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Protein Overview: DUF1

General Information:
Name(s) found: DUF1 / YOL087C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; deletion mutant is sensitive to various chemicals including phenanthroline, sanguinarine, and nordihydroguaiaretic acid [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1116 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQLTVSYGL ISPDYCTSQD AHILPITKIL YPDIPGKNYF LTSGRDGSII LHKNTQLSNE  60
   61 PETAATTIKN DAIRMQVHSD WASDLIHVNM KNSDPSAGDT FISVSHDFSI VLISVNAQLT 120
  121 TWDKKIIGDH DDYIKCIVPI HYEMSNDYEL EEQEGGPDNV HDGINNGIVV DEQNNFLFVT 180
  181 GGLDRKIKLW CLSSGPEKMA TLLHTFDNAQ SNDTGSIYSM SPIIPKYSFD DNQTSRPFDF 240
  241 VAGDCNGDLI FYSCKYRKEV IRIQNAHRTN IKVVRTLDDS TRLISTSSDG VINVWDLNCR 300
  301 HDQTTGALQL PKKIGSWSWD SSIWCVQGTS LDKLYFGDSQ GNVMRANLSS YEDAKLTRIF 360
  361 KPDHHHHHHH HHEHEEQNIS TTDAKVKKYG GILDIALLPN EKLLFSFCTD SNLNVLDLTN 420
  421 NHFSVNEGGF ALTRSSLLTN RRHVITENTK GQMQRWDIVS CELLNTFDSS EGSFDDIVMK 480
  481 YTSKEILSHW CTVSVKVGML FVKINPKFLK TEVYGSALKD YQVVNNIEIN SDERYNLGKI 540
  541 VINSLFNEFI SYEVQKDKLL RKKIFSLKKK DLTNSLTLDT GYNSESKKNN KDKKRKSTFK 600
  601 ISSTLSIGNT NSSGTPPNSA PATPVMAETI VLEEQPLLQS ASDKAIDDSL ELVQPLPASK 660
  661 KPYFRTQSSG SLLSRKFKSF RSTSGRATTG LNTPEEPKGI LPDTPHVIND DSAFPQAINT 720
  721 TQQSKDATPE SMLWNHPFKL EQKLSAISSQ DLPSNNTHNK LRSSENSRAN STSTLEGNEK 780
  781 KKPEFMPDLL EQIQESYKQQ YMNTSSLKYL TKRLPVTKII KASSCPIIRV KSATLVLVHL 840
  841 WKEGSCGGRV LFSTLLPPSH VDNETVSGGK ENSKPPDDEE VDLQAVDDDK LGKYDLIDGE 900
  901 LGSRLNRRQI FEQLEENLPY WFAKALFRDI KTVEEQPKLN FLIMPWSSVG GSEAAGNENK 960
  961 KKFISASDTT ESSGNDSSDS SLGNGNEAVS PSTQQQFHNM LKFGRPKTSE QELNPTDLPR1020
 1021 ISEANVKLVA PGMIRVKKIK LYVADRFETK TPEMKAKMEP SLWLDLLCRG QVLDNDMTLN1080
 1081 TVRTLYWKSQ GDIVLEYRRK VHNSPLVHEV NGNEGK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) DUF1 UBP13
    View Details Krogan NJ, et al. (2006) DUF1 UBP13 UBP9
    View Details Ho Y, et al. (2002) ATP3 BEM2 COP1 DUF1 EDE1 FOL2 HTB2 LHS1 NIP1 POR1 RPG1 SES1 SRV2 TIF34 TIF35 UBI4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data DUF1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..338] PSI-BLAST 73.0 beta1-subunit of the signal-transducing G protein heterotrimer
    2 View Details [339..469] PSI-BLAST 62.69897 Tup1, C-terminal domain
    3 View Details [470..837] ab initio 11.54 No description for 1i3qA was found.
    4 View Details [838..948] ab initio 10.72 No description for 1m2vB was found.
    5 View Details [949..1116] MSA 2.004955 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle