ribosome biogenesis protein NSA2; AltName: Full=NOP7-associated protein 2 [NCBI NR] gi\|6320973\|ref\|NP_011052.1\| Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA; Nsa2p [Saccharomyces cerevisiae] [NCBI NR] gi\|603365\|gb\|AAC03224.1\| Yer126cp [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S43218 hypothetical protein YER126c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|51013835\|gb\|AAT93211.1\| YER126C [Saccharomyces cerevisiae] [NCBI NR] Uncharacterized protein YER126C - Saccharomyces cerevisiae (Baker's yeast) [Swiss-Prot] Ribosome biogenesis protein NSA2 OS=Saccharomyces cerevisiae GN=NSA2 PE=1 SV=1 [Swiss-Prot] NSA2 Protein involved in biogenesis of ribosomal large subunit [mips] Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA [SGD] KRE32, Chr V from 413390-414175, reverse complement [yeast_orfs2] Chr V from 413390-414175, reverse complement [yeastorf3.fasta] Chr V from 414175-413390, reverse complement [yeastorf5.fasta] (P40078) Hypothetical 29.7 kDa protein in RSP5-LCP5 intergenic region [4932.FASTACCERV.txt] NSA2 SGDID:S0000928, Chr V from 414175-413390, reverse complement, Verified ORF [yeastflysequest.fasta] Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis [Saccharomyces cerevisiae]gi\|51013835\|gb\|AAT93211.1\| YER126C [Saccharomyces cerevisiae]gi\|603365\|gb\|AAC03224.1\| Yer126cp [Saccharomyces cerevisiae]gi\|731511\|sp\|P40 [nrdb_11152004_Chlamydomonas] NSA2 SGDID:S000000928, Chr V from 414175-413390, reverse complement, Verified ORF, "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] NSA2 SGDID:S000000928, Chr V from 414175-413390, reverse complement, Verified ORF, "Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] Uncharacterized protein YER126C [nr-271106-contam.fasta] YER126C [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Yer126cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; Nsa2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Ribosome biogenesis protein NSA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NSA2 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] NSA2 SGDID:S000000928, Chr V from 414179-413394, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA" [yeast-030211-contam.fasta] NSA2 SGDID:S000000928, Chr V from 414179-413394, Genome Release 64-2-1, reverse complement, Verified ORF, "Protein constituent of 66S pre-ribosomal particles; contributes to processing of the 27S pre-rRNA" [20141208_orf_trans.fasta] TR749\|c0_g1_i1\|g.497 ORF TR749\|c0_g1_i1\|g.497 TR749\|c0_g1_i1\|m.497 type:complete len:262 (+) TR749\|c0_g1_i1:98-883(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YER126C SGDID:S000000928, Chr V from 414179-413394, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_7848\|g.5552 ORF asmbl_7848\|g.5552 asmbl_7848\|m.5552 type:complete len:262 (+) asmbl_7848:103-888(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_7825\|g.4817 ORF ID=asmbl_7825\|g.4817 ID=asmbl_7825\|m.4817 type:complete len:262 (+) ID=asmbl_7825:103-888(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	261 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] preribosome, large subunit precursor [IDA]
Biological Process:	ribosomal large subunit biogenesis [IMP][IPI] ribosome biogenesis [RCA] processing of 27S pre-rRNA [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQNDYIERH IKQHGKRLDH EERKRKREAR ESHKISERAQ KLTGWKGKQF AKKRYAEKVS  60
   61 MRKKIKAHEQ SKVKGSSKPL DTDGDALPTY LLDREQNNTA KAISSSIKQK RLEKADKFSV 120
  121 PLPKVRGISE EEMFKVIKTG KSRSKSWKRM ITKHTFVGEG FTRRPVKMER IIRPSALRQK 180
  181 KANVTHPELG VTVFLPILAV KKNPQSPMYT QLGVLTKGTI IEVNVSELGM VTAGGKVVWG 240
  241 KYAQVTNEPD RDGCVNAVLL V

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		ARX1 BUD20 CIC1 DBP10 DRS1 ERB1 HAS1 IPI3 LHP1 MRT4 NOC2 NOG1 NOG2 NOP15 NOP7 NSA1 NSA2 NUG1 PUF6 RIX1 RLP7 RPF1 RPF2 RSA4 SDA1 TIF6 YTM1
View Details	Gavin AC, et al. (2006)		ARX1 BUD20 FPR4 IPI3 MRT4 NIP7 NOG1 NOG2 NOP2 NSA2 NUG1 RIX1 RPF2 RSA4 SDA1 TIF6
View Details	Gavin AC, et al. (2002)		ARX1 BEM2 BMS1 BRX1 BUD20 CIC1 CLU1 CYR1 CYS4 DBP10 DBP9 DCP2 DRS1 EBP2 ERB1 FPR4 GCN1 HAS1 HDA1 HER1 HIS3 INP2 IPI1 IPI3 KRE33 LHP1 LOC1 LSG1 MAK21 MAK5 MDN1 MIS1 MRT4 NAP1 NIP1 NIP7 NMD3 NOC2 NOC3 NOG1 NOG2 NOP1 NOP12 NOP15 NOP16 NOP2 NOP4 NOP56 NOP7 NSA1 NSA2 NUG1 PRT1 PUF6 REI1 RIX1 RIX7 RLP24 RLP7 RPA135 RPA190 RPF1 RPF2 RPG1 RPP2B RPT6 RRP1 RRP12 RSA3 RSA4 RTR1 SDA1 SEC7 SKI2 SNU13 SPB1 SPB4 SSF1 TIF6 TUB3 URB1 UTP10 UTP20 UTP22 YGL036W YTM1
View Details	Ho Y, et al. (2002)		AAC3 AFG2 ALB1 ARP4 ARX1 ASA1 ATG17 ATG29 ATP3 BRX1 BUD20 CDC33 CIC1 CIS1 CKB1 COX6 CYS4 EHD3 FET4 FOL2 FYV4 GAR1 GRH1 HAP2 HAP5 HHF1, HHF2 HTA1 HTB1 HTB2 IPP1 LHP1 LOC1 MAM33 MNP1 MRPS16 MTQ1 NAP1 NIP7 NMD3 NMD5 NOC2 NOG1 NOP1 NOP12 NOP13 NOP16 NOP2 NOP56 NOP7 NSA1 NSA2 NUG1 PHO84 POL5 PRP43 PSE1 PUF6 PWP1 RHR2 RIX1 RRP1 RSM24 RSM25 SAH1 SAP190 SPE3 SSK2 TIF1, TIF2 TIF6 YBL044W YPL009C YRA1 YRA2 YTM1
View Details	Qiu et al. (2008)		NSA2 RPL27A RPL27B RPL4A RPL4B RPP2B TSR2

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	BOI1	Sample boi 1 with ha tag from october 2005	McCusker D, et al (2007)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	NSA2	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..114]	MSA	3.016968	View MSA. No confident structure predictions are available.
2	View Details	[115..261]	deduced	N/A	No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: NSA2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: