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Protein Overview: UTP7

General Information:
Name(s) found: UTP7 / YER082C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 554 amino acids

    Gene Ontology:
    Cellular Component: nuclear outer membrane [IMPLink to PubMed article]
    small nucleolar ribonucleoprotein complex [IPILink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    rRNA processing [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: snoRNA binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGHKKNGHRR QIKERENQNK FERSTYTNNA KNNHTQTKDK KLRAGLKKID EQYKKAVSSA  60
   61 AATDYLLPES NGYLEPENEL EKTFKVQQSE IKSSVDVSTA NKALDLSLKE FGPYHIKYAK 120
  121 NGTHLLITGR KGHVASMDWR KGQLRAELFL NETCHSATYL QNEQYFAVAQ KKYTFIYDHE 180
  181 GTELHRLKQH IEARHLDFLP YHYLLVTAGE TGWLKYHDVS TGQLVSELRT KAGPTMAMAQ 240
  241 NPWNAVMHLG HSNGTVSLWS PSMPEPLVKL LSARGPVNSI AIDRSGYYMA TTGADRSMKI 300
  301 WDIRNFKQLH SVESLPTPGT NVSISDTGLL ALSRGPHVTL WKDALKLSGD SKPCFGSMGG 360
  361 NPHRNTPYMS HLFAGNKVEN LGFVPFEDLL GVGHQTGITN LIVPGAGEAN YDALELNPFE 420
  421 TKKQRQEQEV RTLLNKLPAD TITLDPNSIG SVDKRSSTIR LNAKDLAQTT MDANNKAKTN 480
  481 SDIPDVKPDV KGKNSGLRSF LRKKTQNVID ERKLRVQKQL DKEKNIRKRN HQIKQGLISE 540
  541 DHKDVIEEAL SRFG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BFR2 BMS1 DIM1 DIP2 ECM16 EMG1 ENP1 ENP2 IMP3 IMP4 KRE33 KRR1 MPP10 NAN1 NOC4 NOP1 NOP14 NOP56 PNO1 PWP2 ROK1 RRP12 RRP9 SOF1 UTP10 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9
    View Details (MIPS) Mewes HW, et al. (2004) DRS1 GAR1 IFH1 NOP1 NPL3 NSR1 POP1 POP2 RAT1 RNT1 RRP3 SBP1 SNM1 SRD1 UTP10 UTP11 UTP13 UTP4 UTP5 UTP6 UTP7 UTP8 UTP9 YME2
    View Details Gavin AC, et al. (2006) CMS1 DIP2 ENP1 ENP2 KRE33 KRR1 MRD1 NAN1 NOC4 NOP14 NOP58 PNO1 PWP2 ROK1 RRP9 UTP10 UTP13 UTP15 UTP18 UTP21 UTP22 UTP4 UTP6 UTP7 UTP8 UTP9
    View Details Gavin AC, et al. (2002) ADE4 ADH1 ASC1 BEM2 BFR2 BMS1 BRX1 BUD21 CBF5 CFT2 CKA1 CKA2 CKB1 CKB2 CMS1 DBP8 DIA4 DIM1 DIP2 DIS3 ECM16 ECM29 EMG1 ENP1 ENP2 ERO1 ESF1 ESF2 FAP7 FIP1 GCN1 GLC7 HAS1 HCA4 HHF1, HHF2 HRR25 HSL1 HTA2 IMP3 IMP4 KRE33 KRR1 LCP5 LTV1 MPP10 MRD1 MVD1 NAN1 NOB1 NOC2 NOC4 NOP1 NOP12 NOP14 NOP56 NOP58 NOP6 PAP1 PFS2 PNO1 PRE6 PRE9 PRP43 PTA1 PTI1 PWP2 RCL1 REF2 RIO2 RML2 RNA14 ROK1 RPP2B RRP12 RRP7 RRP9 RTG2 SAM1 SCL1 SEC21 SLX9 SNF2 SNF5 SOF1 SRO9 SWI3 TIF1, TIF2 TSR1 UTP10 UTP11 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9 YGR054W YOR059C YSH1
    View Details Ho Y, et al. (2002) AAC3 BRX1 BUD3 CCT2 CCT3 CCT6 CIN8 CLU1 CYS4 GND1 GSP1 HIR1 HTB1 KRE33 MNP1 NAN1 NOP12 NOP56 POL5 PUF6 RLI1 RPF2 RRP12 RVB1 SPT2 SRP1 SSD1 SSF1 STE23 SUP45 TIF4631 TMA19 UTP10 UTP22 UTP7
    View Details Qiu et al. (2008) BUD21 DIP2 DRS1 ENP1 GAR1 HAS1 IFH1 IMP3 LCP5 MRD1 NAN1 NHP2 NOP1 NOP14 NSR1 PWP2 RRP5 RRP9 SAS10 SBP1 SNU13 SOF1 UTP11 UTP13 UTP14 UTP15 UTP18 UTP20 UTP21 UTP22 UTP4 UTP5 UTP6 UTP7 UTP8 UTP9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PXR1 UTP7 1 Unpublished Fields Lab Data
    View Screen NAS2 UTP7 1 Unpublished Fields Lab Data
    View Screen PPG1 UTP7 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..92] deduced N/A No confident structure predictions are available.
    2 View Details [93..448] PSI-BLAST 82.522879 beta1-subunit of the signal-transducing G protein heterotrimer
    3 View Details [449..554] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • snoRNA binding
    		•  6.03079504484743 bayes_pls_golite062009
    		• 3.41022148055944 bayes_pls_golite062009
  • RNA binding
    		•  3.0829625416797 bayes_pls_golite062009
  • binding
    		•  1.83286470399158 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.25687092973217 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.20712373307552 bayes_pls_golite062009
  • structural molecule activity
    		•  1.20572493724069 bayes_pls_golite062009
  • protein binding
    		•  0.987581964031738 bayes_pls_golite062009
  • DNA binding
    		•  0.711274653406079 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.523052412917759 bayes_pls_golite062009
  • transcription factor activity
    		•  0.243992994917491 bayes_pls_golite062009
  • mRNA binding
    		•  0.0519838181830878 bayes_pls_golite062009
  • ligase activity
    		•  0.00971558442368137 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle