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Protein Overview: COX13

General Information:
Name(s) found: COX13 / YGL191W [SGD]
Description(s) found:
Found 34 descriptions.
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  • Subunit VIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 129 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial respiratory chain complex IV [IPILink to PubMed article]
    Biological Process: aerobic respiration [IMPLink to PubMed article]
    Molecular Function: cytochrome-c oxidase activity [IPILink to PubMed article]
    enzyme regulator activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRQCAKRYA SSLPPNALKP AFGPPDKVAA QKFKESLMAT EKHAKDTSNM WVKISVWVAL  60
   61 PAIALTAVNT YFVEKEHAEH REHLKHVPDS EWPRDYEFMN IRSKPFFWGD GDKTLFWNPV 120
  121 VNRHIEHDD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) COX1 COX12 COX13 COX2 COX3 COX4 COX5A COX6 COX7 COX8 COX9
    View Details Qiu et al. (2008) ATP14 ATP15 ATP2 ATP5 ATP6 ATP7 ATP8 COB COR1 COX1 COX13 COX2 COX3 COX4 COX5A COX5B COX6 COX7 COX8 COX9 CYT1 INH1 OLI1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1 SDH2 SDH3 SDH4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen NPA3 COX13 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..129] PSI-BLAST 100.38764 Mitochondrial cytochrome c oxidase subunit VIa

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytochrome-c oxidase activity
    		•  8.55593054200713 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors
    		•  8.55593054200713 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors, oxygen as acceptor
    		•  8.55593054200713 bayes_pls_golite062009
  • heme-copper terminal oxidase activity
    		•  8.33310447684473 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.93709142475202 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  3.42266067775966 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.27737232830687 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.64965096433631 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.41719119401631 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.22093703573522 bayes_pls_golite062009
  • catalytic activity
    		•  0.448769452796145 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.55

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle