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Protein Overview: SOF1

General Information:
Name(s) found: SOF1 / YLL011W [SGD]
Description(s) found:
Found 31 descriptions.
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  • Essential protein required for biogenesis of 40S (small) ribosomal subunit; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 489 amino acids

    Gene Ontology:
    Cellular Component: nuclear outer membrane [TASLink to PubMed article]
    nucleolus [IDALink to PubMed article]
    small nuclear ribonucleoprotein complex [TASLink to PubMed article]
    small nucleolar ribonucleoprotein complex [IPILink to PubMed article][TASLink to PubMed article]
    Biological Process: rRNA modification [TASLink to PubMed article]
    maturation of SSU-rRNA [IPILink to PubMed article]
    Molecular Function: snoRNA binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIKTIKRSA DDYVPVKSTQ ESQMPRNLNP ELHPFERARE YTKALNATKL ERMFAKPFVG  60
   61 QLGYGHRDGV YAIAKNYGSL NKLATGSADG VIKYWNMSTR EEFVSFKAHY GLVTGLCVTQ 120
  121 PRFHDKKPDL KSQNFMLSCS DDKTVKLWSI NVDDYSNKNS SDNDSVTNEE GLIRTFDGES 180
  181 AFQGIDSHRE NSTFATGGAK IHLWDVNRLK PVSDLSWGAD NITSLKFNQN ETDILASTGS 240
  241 DNSIVLYDLR TNSPTQKIVQ TMRTNAICWN PMEAFNFVTA NEDHNAYYYD MRNLSRSLNV 300
  301 FKDHVSAVMD VDFSPTGDEI VTGSYDKSIR IYKTNHGHSR EIYHTKRMQH VFQVKYSMDS 360
  361 KYIISGSDDG NVRLWRSKAW ERSNVKTTRE KNKLEYDEKL KERFRHMPEI KRISRHRHVP 420
  421 QVIKKAQEIK NIELSSIKRR EANERRTRKD MPYISERKKQ IVGTVHKYED SGRDRKRRKE 480
  481 DDKRDTQEK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BMS1 DIP2 ECM16 EMG1 ENP1 ENP2 IMP3 IMP4 KRE33 KRR1 MPP10 NAN1 NOC4 NOP1 NOP14 NOP56 PWP2 RRP9 SOF1 UTP10 UTP13 UTP15 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9
    View Details Gavin AC, et al. (2002) ADE4 ADH1 ASC1 BEM2 BFR2 BMS1 BRX1 BUD21 CBF5 CFT2 CKA1 CKA2 CKB1 CKB2 CMS1 DBP8 DIA4 DIM1 DIP2 DIS3 ECM16 ECM29 EMG1 ENP1 ENP2 ERO1 ESF1 ESF2 FAP7 FIP1 GCN1 GLC7 HAS1 HCA4 HHF1, HHF2 HRR25 HSL1 HTA2 IMP3 IMP4 KRE33 KRR1 LCP5 LTV1 MPP10 MRD1 MVD1 NAN1 NOB1 NOC2 NOC4 NOP1 NOP12 NOP14 NOP56 NOP58 NOP6 PAP1 PFS2 PNO1 PRE6 PRE9 PRP43 PTA1 PTI1 PWP2 RCL1 REF2 RIO2 RML2 RNA14 ROK1 RPP2B RRP12 RRP7 RRP9 RTG2 SAM1 SCL1 SEC21 SLX9 SNF2 SNF5 SOF1 SRO9 SWI3 TIF1, TIF2 TSR1 UTP10 UTP11 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9 YGR054W YOR059C YSH1
    View Details Ho Y, et al. (2002) AHA1 AHP1 ARF1 CCT2 CCT3 CCT5 CCT6 GND1 GPG1 HEF3 HTB1 KRE33 LHS1 MGE1 MGT1 RIP1 RRP5 SEC27 SOF1 TCP1 TMA19 UBR1 YHR033W
    View Details Qiu et al. (2008) BFR2 BUD21 DBP3 DIP2 DRS1 ENP1 GAR1 IMP3 KRR1 LCP5 MRD1 MRT4 NAN1 NHP2 NOP12 NOP14 NOP15 NOP4 NSR1 NUG1 PRP43 PWP2 PXR1 RRP3 RRP5 RRP9 SAS10 SBP1 SMD3 SNU13 SOF1 UTP10 UTP11 UTP13 UTP14 UTP15 UTP20 UTP21 UTP22 UTP4 UTP5 UTP6 UTP7 UTP8 UTP9

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SOF1 and NOP56 Huh WK, et al. (2003)
    View Data SOF1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] ORFEUS 11.8 No description for 1scgB was found.
    2 View Details [109..489] PSI-BLAST 124.30103 Tup1, C-terminal domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle