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Protein Overview: MNN4

General Information:
Name(s) found: MNN4 / YKL201C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1178 amino acids

    Gene Ontology:
    Cellular Component: membrane [ISSLink to PubMed article]
    Biological Process: protein amino acid O-linked glycosylation [IMPLink to PubMed article]
    protein amino acid N-linked glycosylation [IMPLink to PubMed article]
    response to stress [IDALink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQRISSKLH RRFLSGLLRV KHYPLRRILL PLILLQIIII TFIWSNSPQR NGLGRDADYL  60
   61 LPNYNELDSD DDSWYSILTS SFKNDRKIQF AKTLYENLKF GTNPKWVNEY TLQNDLLSVK 120
  121 MGPRKGSKLE SVDELKFYDF DPRLTWSVVL NHLQNNDADQ PEKLPFSWYD WTTFHELNKL 180
  181 ISIDKTVLPC NFLFQSAFDK ESLEAIETEL GEPLFLYERP KYAQKLWYKA ARNQDRIKDS 240
  241 KELKKHCSKL FTPDGHGSPK GLRFNTQFQI KELYDKVRPE VYQLQARNYI LTTQSHPLSI 300
  301 SIIESDNSTY QVPLQTEKSK NLVQSGLLQE YINDNINSTN KRKKNKQDVE FNHNRLFQEF 360
  361 VNNDQVNSLY KLEIEETDKF TFDKDLVYLS PSDFKFDASK KIEELEEQKK LYPDKFSAHN 420
  421 ENYLNSLKNS VKTSPALQRK FFYEAGAVKQ YKGMGFHRDK RFFNVDTLIN DKQEYQARLN 480
  481 SMIRTFQKFT KANGIISWLS HGTLYGYLYN GMAFPWDNDF DLQMPIKHLQ LLSQYFNQSL 540
  541 ILEDPRQGNG RYFLDVSDSL TVRINGNGKN NIDARFIDVD TGLYIDITGL ASTSAPSRDY 600
  601 LNSYIEERLQ EEHLDINNIP ESNGETATLP DKVDDGLVNM ATLNITELRD YITSDENKNH 660
  661 KRVPTDTDLK DLLKKELEEL PKSKTIENKL NPKQRYFLNE KLKLYNCRNN HFNSFEELSP 720
  721 LINTVFHGVP ALIPHRHTYC LHNEYHVPDR YAFDAYKNTA YLPEFRFWFD YDGLKKCSNI 780
  781 NSWYPNIPSI NSWNPNLLKE ISSTKFESKL FDSNKVSEYS FKNLSMDDVR LIYKNIPKAG 840
  841 FIEVFTNLYN SFNVTAYRQK ELEIQYCQNL TFIEKKKLLH QLRINVAPKL SSPAKDPFLF 900
  901 GYEKAMWKDL SKSMNQTTLD QVTKIVHEEY VGKIIDLSES LKYRNFSLFN ITFDETGTTL 960
  961 DDNTEDYTPA NTVEVNPVDF KSNLNFSSNS FLDLNSYGLD LFAPTLSDVN RKGIQMFDKD1020
 1021 PIIVYEDYAY AKLLEERKRR EKKKKEEEEK KKKEEEEKKK KEEEEKKKKE EEEKKKKEEE1080
 1081 EKKKKEEEEK KKQEEEEKKK KEEEEKKKQE EGEKMKNEDE ENKKNEDEEK KKNEEEEKKK1140
 1141 QEEKNKKNED EEKKKQEEEE KKKNEEEEKK KQEEGHSN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2002) ADA2 ADH1 CLU1 FUN19 GCN5 HEM13 KAP114 KAP123 MED4 MES1 MNN4 MOT1 MYO1 NGG1 NOP1 PFK2 PSK1 PTC1 PUF6 RPB2 RPN9 RPO21 RPT5 RVB2 SGF29 SGF73 SIN3 SIN4 SPT15 SPT20 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBF1 TEF4 VAS1 VPS1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
    View Run BOI1 Sample bob1 (2nd set) from october 2005 McCusker D, et al (2007)
    View Run MLP2 #33 Asynchronous SPB prep Keck JM, et al. (2011)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..164] MSA 1.026969 View MSA. No confident structure predictions are available.
    2 View Details [165..257] deduced N/A No confident structure predictions are available.
    3 View Details [258..689] MSA 7.161997 View MSA. No confident structure predictions are available.
    4 View Details [690..1122] PSI-BLAST 16.39794 Heavy meromyosin subfragment
    5 View Details [1123..1178] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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