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Protein Overview: RPO26

General Information:
Name(s) found: RPO26 / YPR187W [SGD]
Description(s) found:
Found 115 descriptions.
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  • RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 155 amino acids

    Gene Ontology:
    Cellular Component: DNA-directed RNA polymerase I complex [TASLink to PubMed article]
    DNA-directed RNA polymerase III complex [TASLink to PubMed article]
    DNA-directed RNA polymerase II, core complex [TASLink to PubMed article]
    Biological Process: transcription from RNA polymerase III promoter [TAS]
    transcription from RNA polymerase I promoter [TAS]
    transcription from RNA polymerase II promoter [TASLink to PubMed article]
    Molecular Function: DNA-directed RNA polymerase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDYEEAFND GNENFEDFDV EHFSDEETYE EKPQFKDGET TDANGKTIVT GGNGPEDFQQ  60
   61 HEQIRRKTLK EKAIPKDQRA TTPYMTKYER ARILGTRALQ ISMNAPVFVD LEGETDPLRI 120
  121 AMKELAEKKI PLVIRRYLPD GSFEDWSVEE LIVDL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) DST1 IWR1 RET1 RPA12 RPA135 RPA14 RPA190 RPA34 RPA43 RPA49 RPB10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPC10 RPC11 RPC17 RPC19 RPC25 RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO21 RPO26 RPO31 SPT4 SPT5 TAF14 TFG1 TFG2
    View Details (MIPS) Mewes HW, et al. (2004) CDC73 RET1 RPA12 RPA135 RPA14 RPA190 RPA34 RPA43 RPA49 RPB10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPC10 RPC19 RPC25 RPC31 RPC34 RPC40 RPC82 RPO21 RPO26 RPO31
    View Details Krogan NJ, et al. (2006) ALG3 BUD27 CBF2 DST1 ESS1 IWR1 RPB10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPO21 RPO26 SPT4 TAF14 TFG1 TFG2 YBL059W YBR259W YPL225W
    View Details Gavin AC, et al. (2002) ABD1 AMS1 AOS1 ASC1 CDC14 DHH1 FBA1 IWR1 MAF1 RET1 RPA12 RPA135 RPA190 RPA43 RPA49 RPB10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPC11 RPC17 RPC19 RPC25 RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO21 RPO26 RPO31 RSC8 SPT4 SPT5 SRO7 TAF14 TFG1 TFG2
    View Details Ho Y, et al. (2002) ACC1 ACH1 ADH2 ADR1 ART10 BUL1 GCD11 GFA1 GND1 GUS1 HXT6 IDH2 ISA2 LSB1 MDH1 MET18 NGL2 PHO84 PYC1 PYC2 RET1 RNQ1 RPA135 RPA190 RPA49 RPB3 RPB5 RPC19 RPC25 RPC34 RPC40 RPC82 RPN3 RPO21 RPO26 RPO31 RSP5 RVS167 SEC27 TBS1 TFP1 TSA2 YFL042C YHR112C YKR018C
    View Details Qiu et al. (2008) RET1 RPA12 RPA135 RPA14 RPA190 RPA34 RPA43 RPA49 RPB10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPC10 RPC11 RPC17 RPC19 RPC25 RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO21 RPO26 RPO31 TFG1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen NUP1 RPO26 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RPO26 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..155] PSI-BLAST 815.68867 RPB6

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA-directed RNA polymerase activity
    		•  8.95763217796707 bayes_pls_golite062009
  • RNA polymerase activity
    		•  8.95763217796707 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  6.40098308297479 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.33401073482737 bayes_pls_golite062009
  • transferase activity
    		•  3.84777794959854 bayes_pls_golite062009
  • binding
    		•  2.4602171483686 bayes_pls_golite062009
  • DNA binding
    		•  1.9558633290744 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.91068858292286 bayes_pls_golite062009
  • catalytic activity
    		•  0.902495165806215 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle