Protein Overview: TFC7

General Information:
Name(s) found:	TFC7 / YOR110W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6324684\|ref\|NP_014753.1\| One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; Tfc7p [Saccharomyce [NCBI NR] gi\|59800397\|sp\|Q12415.1\|TFC7_YEAST RecName: Full=Transcription factor tau 55 kDa subunit; AltName: Full=TFIIIC 55 kDa subunit; AltName: Full=Transcription factor C subunit 7 [NCBI NR] pir\|\|S61668 hypothetical protein YOR110w - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1420297\|emb\|CAA99308.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|1164955\|emb\|CAA64030.1\| YOR3234w [Saccharomyces cerevisiae] [NCBI NR] Transcription factor tau 55 kDa subunit OS=Saccharomyces cerevisiae GN=TFC7 PE=1 SV=1 [Swiss-Prot] TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa [mips] One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes [SGD] >Q12415 (Q12415) YOR3234W from chromosome XV [4932.FASTACCERV.txt] Chr XV from 528941-530248 [hmr_yeast5_DM3-1_pombe.fasta] Chr XV from 528940-530247 [yeastorf3.fasta] TFC7, Chr XV from 528940-530247 [yeast_orfs2] TFC7 SGDID:S0005636, Chr XV from 528941-530248, Verified ORF [yeastflysequest.fasta] Tfc7p [Saccharomyces cerevisiae]gi\|1420297\|emb\|CAA99308.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|1164955\|emb\|CAA64030.1\| YOR3234w [Saccharomyces cerevisiae]gi\|2132058\|pir\|\|S61668 hypothetical protein YOR110w - yeast (Saccharomyces cerevi [nrdb_11152004_Chlamydomonas] (Q12415) YOR3234w protein (S.cerevisiae chromosome XV reading frame ORF YOR110w) [cerv4932.FASTAC] TFC7 SGDID:S000005636, Chr XV from 528941-530248, Verified ORF, "One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA a [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] TFC7 SGDID:S000005636, Chr XV from 528942-530249, Verified ORF, "One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA a [yeast-contam.fasta] YOR3234w [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Transcription factor tau 55 kDa subunit (TFIIIC 55 kDa subunit) [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; Tfc7p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] TFC7 SGDID:S000005636, Chr XV from 528942-530249, Verified ORF, "One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Transcription factor tau 55 kDa subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TFC7 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] TFC7 SGDID:S000005636, Chr XV from 528941-530248, Genome Release 64-1-1, Verified ORF, "One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes" [yeast-030211-contam.fasta] TFC7 SGDID:S000005636, Chr XV from 528941-530248, Genome Release 64-2-1, Verified ORF, "RNA pol III transcription initiation factor complex (TFIIIC) subunit; part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; TFC7 has a paralog, YNL108C, that arose from the whole genome duplication" [20141208_orf_trans.fasta] TR7470\|c0_g1_i1\|g.5196 ORF TR7470\|c0_g1_i1\|g.5196 TR7470\|c0_g1_i1\|m.5196 type:complete len:436 (+) TR7470\|c0_g1_i1:113-1420(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] YOR110W SGDID:S000005636, Chr XV from 528941-530248, Genome Release 64-1-1, Verified ORF, "One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] ID=asmbl_2405\|g.1584 ORF ID=asmbl_2405\|g.1584 ID=asmbl_2405\|m.1584 type:complete len:436 (+) ID=asmbl_2405:112-1419(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	435 amino acids
Gene Ontology:
Cellular Component:	transcription factor TFIIIC complex [TAS]
Biological Process:	transcription initiation from RNA polymerase III promoter [TAS]
Molecular Function:	RNA polymerase III transcription factor activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVNTIYIAR HGYRSNWLPE GPYPDPLTGI DSDVPLAEHG VQQAKELAHY LLSLDNQPEA  60
   61 AFASPFYRCL ETVQPIAKLL EIPVYLERGI GEWYRPDRKP VIPVPAGYEI LSKFFPGVIS 120
  121 QEWDSTLTPN EKGETEQEMY MRFKKFWPLF IERVEKEYPN VECILLVTHA ASKIALGMSL 180
  181 LGYDNPRMSL NENGDKIRSG SCSLDKYEIL KKSYDTIDET DDQTSFTYIP FSDRKWVLTM 240
  241 NGNTEFLSSG EEMNWNFDCV AEAGSDADIK KRQMTKKTSS PIPEADDQTE VETVYISVDI 300
  301 PSGNYKERTE IAKSAILQYS GLETDAPLFR IGNRLYEGSW ERLVGTELAF PNAAHVHKKT 360
  361 AGLLSPTEEN ETTNAGQSKG SSTANDPNIQ IQEEDVGLPD STNTSRDHTG DKEEVQSEKI 420
  421 YRIKERIVLS NVRPM

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		TFC1 TFC3 TFC4 TFC6 TFC7 TFC8
View Details	(MIPS) Mewes HW, et al. (2004)		TFC1 TFC3 TFC4 TFC6 TFC7
View Details	Krogan NJ, et al. (2006)		TFC1 TFC3 TFC4 TFC6 TFC7 TFC8
View Details	Gavin AC, et al. (2006)		TFC1 TFC3 TFC4 TFC6 TFC7 TFC8
View Details	Gavin AC, et al. (2002)		ADE5,7 AHA1 ATP11 CAF130 CAF40 CCR4 CCT6 CDC36 CDC39 COP1 FAS2 GCN1 HHF1, HHF2 IOC3 ISW1 ISW2 ITC1 MOT1 MOT2 NOT3 NOT5 NPL6 PDC1 POL1 POL12 POP2 PRI1 PRI2 REB1 RFA1 RFX1 RNR2 RPC34 RPC40 RPO31 RSC2 RSC3 RSC58 RSC8 RVB2 SAM1 SEC27 SFH1 STH1 STO1 TAF1 TFC1 TFC3 TFC4 TFC6 TFC7 TFC8 TFP1 TOP1 VPS1 YBR090C-A, NHP6B YRA1
View Details	Ho Y, et al. (2002)		ATP3 AVO1 CCT5 CLU1 DHH1 DPB2 FUN12 GAL7 GPH1 IDH1 ILV2 MET16 MKK2 NOG2 NPA3 PDX1 PHO85 PUF3 RPN12 SIS1 SLX1 SRP54 STI1 TEM1 TFC7 VMA8 YER077C YGR266W YKR051W YKU80 YLR271W YPR003C
View Details	Qiu et al. (2008)		BDP1 PZF1 TFB5 TFC1 TFC3 TFC4 TFC6 TFC7 TFC8

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	CEP3	sample cbf3 from feb 2005	Sandall S, et all (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	TFC7	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..233]	PSI-BLAST	44.522879	Phosphoglycerate mutase
2	View Details	[234..435]	MSA	5.047977	View MSA. No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: TFC7

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: