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View Structure Prediction Details

Protein: TAF5
Organism: Saccharomyces cerevisiae
Length: 798 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAF5.

Description E-value Query
Range
Subject
Range
gi|190408650 - gi|190408650|gb|EDV11915.1| transcription initiation factor TFIID subunit 5 [Saccharomyces cerevisia...
gi|207347572 - gi|207347572|gb|EDZ73698.1| YBR198Cp-like protein [Saccharomyces cerevisiae AWRI1631]
TAF5 - Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation...
TAF5_YEAST - Transcription initiation factor TFIID subunit 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...
0.0 [1..798] [1..798]
gi|17225204 - gi|17225204|gb|AAL37298.1|AF323582_1 beta transducin-like protein HET-E2C [Podospora anserina]
0.0 [351..797] [821..1240]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [293..797] [919..1431]
TAF5_SCHPO - Transcription initiation factor TFIID subunit 5 OS=Schizosaccharomyces pombe (strain 972 / ATCC 2484...
taf72 - transcription factor TFIID complex subunit 5 Taf72
0.0 [49..680] [2..576]

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Predicted Domain #1
Region A:
Residues: [1-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQKQSTNQN QNGTHQPQPV KNQRTNNAAG ANSGQQPQQQ SQGQSQQQGR SNGPFSASDL  60
   61 NRIVLEYLNK KGYHRTEAML RAESGRTLTP QNKQSPANTK TGKFPEQSSI PPNPGKTAKP 120
  121 ISNPTNLSSK RDAEGGIVSS GRLEGLNAPE NYIRAYSMLK NWVDS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [166-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLEIYKPELS YIMYPIFIYL FLNLVAKNPV YARRFFDRFS PDFKDFHGSE INRLFSVNSI  60
   61 DHIKENEVAS AFQSHKYRIT MSKTTLNLLL YFLNENESIG GSLIISVINQ HLDPNIVESV 120
  121 TAREKLADGI KVLSDSENGN GKQNLEMNSV PVKLGPFPKD EEFVKEIETE LKIKDDQEKQ 180
  181 LNQQTAGDNY SGANNRTLLQ EYKAMNNEKF KDNTGDDDKD KIKDKIAKDE EKKESEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [403-798]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVDGEKKDSN LSSPARDILP LPPKTALDLK LEIQKVKESR DAIKLDNLQL ALPSVCMYTF  60
   61 QNTNKDMSCL DFSDDCRIAA AGFQDSYIKI WSLDGSSLNN PNIALNNNDK DEDPTCKTLV 120
  121 GHSGTVYSTS FSPDNKYLLS GSEDKTVRLW SMDTHTALVS YKGHNHPVWD VSFSPLGHYF 180
  181 ATASHDQTAR LWSCDHIYPL RIFAGHLNDV DCVSFHPNGC YVFTGSSDKT CRMWDVSTGD 240
  241 SVRLFLGHTA PVISIAVCPD GRWLSTGSED GIINVWDIGT GKRLKQMRGH GKNAIYSLSY 300
  301 SKEGNVLISG GADHTVRVWD LKKATTEPSA EPDEPFIGYL GDVTASINQD IKEYGRRRTV 360
  361 IPTSDLVASF YTKKTPVFKV KFSRSNLALA GGAFRP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 291.512579
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [723-798]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKKATTEPSA EPDEPFIGYL GDVTASINQD IKEYGRRRTV IPTSDLVASF YTKKTPVFKV  60
   61 KFSRSNLALA GGAFRP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 97.045757
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle