YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: SNU66

General Information:
Name(s) found: SNU66 / YOR308C [SGD]
Description(s) found:
Found 28 descriptions.
SHOW ALL
  • Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; also required for pre-5S rRNA processing and may act in concert with Rnh70p; has homology to human SART-1 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 587 amino acids

    Gene Ontology:
    Cellular Component: U4/U6 x U5 tri-snRNP complex [IDALink to PubMed article][IPILink to PubMed article]
    Biological Process: nuclear mRNA splicing, via spliceosome [IMPLink to PubMed articleLink to PubMed article][IPILink to PubMed article]
    Molecular Function: RNA binding [RCA]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKTENLSIE ETNEIREKLG MKPIPVFQEK NTDHKESLSI EETNELRASL GLKLIPPQQN  60
   61 FNSSPPNVHN TSKIDELREK ITKFQKKANA PLRMAHLLEE TNVNDDSSWL ENMDAIPSSH 120
  121 ESKRSSTLPR KGATKEDENI DLHNVQVSYN IEALSPKKDT ILTLKESSIF DDTDSTEVLE 180
  181 NVKAAEENAD REKLRLRQMN KDRRQKKKIL NVSSLDIEEE EEGEKHSITT THLIIGAEQG 240
  241 VMKAPNTISA KPPTGKVKVN FDSANNMSDE DGGDFKPLKI KKRKIKDPRS TKARKSKITD 300
  301 KMEIVKLVDE DESLSWMEEE QPVTIINPRT SSNNELKGPE DLAREIEKAR DEEKRRTESI 360
  361 LKMREISNSI VVDEKVTFLN TLDTSLSERS ATENKVKVHG EGEKNIGDVT NGHTKEGSGN 420
  421 NTLTEAVNNE PNYEGDAENA PNFFSGLAST LGYLRKKSVF TTGDVDLKPG KDVNNSESLR 480
  481 RDVRNKEHTG TGTYTKDKLH GLEQFTSSDS SNANTHSKRQ DHYDPDIKLV YRDEKGNRLT 540
  541 TKEAYKKLSQ KFHGTKSNKK KRAKMKSRIE ARKNTPENGS LFEFDDN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) AAR2 BRR1 BRR2 CUS1 DHH1 DIB1 HSH155 LEA1 LIN1 LSM1 LSM2 LSM4 LSM6 LSM7 LSM8 PAT1 PRP11 PRP21 PRP3 PRP31 PRP38 PRP4 PRP40 PRP6 PRP8 PRP9 RSE1 SMB1 SMD1 SMD2 SMD3 SME1 SMX3 SNU114 SNU23 SNU66 SPP381
    View Details Krogan NJ, et al. (2006) AAR2 BRR1 BRR2 CSE1 LUC7 MUD1 NAM8 PRP2 PRP3 PRP31 PRP39 PRP40 PRP42 PRP6 PRP8 RRG7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNU114 SNU56 SNU66 SNU71 TAD2 YDL085C-A YHC1 YJU2 YNL092W
    View Details Gavin AC, et al. (2006) AAR2 BRR2 CUS1 GCN2 LEA1 PRP21 PRP3 PRP31 PRP4 PRP6 PRP8 PRP9 SMB1 SNU114 SNU23 SNU66 SPP381
    View Details Gavin AC, et al. (2002) AAR2 ASC1 BRR1 BRX1 BUD31 CBC2 CBF5 CDC33 CEF1 CIC1 CLF1 CSN12 CUS1 CWC2 CWC22 CWC23 DBP9 DCP2 DHH1 DIB1 DRS1 ECM2 ERB1 FUN12 GAR1 GCN2 HAS1 HRT1 HSH155 HSH49 HTA1 IMG1 KRE33 KRR1 KRS1 LEA1 LHP1 LIN1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 LUC7 MAK21 MDN1 MIS1 MRP7 MRPL28 MRPL3 MRPL35 MRPL38 MRPL4 MRPL8 MRPS5 MSL1 MUD1 NAM7 NAM8 NHP2 NIP1 NOC2 NOG1 NOG2 NOP1 NOP12 NOP2 NOP4 NOP56 NOP6 NOP7 NPL3 NUG1 PAT1 POL2 PRP11 PRP18 PRP19 PRP21 PRP24 PRP28 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP46 PRP6 PRP8 PRP9 PUF6 RLP7 RRP12 RSE1 RVB2 SLU7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNT309 SNU114 SNU23 SNU56 SNU66 SNU71 SPP381 SPP382 SQS1 SRB2 SRO9 STO1 SYF1 TIF4631 TIF4632 TOS4 URB1 UTP10 UTP20 UTP21 YEF3 YML6 YMR310C YTM1
    View Details Ho Y, et al. (2002) CRC1 MSI1 OLA1 PPZ1 RLF2 SNU66 TAF5
    View Details Qiu et al. (2008) AAR2 BRR1 BRR2 CBC2 CDC40 CEF1 CLF1 CUS1 CUS2 CWC15 CWC2 CWC22 CWC23 DHR2 DIB1 HSH155 IST3 ISY1 LEA1 LSM2 LSM3 LSM4 LSM5 LSM7 LUC7 MAK5 MSL1 MUD1 MUD2 NAM8 PRP11 PRP16 PRP18 PRP19 PRP2 PRP21 PRP22 PRP24 PRP28 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP5 PRP6 PRP8 PRP9 RSE1 SLU7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNU114 SNU23 SNU56 SNU66 SNU71 SPP2 SPP381 STO1 SYF1 SYF2 YHC1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CAB4 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen HUB1 SNU66 2 Unpublished Fields Lab Data
    View Screen HUB1 SNU66 2 Unpublished Fields Lab Data
    View Screen HUB1 SNU66 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SNU66 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..411] PSI-BLAST 2.09691 Heavy meromyosin subfragment
    2 View Details [412..587] MSA 2.020986 View MSA. No confident structure predictions are available.
    3 View Details [271..438] deduced N/A No confident structure predictions are available.
    4 View Details [439..587] FFAS03 0.96 Large T antigen, the N-terminal J domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.976140922616 bayes_pls_golite062009
  • protein binding
    		•  1.24691264244807 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.22205034569359 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.956364358495558 bayes_pls_golite062009
  • DNA binding
    		•  0.894959464232481 bayes_pls_golite062009
  • catalytic activity
    		•  0.137993331191769 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle