YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter. Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. A protein complex, distinct from RNA polymerase, that associates with DNA at promoters or at cis-acting regulatory sequences, by direct binding or by interaction with other DNA-binding polypeptides or complexes, and regulates transcription. A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity. A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: transcription factor TFIIIC complex
Acc: GO:0000127
Aspect: Cellular Component
Desc: A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species.
Proteins in PDR annotated with:
   This term: 23 [Search]
   Term or descendants: 23 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000127 - transcription factor TFIIIC complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle