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Protein Overview: COP1

Protein Complex Data

  PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
View Details Riffle et al. (2010) (Unpublished Data) COP1 GLO3 RET2 RET3 SEC21 SEC26 SEC27 SEC28
View Details (MIPS) Mewes HW, et al. (2004) ARF1 COP1 RET2 RET3 SEC21 SEC26 SEC27 SEC28
View Details Krogan NJ, et al. (2006) COP1 FCF2 FMP23 LCB5 PIP2 RET2 RET3 SCS2 SEC2 SEC21 SEC26 SEC27 SEC28
View Details Gavin AC, et al. (2006) COP1 RET2 RET3 SEC21 SEC26 SEC27 SEC28
View Details Gavin AC, et al. (2002) AHA1 ATG26 ATP11 BEM2 BUD3 CAF130 CAF40 CCR4 CCT6 CDC36 CDC39 COP1 CYR1 FAS2 GCN1 GLO3 GPT2 HRR25 ILV1 IMG1 IMG2 IML1 MHR1 MOT2 MRH4 MRM1 MRP20 MRP49 MRP7 MRPL1 MRPL10 MRPL13 MRPL16 MRPL17 MRPL19 MRPL20 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL35 MRPL36 MRPL39 MRPL4 MRPL44 MRPL51 MRPL6 MRPL7 MRPL8 NOT3 NOT5 NUG1 PDC1 PGK1 POL1 POL12 POP2 PRI1 PRI2 PRP43 RET2 RET3 ROM2 RTC6 RVB2 SAM1 SCJ1 SEC1 SEC21 SEC26 SEC27 SEC28 SEH1 SIN4 SNF2 SWI3 SYP1 TAF5 TFC7 TFP1 TOS1 UTP20 YDR115W YML6 YRA1
View Details Ho Y, et al. (2002) ACC1 ADH2 ADK1 ADR1 AHC1 ATP3 BEM2 BTN2 CCT2 CCT3 CCT6 CKA1 CLB2 CLU1 COP1 CPA2 CTR1 DEF1 DHH1 DSS1 DUF1 EAP1 ECM29 EDE1 FAR1 FMP40 FOL2 GAL7 GDT1 GFA1 GPH1 GSY1 HSL7 HTB2 IDH1 KEL1 LHS1 LSC1 LST8 LYS12 MAM33 MEH1 NAN1 NIP1 NUG1 PAA1 PHO86 POR1 PRB1 PRP11 PTC3 REP1 RET2 REX2 RFC4 RPG1 RPN12 RPN7 RPT3 RRP3 SEC21 SEC26 SEC27 SEC28 SES1 SHM2 SIP1 SLC1 SLD2 SLN1 SMC3 SRP1 SRV2 SSK2 STI1 SWE1 TCB1 TCP1 TDA10 TFP1 THI22 TIF34 TIF35 TIF4631 TRL1 TRP3 UBI4 UBP15 UBR1 URA7 UTP13 YBT1 YCR076C YGL081W YGR250C YKU80 YML020W
View Details Qiu et al. (2008) ARF1 COP1 GLO3 RET2 RET3 SAR1 SEC13 SEC21 SEC26 SEC27 SEC28 SFB3

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
View Run RPA135 No Comments Schneider, DA, et al. (2006)
View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
View Run BOI1 Sample boi 1 with ha tag from october 2005 McCusker D, et al (2007)
View Run BOI1 Sample boi1 with gst from october 2005 McCusker D, et al (2007)
View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

  PROTEIN(S) PUBLICATION
View Data VPS54 and COP1 Huh WK, et al. (2003)
View Data MTC1 and COP1 Huh WK, et al. (2003)
View Data SYS1 and COP1 Huh WK, et al. (2003)
View Data VPS53 and COP1 Huh WK, et al. (2003)
View Data KEI1 and COP1 Huh WK, et al. (2003)
View Data YMR253C and COP1 Huh WK, et al. (2003)
View Data ARL1 and COP1 Huh WK, et al. (2003)
View Data SEC18 and COP1 Huh WK, et al. (2003)
View Data MON2 and COP1 Huh WK, et al. (2003)
View Data RET2 and COP1 Huh WK, et al. (2003)
View Data AUR1 and COP1 Huh WK, et al. (2003)
View Data NEO1 and COP1 Huh WK, et al. (2003)
View Data COP1 Huh WK, et al. (2003)
View Data AKR1 and COP1 Huh WK, et al. (2003)
View Data SFT2 and COP1 Huh WK, et al. (2003)
View Data APL6 and COP1 Huh WK, et al. (2003)
View Data DOP1 and COP1 Huh WK, et al. (2003)
View Data SEC27 and COP1 Huh WK, et al. (2003)
View Data SEC21 and COP1 Huh WK, et al. (2003)
View Data SEC26 and COP1 Huh WK, et al. (2003)
View Data YIP3 and COP1 Huh WK, et al. (2003)
View Data SEC28 and COP1 Huh WK, et al. (2003)
View Data SGM1 and COP1 Huh WK, et al. (2003)
View Data TVP15 and COP1 Huh WK, et al. (2003)
View Data COG2 and COP1 Huh WK, et al. (2003)
View Data ARL3 and COP1 Huh WK, et al. (2003)
View Data VRG4 and COP1 Huh WK, et al. (2003)
View Data GEA2 and COP1 Huh WK, et al. (2003)
View Data DRS2 and COP1 Huh WK, et al. (2003)
View Data APM3 and COP1 Huh WK, et al. (2003)
View Data TMN3 and COP1 Huh WK, et al. (2003)
View Data YMR010W and COP1 Huh WK, et al. (2003)
View Data COG1 and COP1 Huh WK, et al. (2003)
View Data APS3 and COP1 Huh WK, et al. (2003)
View Data YOL107W and COP1 Huh WK, et al. (2003)
View Data COP1 and COP1 Huh WK, et al. (2003)
View Data SSP120 and COP1 Huh WK, et al. (2003)
View Data BUG1 and COP1 Huh WK, et al. (2003)
View Data APL5 and COP1 Huh WK, et al. (2003)
View Data VPS45 and COP1 Huh WK, et al. (2003)
View Data COP1 and ANP1 Huh WK, et al. (2003)
View Data TVP23 and COP1 Huh WK, et al. (2003)
View Data COG4 and COP1 Huh WK, et al. (2003)
View Data TVP38 and COP1 Huh WK, et al. (2003)
View Data ARF2 and COP1 Huh WK, et al. (2003)
View Data YND1 and COP1 Huh WK, et al. (2003)
View Data SLY1 and COP1 Huh WK, et al. (2003)
View Data STV1 and COP1 Huh WK, et al. (2003)
View Data ARF1 and COP1 Huh WK, et al. (2003)
View Data BSC6 and COP1 Huh WK, et al. (2003)
View Data RBD2 and COP1 Huh WK, et al. (2003)
View Data GLO3 and COP1 Huh WK, et al. (2003)
View Data COG3 and COP1 Huh WK, et al. (2003)
View Data RGP1 and COP1 Huh WK, et al. (2003)
View Data KEX2 and COP1 Huh WK, et al. (2003)
View Data COG5 and COP1 Huh WK, et al. (2003)
View Data YMD8 and COP1 Huh WK, et al. (2003)

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..324] PSI-BLAST 217.211549 Tup1, C-terminal domain
2 View Details [325..443] PSI-BLAST 31.69897 Groucho/tle1, C-terminal domain
3 View Details [444..646] MSA 3.420995 View MSA. No confident structure predictions are available.
4 View Details [647..792] ORFEUS 9.91 Clathrin heavy chain proximal leg segment
5 View Details [793..980] deduced N/A No confident structure predictions are available.
6 View Details [981..1088] ORFEUS 7.21 Hop
7 View Details [1089..1140] ORFEUS 7.21 Hop
8 View Details [1141..1201] deduced N/A No confident structure predictions are available.

Functions predicted (by domain):

# Gene Ontology predictions
1
Term Confidence Notes
  • structural molecule activity
  • 5.05435272846365 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K4 specific)
  • 4.71992275913384 bayes_pls_golite062009
  • 4.71945350582521 bayes_pls_golite062009
  • myosin heavy chain kinase activity
  • 4.33124151198369 bayes_pls_golite062009
  • actin binding
  • 3.86142918698875 bayes_pls_golite062009
  • acetyltransferase activity
  • 3.85374902981345 bayes_pls_golite062009
  • RNA binding
  • 3.77273677738815 bayes_pls_golite062009
  • myosin II binding
  • 3.56132510021228 bayes_pls_golite062009
  • acyltransferase activity
  • 3.35098520158193 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
  • 3.31760161664239 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
  • 3.31615347567536 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
  • 3.25521258308263 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
  • 3.14917998298348 bayes_pls_golite062009
  • cytoskeletal protein binding
  • 3.1056443224755 bayes_pls_golite062009
  • tubulin binding
  • 2.76945430061825 bayes_pls_golite062009
  • microtubule binding
  • 2.72684103222924 bayes_pls_golite062009
  • dynein binding
  • 2.54821997913979 bayes_pls_golite062009
  • binding
  • 2.42570478946173 bayes_pls_golite062009
  • snoRNA binding
  • 2.27164613239345 bayes_pls_golite062009
  • protein binding
  • 2.26925404328312 bayes_pls_golite062009
  • transcription regulator activity
  • 2.10348788067437 bayes_pls_golite062009
  • actin filament binding
  • 2.0735069176589 bayes_pls_golite062009
  • transcription repressor activity
  • 2.03485691549401 bayes_pls_golite062009
  • nucleic acid binding
  • 2.00420268007946 bayes_pls_golite062009
  • histone methyltransferase activity
  • 1.85632145559025 bayes_pls_golite062009
  • dynactin binding
  • 1.85146647785657 bayes_pls_golite062009
  • DNA binding
  • 1.53482914288832 bayes_pls_golite062009
  • protein methyltransferase activity
  • 1.35170368882651 bayes_pls_golite062009
  • transporter activity
  • 1.21549336905926 bayes_pls_golite062009
  • transcription corepressor activity
  • 1.2107661925348 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
  • 1.15313682561559 bayes_pls_golite062009
  • lysine N-methyltransferase activity
  • 1.15313682561559 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
  • 1.15313682561559 bayes_pls_golite062009
  • receptor binding
  • 1.10903984294711 bayes_pls_golite062009
  • mRNA binding
  • 1.05053985350578 bayes_pls_golite062009
  • microtubule plus-end binding
  • 1.01166033978052 bayes_pls_golite062009
  • myosin binding
  • 0.989691178611801 bayes_pls_golite062009
  • receptor activity
  • 0.973153886219821 bayes_pls_golite062009
  • protein transporter activity
  • 0.964340340346761 bayes_pls_golite062009
  • transcription factor activity
  • 0.897833210520351 bayes_pls_golite062009
  • kinase activity
  • 0.807669232329985 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
  • 0.805273887494167 bayes_pls_golite062009
  • molecular transducer activity
  • 0.762533049716683 bayes_pls_golite062009
  • signal transducer activity
  • 0.762533049716683 bayes_pls_golite062009
  • substrate-specific transporter activity
  • 0.734793983890004 bayes_pls_golite062009
  • transcription activator activity
  • 0.724420384084538 bayes_pls_golite062009
  • G-protein-coupled receptor binding
  • 0.710786225826124 bayes_pls_golite062009
  • histone binding
  • 0.685319917508843 bayes_pls_golite062009
  • transcription initiation factor activity
  • 0.656824577987243 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
  • 0.634547834947756 bayes_pls_golite062009
  • glycosaminoglycan binding
  • 0.561837715670207 bayes_pls_golite062009
  • protein kinase activity
  • 0.544118712921054 bayes_pls_golite062009
  • transcription factor binding
  • 0.469377587704245 bayes_pls_golite062009
  • dynein intermediate chain binding
  • 0.443846546939402 bayes_pls_golite062009
  • nucleotidyltransferase activity
  • 0.28606552120995 bayes_pls_golite062009
  • transcription cofactor activity
  • 0.245000508226811 bayes_pls_golite062009
  • structural constituent of cytoskeleton
  • 0.118975415284669 bayes_pls_golite062009
  • protein serine/threonine kinase activity
  • 0.0803897416817422 bayes_pls_golite062009
  • heparin binding
  • 0.0276138170689455 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
  • 0.00585398682921312 bayes_pls_golite062009
  • N-methyltransferase activity
  • 0.00335766408304172 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
  • 1.90408871052739 bayes_pls_golite062009
  • protein binding
  • 1.47118967208188 bayes_pls_golite062009
  • catalytic activity
  • 0.233388920718075 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.




    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle