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Protein Overview: SES1

General Information:
Name(s) found: SES1 / YDR023W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 462 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed articleLink to PubMed article]
    Biological Process: seryl-tRNA aminoacylation [IDALink to PubMed article]
    Molecular Function: serine-tRNA ligase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [NCBI BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDINQFIED KGGNPELIRQ SQKARNASVE IVDEIISDYK DWVKTRFELD ELNKKFNKLQ  60
   61 KDIGLKFKNK EDASGLLAEK EKLTQQKKEL TEKEQQEDKD LKKKVFQVGN IVHPSVVVSN 120
  121 DEENNELVRT WKPEDLEAVG PIASVTGKPA SLSHHEILLR LDGYDPDRGV KICGHRGYFF 180
  181 RNYGVFLNQA LINYGLQFLA AKGYIPLQAP VMMNKELMSK TAQLSEFDEE LYKVIDGEDE 240
  241 KYLIATSEQP ISAYHSGEWF EKPQEQLPIH YVGYSSCFRR EAGSHGKDAW GVFRVHAFEK 300
  301 IEQFVITEPE KSWEEFEKMI SYSEEFYKSL KLPYRIVGIV SGELNNAAAK KYDLEAWFPY 360
  361 QKEYKELVSC SNCTDYQSRN LEIRCGIKKM GDREKKYVHC LNSTLAATQR ALCCILENYQ 420
  421 TEDGLVVPEV LRKYIPGEPE FLPFVNELPK NSTSSKDKKK KN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) DRE2 SES1 TAH18
    View Details Gavin AC, et al. (2002) AEP1 AEP2 ATP22 HRP1 SES1 TSR1
    View Details Ho Y, et al. (2002) AAT2 ABP1 ACH1 ACO1 ADH2 ADH6 ADK1 AFR1 AHP1 AIM41 AIR2 ARC1 ARF1 ARG1 ATP3 ATP4 AVO1 BEM2 BUD14 CAR2 CDC33 CLU1 COF1 COP1 COR1 CPR1 CRZ1 CYR1 CYS4 DCP1 DCP2 DED1 DNM1 DUF1 EDC3 EDE1 EGD1 EGD2 ENP1 ERG13 ERG6 FET4 FOL2 FPR1 FRS2 GAS1 GCN3 GND1 GND2 GPH1 GRX1 GUS1 HEF3 HHF2, HHF1 HRR25 HSP104 HTB2 HXT6 HXT7 HYP2 ILV5 IPP1 KGD2 KRS1 LHS1 LOC1 LPD1 LRO1 LSP1 LTV1 MDH1 MDS3 MET6 MGE1 MRPS35 NIP1 NPL3 NSA1 NTF2 NUG1 OLA1 OYE2 PDC6 PEX19 PFK1 PIL1 PIN4 PMI40 POR1 PRM2 PTC4 PUF3 QCR2 RIO2 RNR2 RPC19 RPG1 RPM2 RSN1 RVB2 RVS161 RVS167 SAH1 SAP185 SAP190 SAS10 SCP160 SEC2 SEC23 SEC53 SEN15 SES1 SFB3 SGM1 SIR1 SIR3 SIT4 SNU13 SOD1 SRP1 SRV2 TEF4 THS1 TIF2, TIF1 TIF34 TIF35 TMA19 TMA29 TRP5 TSA2 TSR1 UBA1 UBI4 VMA4 VMA5 WTM1 YBL036C YBR225W YER138C YNK1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SES1 Huh WK, et al. (2003)
    [View in YRC Public Image Repository] (1 experiment(s)and 3 images)

    Protein Structure Data


    [What does the above image mean?] [View Top Sequence Alignments]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..462] PSI-BLAST 556.502279 Seryl-tRNA synthetase (SerRS)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by:     Michael Riffle