Protein Overview: SDH3

General Information:
Name(s) found:	SDH3 / YKL141W [SGD]
Description(s) found: Found 28 descriptions. SHOW ALL	Cytochrome b subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain [SGD]
Organism:	Saccharomyces cerevisiae
Length:	198 amino acids
Gene Ontology:
Cellular Component:	mitochondrial respiratory chain complex II [TAS] mitochondrion [IDA]
Biological Process:	tricarboxylic acid cycle [TAS] mitochondrial electron transport, succinate to ubiquinone [TAS]
Molecular Function:	succinate dehydrogenase (ubiquinone) activity [IMP][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAMMVKLGL NKSALLLKPS AFSRAAALSS SRRLLFNTAR TNFLSTSPLK NVASEMNTKA  60
   61 AIAEEQILNK QRAKRPISPH LTIYQPQLTW YLSSLHRISL VLMGLGFYLF TILFGVSGLL 120
  121 GLGLTTEKVS NWYHQKFSKI TEWSIKGSFA YLFAIHYGGA IRHLIWDTAK ELTLKGVYRT 180
  181 GYALIGFTAV LGTYLLTL

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		SDH1 SDH2 SDH3 SDH4
View Details	Qiu et al. (2008)		COB COR1 COX1 COX13 COX2 COX3 COX4 COX5A COX5B COX6 COX7 COX8 COX9 CYT1 MCR1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1 SDH1 SDH2 SDH3 SDH4

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	CTF13	SDH3	1	Unpublished Fields Lab Data
View Screen	RAD1	SDH3	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..53]	deduced	N/A	No confident structure predictions are available.
2	View Details	[54..198]	Pfam	59.468521	Succinate dehydrogenase cytochrome b subunit No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2