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Bait Protein: TOR2
Organism: Saccharomyces cerevisiae
Publication: Reinke A, Anderson S, McCaffery JM, Yates J 3rd, Aronova S, Chu S, Fairclough S, Iverson C, Wedaman KP, Powers T. TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. J Biol Chem. 2004 Apr 9;279(15):14752-62. Epub 2004 Jan 21.
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  Hit Protein Protein Desc Sequence Count Spectrum Count Sequence Coverage NSAF Mol. Wt.
[View Peptides]   YDR261C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol; in YDRCTY1-3 TYB is mutant and probably no... 24 71 54.1% 0.0194 49009
[View Peptides]   YDR365W-A, YPL25... Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; ... 24 71 54.1% 0.0194 48953
[View Peptides]   YDR365W-A, YPL25... Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; ... 24 71 54.1% 0.0194 48953
[View Peptides]   RPP2B Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction ... 5 6 53.6% 0.00656 11050
[View Peptides]   RPP2A Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction... 5 11 52.8% 0.0125 10746
[View Peptides]   YDR098C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; ... 23 70 52.7% 0.0191 49057
[View Peptides]   YER159C-A, YDR31... Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; ... 23 70 52.7% 0.0191 49129
[View Peptides]   YER159C-A, YDR31... Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; ... 23 70 52.7% 0.0191 49129
[View Peptides]   RPP1A Ribosomal stalk protein P1 alpha, involved in the interaction between translational elongation facto... 3 6 39.6% 0.00681 10908
[View Peptides]   YDJ1 Protein chaperone involved in regulation of the HSP90 and HSP70 functions; involved in protein trans... 8 15 33.5% 0.00441 44671
[View Peptides]   SPT4 Protein involved in the regulating Pol I and Pol II transcription, pre-mRNA processing, kinetochore ... 4 5 33.3% 0.0059 11158
[View Peptides]   DED1 ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all ye... 11 20 32.5% 0.00398 65553
[View Peptides]   SPT5 Protein involved in regulating Pol I and Pol II transcription and pre-mRNA processing; forms a compl... 29 47 32.1% 0.00532 115650
[View Peptides]   ENO2 Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosp... 8 10 31.6% 0.00275 46914
[View Peptides]   IBI2 Protein of unknown function that associates with ribosomes; green fluorescent protein (GFP)-fusion p... 2 3 31.0% 0.00183 22179
[View Peptides]   PIN3 Protein that induces appearance of [PIN+] prion when overproduced 3 3 30.7% 0.00168 23539
[View Peptides]   DEF1 RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and prot... 17 40 30.4% 0.00652 83973
[View Peptides]   YER138C Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 38 87 28.1% 0.00596 198561
[View Peptides]   YGR038C-B Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 35 77 25.8% 0.00528 198520
[View Peptides]   YDR365W-B Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 36 85 25.6% 0.00583 198658
[View Peptides]   YDR210C-D Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 35 84 25.4% 0.00576 198838
[View Peptides]   LST8 Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; ... 7 7 25.4% 0.00278 34034
[View Peptides]   RPP0 Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphoryl... 5 9 25.3% 0.00347 33717
[View Peptides]   LSB1 Protein containing an N-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldri... 3 5 24.5% 0.0025 26139
[View Peptides]   AVO1 Component of a membrane-bound complex containing the Tor2p kinase and other proteins, which may have... 21 23 24.1% 0.00235 131378
[View Peptides]   SUP35 Translation termination factor eRF3; altered protein conformation creates the [PSI(+)] prion, a domi... 12 16 23.5% 0.00281 76551
[View Peptides]   TAF9 Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation... 2 2 22.9% 0.00153 17315
[View Peptides]   BIT61 Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p-Slm1p-Slm2p), a membrane-associated complex th... 6 7 22.7% 0.00155 60841
[View Peptides]   CMD1 Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, act... 2 4 22.4% 0.00327 16135
[View Peptides]   AVO2 Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regu... 8 9 22.3% 0.00254 47140
[View Peptides]   SAM1 S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom ... 4 4 22.3% 0.00126 41818
[View Peptides]   TOR2 PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth i... 40 67 20.5% 0.00326 281509
[View Peptides]   FKS1 Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic sub... 26 47 19.5% 0.00301 214849
[View Peptides]   SNU13 RNA binding protein, part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP invol... 2 3 19.0% 0.00286 13569
[View Peptides]   YHB1 Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role i... 3 4 18.8% 0.00121 44646
[View Peptides]   SEC17 Peripheral membrane protein required for vesicular transport between ER and Golgi, the 'priming' ste... 3 3 18.2% 0.00124 32803
[View Peptides]   NPL3 RNA-binding protein that promotes elongation, regulates termination, and carries poly(A) mRNA from n... 5 8 18.1% 0.00232 45407
[View Peptides]   LSP1 Primary component of eisosomes, which are large immobile patch structures at the cell cortex associa... 3 4 17.6% 0.00141 38071
[View Peptides]   STM1 Protein required for optimal translation under nutrient stress; perturbs association of Yef3p with r... 2 2 17.2% 8.81E-4 29995
[View Peptides]   PDC1 Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates... 4 5 16.7% 0.00107 61495
[View Peptides]   GOS1 v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GOS-28/GS28 2 2 16.6% 0.00108 25395
[View Peptides]   GSP2 GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RN... 4 6 16.4% 0.00328 24991
[View Peptides]   VMA2 Subunit B of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), a... 5 6 15.9% 0.0014 57749
[View Peptides]   SCJ1 One of several homologs of bacterial chaperone DnaJ, located in the ER lumen where it cooperates wit... 4 4 15.6% 0.00119 44800
[View Peptides]   PIL1 Primary component of eisosomes, which are large immobile cell cortex structures associated with endo... 3 3 15.0% 0.00106 38349
[View Peptides]   YHR214C-B Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 15 17 14.8% 0.00114 202816
[View Peptides]   TAF14 Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes, involved in RNA polymerase II transcrip... 2 2 14.8% 9.86E-4 27440
[View Peptides]   ERV25 Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family in... 2 3 14.2% 0.00171 24106
[View Peptides]   DIG1 Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mati... 6 6 13.9% 0.0016 49356
[View Peptides]   YLR227W-B Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 11 12 13.8% 8.23E-4 198404
[View Peptides]   SAM2 S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom ... 4 5 13.8% 0.00157 42256
[View Peptides]   YBL005W-B Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 15 24 13.7% 0.00165 198968
[View Peptides]   TIF34 eIF3i subunit of the core complex of translation initiation factor 3 (eIF3), which is essential for ... 2 2 13.5% 6.93E-4 38755
[View Peptides]   KRE2 Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation 2 2 13.1% 5.44E-4 51387
[View Peptides]   YLR227W-A, YML04... Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; ... 3 3 13.0% 8.2E-4 48993
[View Peptides]   YBL005W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; ... 4 11 12.7% 0.00301 49285
[View Peptides]   GPM1 Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycer... 2 3 12.6% 0.00146 27609
[View Peptides]   GDA1 Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golg... 5 5 12.5% 0.00116 56822
[View Peptides]   VTI1 Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and ... 2 2 12.4% 0.00111 24668
[View Peptides]   GSC2 Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore... 15 31 11.9% 0.00197 216988
[View Peptides]   PMA1 Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plas... 5 6 11.3% 7.86E-4 99619
[View Peptides]   PET123 Mitochondrial ribosomal protein of the small subunit; PET123 exhibits genetic interactions with PET1... 2 2 11.3% 7.57E-4 35998
[View Peptides]   SSP120 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytopla... 2 2 11.1% 0.00103 27289
[View Peptides]   SCS2 Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT... 2 2 11.1% 9.86E-4 26926
[View Peptides]   CDC19 Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvat... 3 3 11.0% 7.22E-4 54545
[View Peptides]   ACT1 Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functio... 2 2 10.9% 6.42E-4 41690
[View Peptides]   PSA1 GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from ... 2 2 10.5% 6.67E-4 39566
[View Peptides]   EMP70 Protein with a role in cellular adhesion and filamentous growth; similar to Tmn2p and Tmn3p; member ... 4 8 9.9% 0.00144 75963
[View Peptides]   PGK1 3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phospha... 2 3 9.6% 8.68E-4 44738
[View Peptides]   RVB1 Essential protein involved in transcription regulation; component of chromatin remodeling complexes;... 2 2 9.5% 5.2E-4 50453
[View Peptides]   TIF35 eIF3g subunit of the core complex of translation initiation factor 3 (eIF3), which is essential for ... 2 2 9.5% 8.78E-4 30501
[View Peptides]   TSC11 Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated complex that regulates... 11 12 9.3% 0.00101 164368
[View Peptides]   YHR214C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; ... 2 2 9.2% 5.03E-4 53326
[View Peptides]   PSP2 Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splic... 3 3 9.0% 6.24E-4 64020
[View Peptides]   TEF1, TEF2 Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction ... 2 3 9.0% 7.88E-4 50033
[View Peptides]   TEF1, TEF2 Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction ... 2 3 9.0% 7.88E-4 50033
[View Peptides]   NUG1 GTPase that associates with nuclear 60S pre-ribosomes, required for export of 60S ribosomal subunits... 3 5 8.8% 0.00116 57709
[View Peptides]   SHE3 Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localizat... 2 2 8.7% 5.66E-4 47417
[View Peptides]   SSZ1 Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that ... 2 2 8.6% 4.21E-4 62186
[View Peptides]   YCL019W Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 9 10 8.1% 6.8E-4 202095
[View Peptides]   YFL002W-A, YGR161W-B Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 9 10 8.1% 6.8E-4 202038
[View Peptides]   YFL002W-A, YGR161W-B Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 9 10 8.1% 6.8E-4 202038
[View Peptides]   CBF5 Pseudouridine synthase catalytic subunit of box H/ACA small nucleolar ribonucleoprotein particles (s... 2 2 8.1% 4.98E-4 54705
[View Peptides]   FBA1 Fructose 1,6-bisphosphate aldolase, required for glycolysis and gluconeogenesis; catalyzes conversio... 2 2 8.1% 6.7E-4 39621
[View Peptides]   TLG2 Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-deri... 2 2 7.8% 6.06E-4 45876
[View Peptides]   NOP56 Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that ... 2 2 7.7% 4.77E-4 56864
[View Peptides]   PBP1 Component of glucose deprivation induced stress granules, involved in P-body-dependent granule assem... 3 3 7.1% 5.0E-4 78782
[View Peptides]   MAG2 Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated pro... 3 3 6.9% 5.39E-4 76317
[View Peptides]   KAR2 ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding i... 3 3 6.9% 5.29E-4 74468
[View Peptides]   KAR2 ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding i... 3 3 6.9% 5.29E-4 74468
[View Peptides]   YML003W Putative protein of unknown function 2 2 6.9% 8.3E-4 33971
[View Peptides]   VTC4 Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) comp... 2 2 6.8% 3.71E-4 75494
[View Peptides]   TIF3 Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif ... 2 2 6.4% 5.52E-4 48522
[View Peptides]   EDE1 Key endocytic protein involved in a network of interactions with other endocytic proteins, binds mem... 4 4 6.3% 3.48E-4 150783
[View Peptides]   PFK1 Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaer... 4 5 6.3% 6.09E-4 107970
[View Peptides]   KRE6 Protein required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; appears functional... 3 4 6.1% 6.68E-4 80123
[View Peptides]   VPS1 Dynamin-like GTPase required for vacuolar sorting; also involved in actin cytoskeleton organization,... 2 2 5.8% 3.42E-4 78736
[View Peptides]   SEC9 t-SNARE protein important for fusion of secretory vesicles with the plasma membrane; similar to but ... 3 3 5.8% 5.54E-4 73624
[View Peptides]   NMD3 Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm1p-dependent adapter... 2 2 5.8% 4.65E-4 59095
[View Peptides]   MDJ1 Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p; involved in protein fol... 2 2 5.5% 4.71E-4 55561
[View Peptides]   VMA6 Subunit d of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase), an elect... 2 2 5.5% 6.97E-4 39791
[View Peptides]   CHS3 Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for ... 2 2 5.4% 2.07E-4 131601
[View Peptides]   TAF5 Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation... 2 2 5.4% 3.02E-4 88968
[View Peptides]   OSM1 Fumarate reductase, catalyzes the reduction of fumarate to succinate, required for the reoxidation o... 2 2 5.4% 4.8E-4 55065
[View Peptides]   TRZ1 tRNA 3'-end processing endonuclease tRNase Z; also localized to mitochondria and interacts genetical... 2 2 4.8% 2.87E-4 96816
[View Peptides]   SMY2 Protein of unknown function involved in COPII vesicle formation; interacts with the Sec23p/Sec24p su... 2 2 4.6% 3.05E-4 87098
[View Peptides]   MOT3 Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of ... 2 2 4.5% 4.91E-4 54382
[View Peptides]   SSD1 Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathw... 2 2 4.1% 1.92E-4 139954
[View Peptides]   HXT7 High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, e... 2 2 4.0% 4.22E-4 62735
[View Peptides]   HXT6 High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, e... 2 2 4.0% 4.22E-4 62705
[View Peptides]   VTC3 Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuol... 2 2 3.7% 2.88E-4 96553
[View Peptides]   YJL206C Putative protein of unknown function; similar to transcriptional regulators from the Zn[2]-Cys[6] bi... 2 2 3.7% 3.17E-4 86663
[View Peptides]   NAM7 ATP-dependent RNA helicase of the SFI superfamily involved in nonsense mediated mRNA decay; required... 2 2 3.5% 2.48E-4 109430
[View Peptides]   TOR1 PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in... 5 8 3.2% 3.9E-4 281138
[View Peptides]   CHS1 Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-ac... 2 2 2.6% 2.13E-4 129919
[View Peptides]   YFR016C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... 2 2 2.4% 1.95E-4 137698
[View Peptides]   FAS1 Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty a... 2 2 2.0% 1.17E-4 228689
[View Peptides]   KIC1 Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possibly through regulati... 2 2 0.8% 2.23E-4 117061

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