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Bait Protein: CWC2
Organism: Saccharomyces cerevisiae
Publication: Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65
Comments: No comments.

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  Hit Protein Protein Desc Sequence Count Spectrum Count Sequence Coverage NSAF Mol. Wt.
[View Peptides]   SNT309 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 12 38 66.3% 0.104 20709
[View Peptides]   SMD1 Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and... 7 14 64.4% 0.0458 16275
[View Peptides]   SMD3 Core Sm protein Sm D3; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Sme1p, Smx3p, and... 5 10 62.4% 0.0473 11224
[View Peptides]   PRP19 Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiqu... 32 155 51.5% 0.147 56570
[View Peptides]   CWC2 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 21 40 50.7% 0.0564 38431
[View Peptides]   PRP45 Protein required for pre-mRNA splicing; associates with the spliceosome and interacts with splicing ... 17 38 46.4% 0.0479 42483
[View Peptides]   SNU114 GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; ... 35 83 42.7% 0.0394 114041
[View Peptides]   CEF1 Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb ... 23 55 38.6% 0.0446 67731
[View Peptides]   SYF2 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 7 13 37.2% 0.0289 24803
[View Peptides]   CDC40 Pre-mRNA splicing factor, important for catalytic step II of pre-mRNA splicing and plays a role in c... 13 25 37.1% 0.0263 52048
[View Peptides]   PRP46 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 18 40 36.6% 0.0424 50700
[View Peptides]   ECM2 Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association wit... 13 22 35.7% 0.0289 40925
[View Peptides]   CLF1 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 18 48 31.9% 0.0334 82445
[View Peptides]   SMD2 Core Sm protein Sm D2; part of heteroheptameric complex (with Smb1p, Smd1p, Smd3p, Sme1p, Smx3p, and... 3 10 31.8% 0.0435 12853
[View Peptides]   PRP8 Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing; mutation... 69 130 31.7% 0.0258 279502
[View Peptides]   SYF1 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 22 45 30.3% 0.025 100229
[View Peptides]   MSL1 U2B component of U2 snRNP, involved in splicing, binds the U2 snRNA stem-loop IV in vitro but requir... 2 3 27.0% 0.0129 12830
[View Peptides]   IST3 Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal as... 2 2 25.7% 0.00646 17098
[View Peptides]   LEA1 Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; p... 4 4 24.8% 0.00803 27193
[View Peptides]   SMB1 Core Sm protein Sm B; part of heteroheptameric complex (with Smd1p, Smd2p, Smd3p, Sme1p, Smx3p, and ... 4 13 23.0% 0.0317 22379
[View Peptides]   ATP7 Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily c... 2 2 21.8% 0.0055 19810
[View Peptides]   CWC15 Non-essential protein involved in pre-mRNA splicing, component of a complex containing Cef1p; has si... 3 5 19.4% 0.0137 19935
[View Peptides]   NTC20 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... 3 3 19.3% 0.0102 15970
[View Peptides]   MRPL13 Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation 3 3 18.5% 0.00522 31526
[View Peptides]   CWC23 Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to... 3 3 17.0% 0.00413 40951
[View Peptides]   PRP43 RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript... 9 12 15.5% 0.00748 87562
[View Peptides]   BRR2 RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in nativ... 23 35 14.8% 0.00774 246183
[View Peptides]   NTR2 Essential protein that forms a dimer with Ntr1p; also forms a trimer, with Ntr2p and the DExD/H-box ... 2 4 14.0% 0.00594 36647
[View Peptides]   SPP382 Essential protein that forms a dimer with Ntr2p; also forms a trimer, with Ntr2p and Prp43p, that is... 8 11 13.4% 0.00743 83049
[View Peptides]   BUD31 Component of the SF3b subcomplex of the U2 snRNP; diploid mutants display a random budding pattern i... 2 4 13.4% 0.0122 18447
[View Peptides]   CWC22 Essential protein, component of a complex containing Cef1p, has similarity to S. pombe Cwf22p; putat... 6 12 12.7% 0.00994 67294
[View Peptides]   CLC1 Clathrin light chain, subunit of the major coat protein involved in intracellular protein transport ... 2 6 12.4% 0.0123 26532
[View Peptides]   YJU2 Essential protein required for pre-mRNA splicing; associates transiently with the spliceosomal NTC (... 2 2 12.2% 0.00344 32312
[View Peptides]   SMX2 Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and ... 2 2 11.7% 0.0124 8482
[View Peptides]   HSH49 U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed... 2 2 11.3% 0.00449 24503
[View Peptides]   RSE1 Protein involved in pre-mRNA splicing; component of the pre-spliceosome; associates with U2 snRNA; i... 10 12 10.0% 0.00422 153784
[View Peptides]   BUD13 Subunit of the RES complex, which is required for nuclear pre-mRNA retention and splicing; involved ... 2 2 9.0% 0.00359 30472
[View Peptides]   HSH155 U2-snRNP associated splicing factor that forms extensive associations with the branch site-3' splice... 5 7 7.4% 0.00345 110028
[View Peptides]   CUS1 Protein required for assembly of U2 snRNP into the spliceosome, forms a complex with Hsh49p and Hsh1... 2 3 6.0% 0.00329 50253
[View Peptides]   SLY1 Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM (Sec1/Munc-18) fami... 2 2 3.9% 0.00144 74679
[View Peptides]   DRN1 Putative protein of unconfirmed function; green fluorescent protein (GFP)-fusion protein localizes t... 2 2 3.9% 0.00189 58206
[View Peptides]   MTC5 Protein of unknown function; mtc5 is synthetically sick with cdc13-1 2 2 2.4% 8.33E-4 130946
[View Peptides]   CDC25 Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); indirectly regulates ... 2 2 2.1% 6.02E-4 179091

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