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Protein Overview: TAF14

General Information:
Name(s) found: TAF14 / YPL129W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes, involved in RNA polymerase II transcription initiation and in chromatin modification; contains a YEATS domain [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 244 amino acids

    Gene Ontology:
    Cellular Component: SWI/SNF complex [IPILink to PubMed article]
    transcription factor TFIID complex [IDALink to PubMed article][TASLink to PubMed article]
    Ino80 complex [IPILink to PubMed article]
    transcription factor TFIIF complex [IPILink to PubMed article][TASLink to PubMed article]
    histone acetyltransferase complex [IPILink to PubMed article]
    Biological Process: chromatin remodeling [TASLink to PubMed article]
    regulation of transcription involved in G1 phase of mitotic cell cycle [IPILink to PubMed articleLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [TASLink to PubMed articleLink to PubMed article]
    Molecular Function: general RNA polymerase II transcription factor activity [TASLink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVATVKRTIR IKTQQHILPE VPPVENFPVR QWSIEIVLLD DEGKEIPATI FDKVIYHLHP  60
   61 TFANPNRTFT DPPFRIEEQG WGGFPLDISV FLLEKAGERK IPHDLNFLQE SYEVEHVIQI 120
  121 PLNKPLLTEE LAKSGSTEET TANTGTIGKR RTTTNTTAEP KAKRAKTGSA STVKGSVDLE 180
  181 KLAFGLTKLN EDDLVGVVQM VTDNKTPEMN VTNNVEEGEF IIDLYSLPEG LLKSLWDYVK 240
  241 KNTE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARP4 ARP8 DST1 IES1 IES3 IES5 INO80 IWR1 NHP10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPO21 RPO26 SWI3 TAF14 TAF8 TFG1 TFG2
    View Details (MIPS) Mewes HW, et al. (2004) ARP7 ARP9 CSE2 DMC1 GAL11 MED11 MED2 MED4 MED6 MED7 MED8 NUT1 NUT2 PGD1 RGR1 ROX3 SIN4 SNF11 SNF12 SNF2 SNF5 SNF6 SRB2 SRB4 SRB5 SRB6 SRB7 SWI1 SWI3 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF5 TAF6 TAF7 TAF9 TFG1 TFG2
    View Details Krogan NJ, et al. (2006) ALG3 BUD27 CBF2 DST1 ESS1 IWR1 RPB10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPO21 RPO26 SPT4 TAF14 TFG1 TFG2 YBL059W YBR259W YPL225W
    View Details Gavin AC, et al. (2002) ABD1 ADA2 ADH1 AOS1 CLU1 FUN19 GCN5 HEM13 IWR1 KAP114 KAP123 MED4 MES1 MNN4 MOT1 MYO1 NGG1 NOP1 PFK2 PSK1 PTC1 PUF6 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPN9 RPO21 RPO26 RPT5 RVB2 SGF29 SGF73 SIN3 SIN4 SPT15 SPT20 SPT4 SPT5 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBF1 TEF4 TFG1 TFG2 VAS1 VPS1
    View Details Ho Y, et al. (2002) ADH2 ARP4 ATE1 CDC16 CDC33 CDC5 CKA2 EAF1 EPL1 ERB1 ESA1 FPR3 HHF1, HHF2 HHO1 HRR25 ICP55 KRE33 KRI1 LOC1 MES1 MGM101 MKT1 MMS4 MUS81 NHP2 NOP12 NOP2 NUG1 POR1 PWP1 RAD53 RPC10 RPF2 SAP185 SEC23 SIT4 TAF14 TAF4 TIP41 TMA29 TRA1 TUF1 UBI4 UTP22 YHB1 YRA1
    View Details Qiu et al. (2008) ADA2 ARP4 ARP5 ARP7 ARP9 BDF1 CHD1 CSE2 GAL11 GCN5 HFI1 IES3 MED1 MED11 MED2 MED4 MED6 MED7 MED8 NGG1 NUT1 NUT2 PGD1 RGR1 ROX3 RPB11 RPB2 RPB3 RPB4 RPB7 RPB8 RSC2 RSC8 RTT102 SFH1 SGF11 SGF29 SGF73 SIN4 SNF11 SNF12 SNF2 SNF5 SNF6 SOH1 SPT15 SPT20 SPT3 SPT7 SPT8 SRB2 SRB4 SRB5 SRB6 SRB7 SSL1 STH1 SUS1 SWI1 SWI3 SWP82 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TFA1 TFA2 TFB5 TFC8 TFG1 TFG2 TRA1 UBP8

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TOR2 No Comments Reinke A, et al. (2004)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data TAF14 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..154] Pfam 57.60206 YEATS family No confident structure predictions are available.
    2 View Details [155..244] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle