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Protein Overview: UBP9

General Information:
Name(s) found: UBP9 / YER098W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 754 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ICLink to PubMed article]
    Biological Process: protein deubiquitination [TASLink to PubMed article]
    Molecular Function: ubiquitin-specific protease activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKRWLSVNR KKSHPEKNTQ GNDEINRKAT SLKKTKGSGD PSIAKSPSAK SSTSSIPSNL  60
   61 ASHERRSKFS SQTDNLAGNK HYHEHYHNMA STSDEREYDS STTYEDRAFD TESSILFTTI 120
  121 TDLMPYGDGS NKVFGYENFG NTCYCNSVLQ CLYNIPEFRC NVLRYPERVA AVNRIRKSDL 180
  181 KGSKIRVFTN ESFETSTNSG NSNTGYQSND NEDAHNHHHL QQSDQDNSSS STQEKQNNFE 240
  241 RKRNSFMGFG KDKSNYKDSA KKDDNNEMER PQPVHTVVMA SDTLTEKLHE GCKKIIVGRP 300
  301 LLKQSDSLSK ASTTDCQANS HCQCDSQGSR ITSVDDDVLV NPESCNDAVN NSNNNKENTF 360
  361 PTSEQRKKAA LIRGPVLNVD HLLYPTEEAT LYNGLKDIFE SITENLSLTG IVSPTEFVKI 420
  421 LKKENVLFNT MMQQDAHEFL NFLLNDFSEY IQRNNPRMRF GPQKTDNSND NFITDLFKGT 480
  481 LTNRIKCLTC DNITSRDEPF LDFPIEVQGD EETDIQKMLK SYHQREMLNG VNKFYCNKCY 540
  541 GLQEAERMVG LKQLPHILSL HLKRFKYSEE QKSNIKLFNK ILYPLTLDVS STFNTSVYKK 600
  601 YELSGVVIHM GSGPQHGHYV CICRNEKFGW LLYDDETVES IKEETVLQFT GHPGDQTTAY 660
  661 VLFYKETQAD KTENQNENID TSSQDQMQTD NNIEQLIKCD DWLRDRKLRA AANIERKKTL 720
  721 GNIPEVKTAE TKTPLNDKKR NKQKRKSRIL SFIK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) DUF1 UBP13 UBP9
    View Details Ho Y, et al. (2002) CIA1 DOG1 MDY2 MET18 RPN8 UBP9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data UBP9 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..74] deduced N/A No confident structure predictions are available.
    2 View Details [75..181] Pfam 14.823909 No description for PF00442 was found. No confident structure predictions are available.
    3 View Details [182..286] deduced N/A No confident structure predictions are available.
    4 View Details [287..530] MSA 17.244983 View MSA. No confident structure predictions are available.
    5 View Details [531..596] deduced N/A No confident structure predictions are available.
    6 View Details [597..687] Pfam 28.958607 Ubiquitin carboxyl-terminal hydrolase No confident structure predictions are available.
    7 View Details [688..754] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle