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Protein Overview: RIP1

General Information:
Name(s) found: RIP1 / YEL024W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Ubiquinol-cytochrome-c reductase, a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 215 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article][IPILink to PubMed article]
    mitochondrial respiratory chain complex III [IDALink to PubMed articleLink to PubMed article]
    Biological Process: mitochondrial electron transport, ubiquinol to cytochrome c [IDALink to PubMed article]
    aerobic respiration [IMPLink to PubMed article]
    Molecular Function: ubiquinol-cytochrome-c reductase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGIRSSVKT CFKPMSLTSK RLISQSLLAS KSTYRTPNFD DVLKENNDAD KGRSYAYFMV  60
   61 GAMGLLSSAG AKSTVETFIS SMTATADVLA MAKVEVNLAA IPLGKNVVVK WQGKPVFIRH 120
  121 RTPHEIQEAN SVDMSALKDP QTDADRVKDP QWLIMLGICT HLGCVPIGEA GDFGGWFCPC 180
  181 HGSHYDISGR IRKGPAPLNL EIPAYEFDGD KVIVG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) COB COR1 CYT1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1
    View Details Ho Y, et al. (2002) AHA1 AHP1 ARF1 GND1 GPG1 HEF3 HTB1 LHS1 MGE1 MGT1 RIP1 SEC27 SOF1 TMA19 UBR1 YHR033W
    View Details Qiu et al. (2008) AAC1 AAC3 ATP1 ATP14 ATP15 ATP16 ATP17 ATP18 ATP19 ATP2 ATP20 ATP3 ATP4 ATP5 ATP6 ATP7 ATP8 COB COR1 COX1 COX13 COX2 COX3 COX4 COX5A COX5B COX6 COX7 COX8 COX9 CYB2 CYC1 CYT1 INH1 MCR1 OLI1 POR1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1 SDH1 SDH2 SDH3 SDH4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RIP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] PSI-BLAST 1149.69897 ISP subunit of the mitochondrial cytochrome bc1-complex, watersoluble domain; Iron-sulfur subunit (ISP) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane region
    2 View Details [89..215] PSI-BLAST 1149.69897 ISP subunit of the mitochondrial cytochrome bc1-complex, watersoluble domain; Iron-sulfur subunit (ISP) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane region

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquinol-cytochrome-c reductase activity
    		•  12.5243667017255 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
    		•  12.5243667017255 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  9.125468664417 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  6.56410033542443 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  6.40889163290296 bayes_pls_golite062009
  • oxidoreductase activity
    		•  6.05060612159037 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  5.79350583896014 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  5.52425708699797 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.31511996363681 bayes_pls_golite062009
  • electron carrier activity
    		•  5.20213585732279 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.88364619884033 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  4.66567624087954 bayes_pls_golite062009
  • binding
    		•  1.1265044642485 bayes_pls_golite062009
  • catalytic activity
    		•  0.746741393172769 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  0.71220774812099 bayes_pls_golite062009
  • metal cluster binding
    		•  0.71220774812099 bayes_pls_golite062009
  • protein binding
    		•  0.439276074643623 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.67

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle