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Protein Overview: SNF5

General Information:
Name(s) found: SNF5 / YBR289W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf6p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 905 amino acids

    Gene Ontology:
    Cellular Component: SWI/SNF complex [TASLink to PubMed article]
    chromatin remodeling complex [TASLink to PubMed article]
    Biological Process: chromatin remodeling [TASLink to PubMed article]
    double-strand break repair [IMPLink to PubMed article]
    Molecular Function: general RNA polymerase II transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNQPQGTNS VPNSIGNIFS NIGTPSFNMA QIPQQLYQSL TPQQLQMIQQ RHQQLLRSRL  60
   61 QQQQQQQQQT SPPPQTHQSP PPPPQQSQPI ANQSATSTPP PPPAPHNLHP QIGQVPLAPA 120
  121 PINLPPQIAQ LPLATQQQVL NKLRQQAIAK NNPQVVNAIT VAQQQVQRQI EQQKGQQTAQ 180
  181 TQLEQQRQLL VQQQQQQQLR NQIQRQQQQQ FRHHVQIQQQ QQKQQQQQQQ HQQQQQQQQQ 240
  241 QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQGQ IPQSQQVPQV RSMSGQPPTN VQPTIGQLPQ 300
  301 LPKLNLPKYQ TIQYDPPETK LPYPTYWSDK KADTDTLLYE QIIQRDKINK YSLIRETNGY 360
  361 DPFSIYGFSN KEYISRLWHT LKYYQDLKNT RMKSITSTSQ KIPSASIWGN GYSGYGNGIT 420
  421 NTTTRVIPQV EVGNRKHYLE DKLKVYKQAM NETSEQLVPI RLEFDQDRDR FFLRDTLLWN 480
  481 KNDKLIKIED FVDDMLRDYR FEDATREQHI DTICQSIQEQ IQEFQGNPYI ELNQDRLGGD 540
  541 DLRIRIKLDI VVGQNQLIDQ FEWEISNSDN CPEEFAESMC QELELPGEFV TAIAHSIREQ 600
  601 VHMYHKSLAL LGYNFDGSAI EDDDIRSRML PTITLDDVYR PAAESKIFTP NLLQISAAEL 660
  661 ERLDKDKDRD TRRKRRQGRS NRRGMLALSG TSASNTSMNG VHNTVAAGNA SSLPPGEILL 720
  721 PDIADIPRTF RTPVPSTLMP GGVDVGPSVE SYELRNTTTY KSRPDRPKPV SPPCYIIDHI 780
  781 PGHSLLLSIK LPGKVNTKEE FAAAPNDTSS GTNAMLPSPE SLKTKLNSNI RAGVTIPSIP 840
  841 NPIANHTVTN SPNPTLQPVI PGGAASKSVP TPSLPIAPPV APHDSEATLL TNSNNGSSNN 900
  901 NTQNT

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARP7 ARP9 SNF11 SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 SWP82
    View Details (MIPS) Mewes HW, et al. (2004) ARP7 ARP9 SNF11 SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 TAF14
    View Details Krogan NJ, et al. (2006) SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 SWP82
    View Details Gavin AC, et al. (2006) ARP9 SNF11 SNF12 SNF5 SNF6 SWI1 SWI3
    View Details Gavin AC, et al. (2002) ADH1 ARP9 BEM2 CBF5 DIM1 ECM16 EMG1 ENP1 HRR25 IMP3 IMP4 KRE33 KRR1 LTV1 MPP10 NOB1 NOC4 NOP1 NOP14 PNO1 RCL1 RIO2 RRP12 SAM1 SLX9 SNF12 SNF2 SNF5 SNF6 SOF1 SWI1 SWI3 SWP82 TSR1 UTP15 UTP20 UTP22 UTP6 UTP7 VPS1 YGR054W
    View Details Qiu et al. (2008) ARP7 ARP9 SNF11 SNF12 SNF2 SNF5 SNF6 STH1 SWI1 SWI3 SWP82 TAF14 TFB5

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SNF5 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..123] ORFEUS 9.11 RBP1
    2 View Details [124..538] ORFEUS 9.7 Sec24
    3 View Details [539..905] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle