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View Structure Prediction Details

Protein: RIP1
Organism: Saccharomyces cerevisiae
Length: 215 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RIP1.

Description E-value Query
Range
Subject
Range
RIP1 - Ubiquinol-cytochrome-c reductase, a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 c...
UCRI_YEAST - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 20450...
3.0E-58 [1..215] [1..215]
UCRI_RAT - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Rattus norvegicus GN=Uqcrfs1 PE=1 SV=2
2.0E-55 [5..214] [34..254]
UCRI_BOVIN - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Bos taurus GN=UQCRFS1 PE=1 SV=3
3.0E-54 [5..214] [52..272]
UQCRFS1 - ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
gi|39939354 - gi|39939354|gb|AAR32728.1| ubiquinol-cytochrome c oxidoreductase subunit 9 and Rieske iron sulfur pr...
gi|123981876 - gi|123981876|gb|ABM82767.1| ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 [synt...
UCRI_GORGO - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Gorilla gorilla gorilla GN=UQCRFS1 PE=3 SV=...
2.0E-53 [4..214] [51..272]
UCRI_MOUSE - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Mus musculus GN=Uqcrfs1 PE=1 SV=1
3.0E-53 [5..214] [52..272]
UCRI3_TOBAC - Cytochrome b-c1 complex subunit Rieske-3, mitochondrial OS=Nicotiana tabacum PE=2 SV=1
6.0E-53 [2..215] [43..268]
UCRI_SOLTU - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Solanum tuberosum GN=FES1 PE=1 SV=1
4.0E-52 [3..215] [41..265]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGIRSSVKT CFKPMSLTSK RLISQSLLAS KSTYRTPNFD DVLKENNDAD KGRSYAYFMV  60
   61 GAMGLLSSAG AKSTVETFIS SMTATADV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1149.69897
Match: 1ezvE_
Description: ISP subunit of the mitochondrial cytochrome bc1-complex, watersoluble domain; Iron-sulfur subunit (ISP) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane region
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquinol-cytochrome-c reductase activity 12.5243667017255 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor 12.5243667017255 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 9.125468664417 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 6.56410033542443 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 6.40889163290296 bayes_pls_golite062009
oxidoreductase activity 6.05060612159037 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 5.79350583896014 bayes_pls_golite062009
cation transmembrane transporter activity 5.52425708699797 bayes_pls_golite062009
ion transmembrane transporter activity 5.31511996363681 bayes_pls_golite062009
electron carrier activity 5.20213585732279 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.88364619884033 bayes_pls_golite062009
substrate-specific transporter activity 4.66567624087954 bayes_pls_golite062009
binding 1.1265044642485 bayes_pls_golite062009
catalytic activity 0.746741393172769 bayes_pls_golite062009
iron-sulfur cluster binding 0.71220774812099 bayes_pls_golite062009
metal cluster binding 0.71220774812099 bayes_pls_golite062009
protein binding 0.439276074643623 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [89-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAMAKVEVNL AAIPLGKNVV VKWQGKPVFI RHRTPHEIQE ANSVDMSALK DPQTDADRVK  60
   61 DPQWLIMLGI CTHLGCVPIG EAGDFGGWFC PCHGSHYDIS GRIRKGPAPL NLEIPAYEFD 120
  121 GDKVIVG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1149.69897
Match: 1ezvE_
Description: ISP subunit of the mitochondrial cytochrome bc1-complex, watersoluble domain; Iron-sulfur subunit (ISP) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane region
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle