| General Information: |
|
| Name(s) found: |
FAS1 /
YKL182W
[SGD]
|
| Description(s) found:
Found 28 descriptions. SHOW ALL |
|
| Organism: | Saccharomyces cerevisiae |
| Length: | 2051 amino acids |
Gene Ontology: |
|
| Cellular Component: |
fatty acid synthase complex
[IDA ]
mitochondrion [IDA ]
cytosol [TAS] |
| Biological Process: |
fatty acid biosynthetic process
[TAS]
|
| Molecular Function: |
[acyl-carrier-protein] S-malonyltransferase activity
[IMP]
3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity [IMP ]
enoyl-[acyl-carrier-protein] reductase (NADH) activity [IMP ]
[acyl-carrier-protein] S-acetyltransferase activity [IMP ]
|
| Sequence: |
|
| Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51
| | | | | |
1 MDAYSTRPLT LSHGSLEHVL LVPTASFFIA SQLQEQFNKI LPEPTEGFAA DDEPTTPAEL 60
61 VGKFLGYVSS LVEPSKVGQF DQVLNLCLTE FENCYLEGND IHALAAKLLQ ENDTTLVKTK 120
121 ELIKNYITAR IMAKRPFDKK SNSALFRAVG EGNAQLVAIF GGQGNTDDYF EELRDLYQTY 180
181 HVLVGDLIKF SAETLSELIR TTLDAEKVFT QGLNILEWLE NPSNTPDKDY LLSIPISCPL 240
241 IGVIQLAHYV VTAKLLGFTP GELRSYLKGA TGHSQGLVTA VAIAETDSWE SFFVSVRKAI 300
301 TVLFFIGVRC YEAYPNTSLP PSILEDSLEN NEGVPSPMLS ISNLTQEQVQ DYVNKTNSHL 360
361 PAGKQVEISL VNGAKNLVVS GPPQSLYGLN LTLRKAKAPS GLDQSRIPFS ERKLKFSNRF 420
421 LPVASPFHSH LLVPASDLIN KDLVKNNVSF NAKDIQIPVY DTFDGSDLRV LSGSISERIV 480
481 DCIIRLPVKW ETTTQFKATH ILDFGPGGAS GLGVLTHRNK DGTGVRVIVA GTLDINPDDD 540
541 YGFKQEIFDV TSNGLKKNPN WLEEYHPKLI KNKSGKIFVE TKFSKLIGRP PLLVPGMTPC 600
601 TVSPDFVAAT TNAGYTIELA GGGYFSAAGM TAAIDSVVSQ IEKGSTFGIN LIYVNPFMLQ 660
661 WGIPLIKELR SKGYPIQFLT IGAGVPSLEV ASEYIETLGL KYLGLKPGSI DAISQVINIA 720
721 KAHPNFPIAL QWTGGRGGGH HSFEDAHTPM LQMYSKIRRH PNIMLIFGSG FGSADDTYPY 780
781 LTGEWSTKFD YPPMPFDGFL FGSRVMIAKE VKTSPDAKKC IAACTGVPDD KWEQTYKKPT 840
841 GGIVTVRSEM GEPIHKIATR GVMLWKEFDE TIFNLPKNKL VPTLEAKRDY IISRLNADFQ 900
901 KPWFATVNGQ ARDLATMTYE EVAKRLVELM FIRSTNSWFD VTWRTFTGDF LRRVEERFTK 960
961 SKTLSLIQSY SLLDKPDEAI EKVFNAYPAA REQFLNAQDI DHFLSMCQNP MQKPVPFVPV1020
1021 LDRRFEIFFK KDSLWQSEHL EAVVDQDVQR TCILHGPVAA QFTKVIDEPI KSIMDGIHDG1080
1081 HIKKLLHQYY GDDESKIPAV EYFGGESPVD VQSQVDSSSV SEDSAVFKAT SSTDEESWFK1140
1141 ALAGSEINWR HASFLCSFIT QDKMFVSNPI RKVFKPSQGM VVEISNGNTS SKTVVTLSEP1200
1201 VQGELKPTVI LKLLKENIIQ MEMIENRTMD GKPVSLPLLY NFNPDNGFAP ISEVMEDRNQ1260
1261 RIKEMYWKLW IDEPFNLDFD PRDVIKGKDF EITAKEVYDF THAVGNNCED FVSRPDRTML1320
1321 APMDFAIVVG WRAIIKAIFP NTVDGDLLKL VHLSNGYKMI PGAKPLQVGD VVSTTAVIES1380
1381 VVNQPTGKIV DVVGTLSRNG KPVMEVTSSF FYRGNYTDFE NTFQKTVEPV YQMHIKTSKD1440
1441 IAVLRSKEWF QLDDEDFDLL NKTLTFETET EVTFKNANIF SSVKCFGPIK VELPTKETVE1500
1501 IGIVDYEAGA SHGNPVVDFL KRNGSTLEQK VNLENPIPIA VLDSYTPSTN EPYARVSGDL1560
1561 NPIHVSRHFA SYANLPGTIT HGMFSSASVR ALIENWAADS VSSRVRGYTC QFVDMVLPNT1620
1621 ALKTSIQHVG MINGRKLIKF ETRNEDDVVV LTGEAEIEQP VTTFVFTGQG SQEQGMGMDL1680
1681 YKTSKAAQDV WNRADNHFKD TYGFSILDIV INNPVNLTIH FGGEKGKRIR ENYSAMIFET1740
1741 IVDGKLKTEK IFKEINEHST SYTFRSEKGL LSATQFTQPA LTLMEKAAFE DLKSKGLIPA1800
1801 DATFAGHSLG EYAALASLAD VMSIESLVEV VFYRGMTMQV AVPRDELGRS NYGMIAINPG1860
1861 RVAASFSQEA LQYVVERVGK RTGWLVEIVN YNVENQQYVA AGDLRALDTV TNVLNFIKLQ1920
1921 KIDIIELQKS LSLEEVEGHL FEIIDEASKK SAVKPRPLKL ERGFACIPLV GISVPFHSTY1980
1981 LMNGVKPFKS FLKKNIIKEN VKVARLAGKY IPNLTAKPFQ VTKEYFQDVY DLTGSEPIKE2040
2041 IIDNWEKYEQ S |
| PUBLICATION | TOPOLOGY | COCOMPLEXED PROTEINS | |
| View Details | Riffle et al. (2010) (Unpublished Data) |
|
ADH3 FAS1 FIT1 HXK1 |
| View Details | (MIPS) Mewes HW, et al. (2004) |
|
FAS1 FAS2 |
| View Details | Krogan NJ, et al. (2006) |
|
FAS1 FAS2 SLM2 |
| View Details | Gavin AC, et al. (2006) |
|
FAS1 TRM3 |
The following runs contain data for this protein:
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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| PROTEIN(S) | PUBLICATION | |
| View Data |
|
Huh WK, et al. (2003) |
Domains predicted:
| # | Region(s) | Method | Confidence | Match Description | |
| 1 | View Details | [1..138] |  |
N/A | No confident structure predictions are available. |
| 2 | View Details | [139..552] | |
22.063983 | View MSA. No confident structure predictions are available. |
| 3 | View Details | [553..645] | |
N/A | No confident structure predictions are available. |
| 4 | View Details | [646..839] | |
4.522879 | Inosine monophosphate dehydrogenase (IMPDH) |
| 5 | View Details | [840..1276] | |
N/A | No confident structure predictions are available. |
| 6 | View Details | [1277..1646] | |
21.39794 | Beta-ketoacyl-ACP synthase II |
| 7 | View Details | [1647..1713] | |
N/A | No confident structure predictions are available. |
| 8 | View Details | [1714..2051] | |
100.201249 | Catalytic domain of malonyl-CoA ACP transacylase FabD; Probable ACP-binding domain of malonyl-CoA ACP transacylase |
| Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
| Confidence of classification: | 0.55 |
Source: Reynolds et al. (2008)