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Protein Overview: SDH3

General Information:
Name(s) found: SDH3 / YKL141W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Cytochrome b subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 198 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex II [TASLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: tricarboxylic acid cycle [TASLink to PubMed article]
    mitochondrial electron transport, succinate to ubiquinone [TASLink to PubMed article]
    Molecular Function: succinate dehydrogenase (ubiquinone) activity [IMPLink to PubMed article][TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAMMVKLGL NKSALLLKPS AFSRAAALSS SRRLLFNTAR TNFLSTSPLK NVASEMNTKA  60
   61 AIAEEQILNK QRAKRPISPH LTIYQPQLTW YLSSLHRISL VLMGLGFYLF TILFGVSGLL 120
  121 GLGLTTEKVS NWYHQKFSKI TEWSIKGSFA YLFAIHYGGA IRHLIWDTAK ELTLKGVYRT 180
  181 GYALIGFTAV LGTYLLTL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) SDH1 SDH2 SDH3 SDH4
    View Details Qiu et al. (2008) COB COR1 COX1 COX13 COX2 COX3 COX4 COX5A COX5B COX6 COX7 COX8 COX9 CYT1 MCR1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1 SDH1 SDH2 SDH3 SDH4

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..53] deduced N/A No confident structure predictions are available.
    2 View Details [54..198] Pfam 59.468521 Succinate dehydrogenase cytochrome b subunit No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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