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Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a RNA helix. Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments. Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate. Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA. Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA or RNA helix. Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA helix. Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate to drive the unwinding of a DNA or RNA helix.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: helicase activity
Acc: GO:0004386
Aspect: Molecular Function
Desc: Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA or RNA helix.
Proteins in PDR annotated with:
   This term: 661 [Search]
   Term or descendants: 1266 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004386 - helicase activity (interactive image map)
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