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Protein Overview: TAF10

General Information:
Name(s) found: TAF10 / YDR167W [SGD]
Description(s) found:
Found 32 descriptions.
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  • Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 206 amino acids

    Gene Ontology:
    Cellular Component: transcription factor TFIID complex [IDALink to PubMed article][TASLink to PubMed article]
    SLIK (SAGA-like) complex [IPILink to PubMed article]
    SAGA complex [IDALink to PubMed article]
    Biological Process: chromatin modification [TASLink to PubMed article]
    protein amino acid acetylation [IPILink to PubMed article]
    histone acetylation [TASLink to PubMed article]
    chromatin organization [IPILink to PubMed article]
    regulation of transcription involved in G1 phase of mitotic cell cycle [IPILink to PubMed articleLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [TASLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: general RNA polymerase II transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFEEDYDAE FDDNQEGQLE TPFPSVAGAD DGDNDNDDSV AENMKKKQKR EAVVDDGSEN  60
   61 AFGIPEFTRK DKTLEEILEM MDSTPPIIPD AVIDYYLTKN GFNVADVRVK RLLALATQKF 120
  121 VSDIAKDAYE YSRIRSSVAV SNANNSQARA RQLLQGQQQP GVQQISQQQH QQNEKTTASK 180
  181 VVLTVNDLSS AVAEYGLNIG RPDFYR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ADA2 GCN5 HFI1 NGG1 SGF11 SGF29 SGF73 SPT20 SPT3 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF3 TAF4 TAF5 TAF6 TAF7 TAF9 UBP8
    View Details (MIPS) Mewes HW, et al. (2004) ADA2 GCN5 HFI1 NGG1 SGF29 SGF73 SPT20 SPT3 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF5 TAF6 TAF7 TAF9 TRA1
    View Details Krogan NJ, et al. (2006) ADA2 AHC1 AHC2 FMP40 GCN5 HFI1 MSS4 NGG1 PDR15 RAD59 REV3 SGF11 SGF29 SGF73 SNL1 SPT20 SPT3 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF3 TAF4 TAF5 TAF6 TAF7 TAF9 UBP8 YMR007W
    View Details Gavin AC, et al. (2002) ADA2 ADH1 CLU1 FUN19 GCN5 HEM13 HFI1 KAP114 KAP123 MED4 MES1 MNN4 MOT1 MYO1 MYO4 NGG1 NOP1 PFK2 PSK1 PTC1 PUF6 RPB2 RPN9 RPO21 RPT5 RVB2 SGF29 SGF73 SIN3 SIN4 SPT15 SPT20 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBF1 TEF4 UBP8 VAS1 VPS1
    View Details Qiu et al. (2008) ADA2 ARP4 EPL1 GAL11 GCN5 HFI1 MED1 MED11 MED2 MED6 MED7 NGG1 NUT1 NUT2 PGD1 RGR1 ROX3 RPB4 SGF11 SGF29 SGF73 SIN4 SPT15 SPT20 SPT3 SPT7 SPT8 SRB4 SRB5 SRB6 SRB7 SSL2 SUS1 SWC4 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TFA1 TFB5 TFG1 TFG2 TRA1 UBP8

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TAF10 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..66] deduced N/A No confident structure predictions are available.
    2 View Details [67..206] Pfam 36.619789 Transcription initiation factor TFIID 23-30kDa subunit No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  8.88482968293417 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  5.93249134612505 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  5.93249134612505 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  4.49084162254966 bayes_pls_golite062009
  • DNA binding
    		•  4.24660531286828 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  4.2172829451557 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.14026521609645 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.91807454227165 bayes_pls_golite062009
  • acetyltransferase activity
    		•  3.91533222675137 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  3.78067108255869 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.38996237245502 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.35419529667223 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.18312128320637 bayes_pls_golite062009
  • binding
    		•  3.14832737946099 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.02428691626433 bayes_pls_golite062009
  • transcription factor activity
    		•  2.39322722597434 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.83714729861923 bayes_pls_golite062009
  • transcription activator activity
    		•  1.12739348005764 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.03060091158028 bayes_pls_golite062009
  • protein binding
    		•  1.01897642648285 bayes_pls_golite062009
  • transcription factor binding
    		•  1.01773884290535 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.976797801726735 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.840442755533537 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.621482805601238 bayes_pls_golite062009
  • histone binding
    		•  0.184823910505751 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0585868733603467 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle