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Protein Overview: NSA2

General Information:
Name(s) found: NSA2 / YER126C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 261 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    preribosome, large subunit precursor [IDALink to PubMed article]
    Biological Process: ribosomal large subunit biogenesis [IMPLink to PubMed article][IPILink to PubMed article]
    ribosome biogenesis [RCALink to PubMed article]
    processing of 27S pre-rRNA [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQNDYIERH IKQHGKRLDH EERKRKREAR ESHKISERAQ KLTGWKGKQF AKKRYAEKVS  60
   61 MRKKIKAHEQ SKVKGSSKPL DTDGDALPTY LLDREQNNTA KAISSSIKQK RLEKADKFSV 120
  121 PLPKVRGISE EEMFKVIKTG KSRSKSWKRM ITKHTFVGEG FTRRPVKMER IIRPSALRQK 180
  181 KANVTHPELG VTVFLPILAV KKNPQSPMYT QLGVLTKGTI IEVNVSELGM VTAGGKVVWG 240
  241 KYAQVTNEPD RDGCVNAVLL V

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARX1 BUD20 CIC1 DBP10 DRS1 ERB1 HAS1 IPI3 LHP1 MRT4 NOC2 NOG1 NOG2 NOP15 NOP7 NSA1 NSA2 NUG1 PUF6 RIX1 RLP7 RPF1 RPF2 RSA4 SDA1 TIF6 YTM1
    View Details Gavin AC, et al. (2006) ARX1 BUD20 FPR4 IPI3 MRT4 NIP7 NOG1 NOG2 NOP2 NSA2 NUG1 RIX1 RPF2 RSA4 SDA1 TIF6
    View Details Gavin AC, et al. (2002) ARX1 BEM2 BMS1 BRX1 BUD20 CIC1 CLU1 CYR1 CYS4 DBP10 DBP9 DCP2 DRS1 EBP2 ERB1 FPR4 GCN1 HAS1 HDA1 HER1 HIS3 INP2 IPI1 IPI3 KRE33 LHP1 LOC1 LSG1 MAK21 MAK5 MDN1 MIS1 MRT4 NAP1 NIP1 NIP7 NMD3 NOC2 NOC3 NOG1 NOG2 NOP1 NOP12 NOP15 NOP16 NOP2 NOP4 NOP56 NOP7 NSA1 NSA2 NUG1 PRT1 PUF6 REI1 RIX1 RIX7 RLP24 RLP7 RPA135 RPA190 RPF1 RPF2 RPG1 RPP2B RPT6 RRP1 RRP12 RSA3 RSA4 RTR1 SDA1 SEC7 SKI2 SNU13 SPB1 SPB4 SSF1 TIF6 TUB3 URB1 UTP10 UTP20 UTP22 YGL036W YTM1
    View Details Ho Y, et al. (2002) AAC3 AFG2 ALB1 ARP4 ARX1 ASA1 ATG17 ATG29 ATP3 BRX1 BUD20 CDC33 CIC1 CIS1 CKB1 COX6 CYS4 EHD3 FET4 FOL2 FYV4 GAR1 GRH1 HAP2 HAP5 HHF1, HHF2 HTA1 HTB1 HTB2 IPP1 LHP1 LOC1 MAM33 MNP1 MRPS16 MTQ1 NAP1 NIP7 NMD3 NMD5 NOC2 NOG1 NOP1 NOP12 NOP13 NOP16 NOP2 NOP56 NOP7 NSA1 NSA2 NUG1 PHO84 POL5 PRP43 PSE1 PUF6 PWP1 RHR2 RIX1 RRP1 RSM24 RSM25 SAH1 SAP190 SPE3 SSK2 TIF1, TIF2 TIF6 YBL044W YPL009C YRA1 YRA2 YTM1
    View Details Qiu et al. (2008) NSA2 RPL27A RPL27B RPL4A RPL4B RPP2B TSR2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run BOI1 Sample boi 1 with ha tag from october 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data NSA2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] MSA 3.016968 View MSA. No confident structure predictions are available.
    2 View Details [115..261] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle