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Protein Overview: BRR2

Protein Complex Data

  PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
View Details Riffle et al. (2010) (Unpublished Data) AAR2 BRR1 BRR2 CDC40 CEF1 CLF1 CUS1 CWC2 CWC22 CWC23 DIB1 HSH155 KEM1 LEA1 LSM1 LSM2 LSM4 LSM6 LSM7 PAT1 PRP11 PRP19 PRP21 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP43 PRP46 PRP6 PRP8 PRP9 RSE1 SMB1 SMD1 SMD2 SMD3 SME1 SMX3 SNP1 SNT309 SNU114 SNU23 SNU66 SNU71 SPP382 STO1 SYF1
View Details Hazbun TR, et al. (2003) BRR2 CDC40 CEF1 CLF1 CWC2 CWC22 CWC23 ECM2 ISY1 LEA1 NTR2 PRP19 PRP43 PRP45 PRP46 PRP8 SMB1 SMD1 SMD3 SMX3 SNT309 SNU114 SPP382 SYF1 SYF2 YJU2
View Details (MIPS) Mewes HW, et al. (2004) AAR2 BRR1 BRR2 CBC2 CDC40 CWC15 CWC2 CWC22 CWC23 DHR2 LSM4 MAK5 MUD2 PRP16 PRP18 PRP2 PRP22 PRP24 PRP28 PRP31 PRP38 PRP39 PRP4 PRP40 PRP43 PRP5 PRP6 PRP8 SLU7 SMD1 SMD3 SME1 SNP1 SPP2 SPP381 STO1 YHC1
View Details Krogan NJ, et al. (2006) AAR2 BRR1 BRR2 CSE1 LUC7 MUD1 NAM8 PRP2 PRP3 PRP31 PRP39 PRP40 PRP42 PRP6 PRP8 RRG7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNU114 SNU56 SNU66 SNU71 TAD2 YDL085C-A YHC1 YJU2 YNL092W
View Details Gavin AC, et al. (2006) BRR2 CUS1 LEA1 PRP21 PRP3 PRP31 PRP4 PRP6 PRP8 PRP9 SMB1 SNU114 SNU23 SNU66 SPP381
View Details Ho Y, et al. (2002) ATP3 BRR2 PRP31 PRP6 RFC2 RFC3 RFC4 ROM2 VAC8
View Details Qiu et al. (2008) AAR2 BRR1 BRR2 BUD31 CBC2 CDC40 CEF1 CLF1 CUS1 CUS2 CWC15 CWC2 CWC21 CWC22 CWC23 CWC25 DBP6 DHR2 DIB1 ECM2 HSH155 IST3 ISY1 LEA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 LSM8 LUC7 MAK5 MSL1 MUD1 MUD2 NAM8 NTC20 PRP11 PRP16 PRP18 PRP19 PRP2 PRP21 PRP22 PRP24 PRP28 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP45 PRP46 PRP5 PRP6 PRP8 PRP9 RSE1 SLU7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNT309 SNU114 SNU23 SNU56 SNU66 SNU71 SPP2 SPP381 SPP382 STO1 SUB2 SYF1 SYF2 YHC1

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run CWC2 No Comments Hazbun TR, et al. (2003)
View Run SPP382 No Comments Hazbun TR, et al. (2003)
View Run SPP382 No Comments Hazbun TR, et al. (2003)
View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
View Run MLP2 #22 Asynchronous Prep2-IMAC Phosphopeptide enrichment B1-2 Keck JM, et al. (2011)
View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

  BAIT PREY HITS PUBLICATION
View Screen SGT1 BRR2 2 Unpublished Fields Lab Data

Microscopy / Localization Data

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  PROTEIN(S) PUBLICATION
View Data BRR2 Huh WK, et al. (2003)

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..131] MSA 1.019994 View MSA. No confident structure predictions are available.
2 View Details [132..211] deduced N/A Confident ab initio structure predictions are available.
3 View Details [212..464] MSA 4.418997 View MSA. No confident structure predictions are available.
4 View Details [465..698] PSI-BLAST 86.69897 Putative DEAD box RNA helicase
5 View Details [699..903] PSI-BLAST 86.69897 Putative DEAD box RNA helicase
6 View Details [904..1037] PSI-BLAST 5.69897 Nucleotide excision repair enzyme UvrB
7 View Details [1038..1318] deduced N/A No confident structure predictions are available.
8 View Details [1319..1784] MSA 72.257996 View MSA. No confident structure predictions are available.
9 View Details [1785..1920] deduced N/A No confident structure predictions are available.
10 View Details [1921..2087] PSI-BLAST 3.154902 Ribosomal protein L32e
11 View Details [2088..2163] deduced N/A Confident ab initio structure predictions are available.

Functions predicted (by domain):

# Gene Ontology predictions
1 No functions predicted.
2 No functions predicted.
3 No functions predicted.
4
Term Confidence Notes
  • 4.704140727858 bayes_pls_golite062009
  • structural constituent of ribosome
  • 3.070470376968 bayes_pls_golite062009
  • binding
  • 2.64537357529343 bayes_pls_golite062009
  • nucleic acid binding
  • 2.51683451033161 bayes_pls_golite062009
  • RNA binding
  • 2.29590582680214 bayes_pls_golite062009
  • structural molecule activity
  • 2.08211451183607 bayes_pls_golite062009
  • DNA binding
  • 1.94055378599526 bayes_pls_golite062009
  • transcription regulator activity
  • 1.83584389083042 bayes_pls_golite062009
  • RNA helicase activity
  • 1.42791449104435 bayes_pls_golite062009
  • RNA-dependent ATPase activity
  • 1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
  • 1.36724390116598 bayes_pls_golite062009
  • snRNA binding
  • 1.20045983086701 bayes_pls_golite062009
  • catalytic activity
  • 1.00104173493322 bayes_pls_golite062009
  • transcription factor activity
  • 0.959949409533517 bayes_pls_golite062009
  • mRNA binding
  • 0.76699944561918 bayes_pls_golite062009
  • helicase activity
  • 0.6191010101321 bayes_pls_golite062009
  • purine nucleotide binding
  • 0.569910969126728 bayes_pls_golite062009
  • purine ribonucleotide binding
  • 0.568840867400671 bayes_pls_golite062009
  • ribonucleotide binding
  • 0.568779924702229 bayes_pls_golite062009
  • nucleotide binding
  • 0.564275755355315 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
  • 0.312659433116074 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
  • 0.29664013896754 bayes_pls_golite062009
  • ATP-dependent helicase activity
  • 0.29664013896754 bayes_pls_golite062009
  • translation regulator activity
  • 0.29096092258568 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
  • 0.274994961137851 bayes_pls_golite062009
  • ATP binding
  • 0.1860481660648 bayes_pls_golite062009
  • protein binding
  • 0.170837278876362 bayes_pls_golite062009
  • adenyl ribonucleotide binding
  • 0.152859582615242 bayes_pls_golite062009
  • adenyl nucleotide binding
  • 0.138615225841109 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
  • 0.0530667986761242 bayes_pls_golite062009
  • pyrophosphatase activity
  • 0.0482442222493492 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
  • 0.028470639373934 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
  • 0.0265151533232588 bayes_pls_golite062009
    5
    Term Confidence Notes
  • structural molecule activity
  • 2.81579918518889 bayes_pls_golite062009
  • binding
  • 2.59063189683655 bayes_pls_golite062009
  • protein binding
  • 1.40069187357924 bayes_pls_golite062009
  • cation channel activity
  • 0.484734651147527 bayes_pls_golite062009
  • cytoskeletal protein binding
  • 0.448241458604601 bayes_pls_golite062009
  • ligand-gated ion channel activity
  • 0.445394181993741 bayes_pls_golite062009
  • ligand-gated channel activity
  • 0.445394181993741 bayes_pls_golite062009
  • gated channel activity
  • 0.437275980569276 bayes_pls_golite062009
  • ion channel activity
  • 0.351655405987795 bayes_pls_golite062009
  • actin binding
  • 0.328787215513486 bayes_pls_golite062009
  • substrate-specific channel activity
  • 0.21875054393881 bayes_pls_golite062009
  • channel activity
  • 0.196534845734361 bayes_pls_golite062009
  • passive transmembrane transporter activity
  • 0.196534845734361 bayes_pls_golite062009
    6
    Term Confidence Notes
  • 4.704140727858 bayes_pls_golite062009
  • structural constituent of ribosome
  • 3.070470376968 bayes_pls_golite062009
  • binding
  • 2.64537357529343 bayes_pls_golite062009
  • nucleic acid binding
  • 2.51683451033161 bayes_pls_golite062009
  • RNA binding
  • 2.29590582680214 bayes_pls_golite062009
  • structural molecule activity
  • 2.08211451183607 bayes_pls_golite062009
  • DNA binding
  • 1.94055378599526 bayes_pls_golite062009
  • transcription regulator activity
  • 1.83584389083042 bayes_pls_golite062009
  • RNA helicase activity
  • 1.42791449104435 bayes_pls_golite062009
  • RNA-dependent ATPase activity
  • 1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
  • 1.36724390116598 bayes_pls_golite062009
  • snRNA binding
  • 1.20045983086701 bayes_pls_golite062009
  • catalytic activity
  • 1.00104173493322 bayes_pls_golite062009
  • transcription factor activity
  • 0.959949409533517 bayes_pls_golite062009
  • mRNA binding
  • 0.76699944561918 bayes_pls_golite062009
  • helicase activity
  • 0.6191010101321 bayes_pls_golite062009
  • purine nucleotide binding
  • 0.569910969126728 bayes_pls_golite062009
  • purine ribonucleotide binding
  • 0.568840867400671 bayes_pls_golite062009
  • ribonucleotide binding
  • 0.568779924702229 bayes_pls_golite062009
  • nucleotide binding
  • 0.564275755355315 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
  • 0.312659433116074 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
  • 0.29664013896754 bayes_pls_golite062009
  • ATP-dependent helicase activity
  • 0.29664013896754 bayes_pls_golite062009
  • translation regulator activity
  • 0.29096092258568 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
  • 0.274994961137851 bayes_pls_golite062009
  • ATP binding
  • 0.1860481660648 bayes_pls_golite062009
  • protein binding
  • 0.170837278876362 bayes_pls_golite062009
  • adenyl ribonucleotide binding
  • 0.152859582615242 bayes_pls_golite062009
  • adenyl nucleotide binding
  • 0.138615225841109 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
  • 0.0530667986761242 bayes_pls_golite062009
  • pyrophosphatase activity
  • 0.0482442222493492 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
  • 0.028470639373934 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
  • 0.0265151533232588 bayes_pls_golite062009
    7 No functions predicted.
    8
    Term Confidence Notes
  • 6.55929165712784 bayes_pls_golite062009
  • RNA-dependent ATPase activity
  • 3.40791872038512 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
  • 3.40070584403887 bayes_pls_golite062009
  • RNA helicase activity
  • 3.25446655280881 bayes_pls_golite062009
  • structural molecule activity
  • 2.80935217964088 bayes_pls_golite062009
  • binding
  • 2.65544526722793 bayes_pls_golite062009
  • nucleic acid binding
  • 2.30172682093249 bayes_pls_golite062009
  • helicase activity
  • 1.87693598354249 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
  • 1.87127651162653 bayes_pls_golite062009
  • ATP-dependent helicase activity
  • 1.87127651162653 bayes_pls_golite062009
  • protein binding
  • 1.50286160643298 bayes_pls_golite062009
  • ligand-gated ion channel activity
  • 0.85500903576568 bayes_pls_golite062009
  • ligand-gated channel activity
  • 0.85500903576568 bayes_pls_golite062009
  • cation channel activity
  • 0.84907542359093 bayes_pls_golite062009
  • gated channel activity
  • 0.79614932073028 bayes_pls_golite062009
  • ion channel activity
  • 0.69968450497191 bayes_pls_golite062009
  • cytoskeletal protein binding
  • 0.60798225319459 bayes_pls_golite062009
  • substrate-specific channel activity
  • 0.554024107811049 bayes_pls_golite062009
  • actin binding
  • 0.54002000529721 bayes_pls_golite062009
  • channel activity
  • 0.52698001588063 bayes_pls_golite062009
  • passive transmembrane transporter activity
  • 0.52698001588063 bayes_pls_golite062009
  • voltage-gated cation channel activity
  • 0.410543003164924 bayes_pls_golite062009
  • voltage-gated channel activity
  • 0.272496099348536 bayes_pls_golite062009
  • voltage-gated ion channel activity
  • 0.236012840738827 bayes_pls_golite062009
    9 No functions predicted.
    10 No functions predicted.
    11 No functions predicted.




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle