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Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases. Catalyzed by a DNA-directed RNA polymerase that forms a complex with alpha DNA polymerase. Catalysis of the transfer of a nucleotidyl group to a reactant.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: DNA-directed RNA polymerase activity
Acc: GO:0003899
Aspect: Molecular Function
Desc: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
Synonyms:
  • DNA-directed RNA polymerase III activity
  • deoxyribonucleic acid-dependent ribonucleic acid polymerase activity
  • RNA nucleotidyltransferase (DNA-directed) activity
  • RNA polymerase I activity
  • DNA-directed RNA polymerase II activity
  • GO:0000129
  • DNA-dependent RNA nucleotidyltransferase activity
  • transcriptase
  • C RNA formation factors
  • DNA-dependent RNA polymerase activity
  • C ribonucleic acid formation factors
  • DNA-dependent ribonucleate nucleotidyltransferase activity
  • RNA polymerase II activity
  • DNA-directed RNA polymerase I activity
  • nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) activity
  • RNA polymerase III activity
Proteins in PDR annotated with:
   This term: 350 [Search]
   Term or descendants: 391 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003899 - DNA-directed RNA polymerase activity (interactive image map)

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