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Protein Overview: TAF5

General Information:
Name(s) found: TAF5 / YBR198C [SGD]
Description(s) found:
Found 31 descriptions.
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  • Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 798 amino acids

    Gene Ontology:
    Cellular Component: transcription factor TFIID complex [IDALink to PubMed article][TASLink to PubMed article]
    SLIK (SAGA-like) complex [IPILink to PubMed article]
    SAGA complex [IDALink to PubMed article]
    Biological Process: chromatin modification [TASLink to PubMed article]
    protein amino acid acetylation [IPILink to PubMed article]
    histone acetylation [TASLink to PubMed article]
    chromatin organization [IPILink to PubMed article]
    regulation of transcription involved in G1 phase of mitotic cell cycle [IMPLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [TASLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: general RNA polymerase II transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQKQSTNQN QNGTHQPQPV KNQRTNNAAG ANSGQQPQQQ SQGQSQQQGR SNGPFSASDL  60
   61 NRIVLEYLNK KGYHRTEAML RAESGRTLTP QNKQSPANTK TGKFPEQSSI PPNPGKTAKP 120
  121 ISNPTNLSSK RDAEGGIVSS GRLEGLNAPE NYIRAYSMLK NWVDSSLEIY KPELSYIMYP 180
  181 IFIYLFLNLV AKNPVYARRF FDRFSPDFKD FHGSEINRLF SVNSIDHIKE NEVASAFQSH 240
  241 KYRITMSKTT LNLLLYFLNE NESIGGSLII SVINQHLDPN IVESVTAREK LADGIKVLSD 300
  301 SENGNGKQNL EMNSVPVKLG PFPKDEEFVK EIETELKIKD DQEKQLNQQT AGDNYSGANN 360
  361 RTLLQEYKAM NNEKFKDNTG DDDKDKIKDK IAKDEEKKES ELKVDGEKKD SNLSSPARDI 420
  421 LPLPPKTALD LKLEIQKVKE SRDAIKLDNL QLALPSVCMY TFQNTNKDMS CLDFSDDCRI 480
  481 AAAGFQDSYI KIWSLDGSSL NNPNIALNNN DKDEDPTCKT LVGHSGTVYS TSFSPDNKYL 540
  541 LSGSEDKTVR LWSMDTHTAL VSYKGHNHPV WDVSFSPLGH YFATASHDQT ARLWSCDHIY 600
  601 PLRIFAGHLN DVDCVSFHPN GCYVFTGSSD KTCRMWDVST GDSVRLFLGH TAPVISIAVC 660
  661 PDGRWLSTGS EDGIINVWDI GTGKRLKQMR GHGKNAIYSL SYSKEGNVLI SGGADHTVRV 720
  721 WDLKKATTEP SAEPDEPFIG YLGDVTASIN QDIKEYGRRR TVIPTSDLVA SFYTKKTPVF 780
  781 KVKFSRSNLA LAGGAFRP

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ADA2 GCN5 HFI1 MOT1 NGG1 SGF11 SGF29 SGF73 SPT15 SPT20 SPT3 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF3 TAF4 TAF5 TAF6 TAF7 TAF9 TRA1 UBP8 VPS1
    View Details (MIPS) Mewes HW, et al. (2004) ADA2 GCN5 HFI1 NGG1 SGF29 SGF73 SPT20 SPT3 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF5 TAF6 TAF7 TAF9 TRA1
    View Details Krogan NJ, et al. (2006) ADA2 AHC1 AHC2 FMP40 GCN5 HFI1 MSS4 NGG1 PDR15 RAD59 REV3 SGF11 SGF29 SGF73 SNL1 SPT20 SPT3 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF3 TAF4 TAF5 TAF6 TAF7 TAF9 UBP8 YMR007W
    View Details Gavin AC, et al. (2006) TAF1 TAF11 TAF3 TAF4 TAF5
    View Details Gavin AC, et al. (2002) ADA2 ADH1 ATG26 BEM2 BUD3 CLU1 COP1 CYR1 FUN19 GCN1 GCN5 HEM13 HFI1 HRR25 IMG1 IMG2 IML1 ISW1 KAP114 KAP123 MED4 MES1 MHR1 MNN4 MOT1 MRH4 MRM1 MRP20 MRP49 MRP7 MRPL1 MRPL10 MRPL13 MRPL16 MRPL17 MRPL19 MRPL20 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL35 MRPL36 MRPL39 MRPL4 MRPL44 MRPL51 MRPL6 MRPL7 MRPL8 MYO1 MYO4 NGG1 NOP1 NUG1 PDC1 PFK2 PRP43 PSK1 PTC1 PUF6 RET2 ROM2 RPB2 RPN9 RPO21 RPT5 RTC6 RVB2 SEC1 SEC26 SEC27 SGF29 SGF73 SIN3 SIN4 SNF2 SPT15 SPT20 SPT7 SPT8 SWI3 SYP1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBF1 TEF4 UBP8 UTP20 VAS1 VPS1 YDR115W YEF3 YML6
    View Details Ho Y, et al. (2002) CCT2 CCT3 CCT5 NPA3 OLA1 SNU66 TAF5 TCP1 YER160C
    View Details Qiu et al. (2008) ADA2 AHC1 CHD1 GCN5 HFI1 MED1 MED4 MED7 NGG1 RGR1 SGF29 SGF73 SIN4 SNF2 SPT15 SPT20 SPT3 SPT7 SPT8 SRB5 SUS1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TFB5 TFG2 TRA1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TOR2 No Comments Reinke A, et al. (2004)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TAF5 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..165] MSA 2.017997 View MSA. No confident structure predictions are available.
    2 View Details [166..402] deduced N/A No confident structure predictions are available.
    3 View Details [403..798] PSI-BLAST 291.512579 Tup1, C-terminal domain
    4 View Details [723..798] PSI-BLAST 97.045757 PAF-AH Holoenzyme: Lis1/Alfa2


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle