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Protein Overview: ARP4

General Information:
Name(s) found: ARP4 / YJL081C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 489 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [IDALink to PubMed article]
    NuA4 histone acetyltransferase complex [IPILink to PubMed article]
    Swr1 complex [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    Ino80 complex [IPILink to PubMed article]
    Biological Process: DNA repair [IDALink to PubMed articleLink to PubMed article][IMPLink to PubMed article]
    chromatin remodeling [IDALink to PubMed article]
    regulation of transcription, DNA-dependent [IMPLink to PubMed article]
    histone acetylation [IDALink to PubMed article]
    chromatin organization [IMPLink to PubMed article][IPILink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [IDALink to PubMed article]
    Molecular Function: histone acetyltransferase activity [IMPLink to PubMed article]
    ATP-dependent 5'-3' DNA helicase activity [IDALink to PubMed article]
    chromatin binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNAALQVYG GDEVSAVVID PGSYTTNIGY SGSDFPQSIL PSVYGKYTAD EGNKKIFSEQ  60
   61 SIGIPRKDYE LKPIIENGLV IDWDTAQEQW QWALQNELYL NSNSGIPALL TEPVWNSTEN 120
  121 RKKSLEVLLE GMQFEACYLA PTSTCVSFAA GRPNCLVVDI GHDTCSVSPI VDGMTLSKST 180
  181 RRNFIAGKFI NHLIKKALEP KEIIPLFAIK QRKPEFIKKT FDYEVDKSLY DYANNRGFFQ 240
  241 ECKETLCHIC PTKTLEETKT ELSSTAKRSI ESPWNEEIVF DNETRYGFAE ELFLPKEDDI 300
  301 PANWPRSNSG VVKTWRNDYV PLKRTKPSGV NKSDKKVTPT EEKEQEAVSK STSPAANSAD 360
  361 TPNETGKRPL EEEKPPKENN ELIGLADLVY SSIMSSDVDL RATLAHNVVL TGGTSSIPGL 420
  421 SDRLMTELNK ILPSLKFRIL TTGHTIERQY QSWLGGSILT SLGTFHQLWV GKKEYEEVGV 480
  481 ERLLNDRFR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARP4 ARP5 ARP6 ARP8 BDF1 EAF1 EAF3 EAF5 EAF6 EAF7 EPL1 ESA1 IES1 IES2 IES3 IES5 INO80 NHP10 RVB1 RVB2 SWC3 SWC4 SWC5 SWC7 SWR1 TAF14 TRA1 VPS71 VPS72 YAF9 YNG2
    View Details Hazbun TR, et al. (2003) ARP4 EAF1 EAF5 EPL1 ESA1 RVB1 RVB2 SWC4 SWR1 TRA1 YAF9 YNG2
    View Details Krogan NJ, et al. (2006) ARP4 ARP5 ARP6 ARP8 CCA1 EAF1 EAF5 EAF6 EAF7 EPL1 ESA1 IES1 IES2 IES3 IES4 IES5 IES6 INO80 NHP10 NTO1 PIH1 RVB1 RVB2 SAS3 SWC3 SWC4 SWC5 SWC7 SWR1 TAH1 TRA1 VPS71 VPS72 YAF9 YNG2
    View Details Gavin AC, et al. (2002) ACT1 ADH1 ARP4 ARP8 EAF1 EAF3 EAF5 EPL1 ESA1 ESC8 HHF1, HHF2 IES1 IES5 INO80 IOC3 ISW1 ISW2 ITC1 MOT1 NHP10 NPL6 RPC40 RSC2 RSC4 RSC58 RSC6 RSC8 RVB2 SIN3 TRA1 VPS1 YAF9 YAP1
    View Details Ho Y, et al. (2002) AAC3 ARP4 ASA1 ATE1 ATG17 ATG29 ATP3 CDC33 CIC1 CIS1 CKA2 CYS4 EAF1 EPL1 ESA1 FAA2 FOL2 GRH1 HAP2 HAP5 HFI1 HRR25 IPP1 LOC1 MAM33 MTQ1 NAP1 NMD5 NOP16 NSA2 POL5 POR1 PSE1 RHR2 RPO31 SAH1 SAP185 SAP190 SIT4 SPE3 SPT7 SSK2 STB4 SWC4 SWI5 TAF14 TAF4 TIF1, TIF2 TIF6 TIP41 TRA1 TUF1 YRA1 YRA2 YTM1
    View Details Qiu et al. (2008) ABF1 ACT1 ADA2 AHC1 ARP4 ARP5 ARP6 CHD1 EAF3 EAF7 EPL1 ESA1 FPR4 GCN5 HFI1 HHF1, HHF2 INO80 KAE1 PCC1 POB3 RVB1 RVB2 SAS2 SAS3 SAS4 SAS5 SGF29 SGF73 SPT20 SPT7 SUB2 SUS1 SWC4 TAF10 TAF14 TBF1 TRA1 VPS71 YNG1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run SWC4 No Comments Hazbun TR, et al. (2003)
    View Run SWC4 No Comments Hazbun TR, et al. (2003)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ARP4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..142]
    [452..489]    		 PSI-BLAST 1220.0 No description for 1dgaA_ was found.
    2 View Details [143..451] PSI-BLAST 1220.0 No description for 1dgaA_ was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle